Post-resuscitation Care Registry for Survival From Out-of-hospital Cardiac Arrest

The aim of this study is to construct multi-center post-cardiac arrest care registry that can be used for data warehousing and clinical research.

Study Overview

• Status: Completed
• Conditions: Out-Of-Hospital Cardiac Arrest

Detailed Description

This registry prospectively enrolls adults patients survived out-of-hospital cardiac arrest in 3 academic hospital emergency departments.

Registered data can be used for quality control and clinical research to reduce post-cardiac arrest syndrome-related mortality.

• Study Type: Observational
• Enrollment (Actual): 1057

Contacts and Locations

Study Locations

• Korea, Republic of
  • Seongnam-si, Korea, Republic of, 13620
    • Seoul National University Bundang Hospital
  • Seoul, Korea, Republic of, 03080
    • Seoul National University Hospital
  • Seoul, Korea, Republic of, 07061
    • Seoul National University Boramae Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients with sustained ROSC from OHCA

Description

Inclusion Criteria:

• Patients aged 20 years old or older who presents to the ED of the participating hospitals with any of the following criteria:

  1. Sustained ROSC from OHCA at pre-hospital level
  2. Sustained ROSC from OHCA at the ED of the participating hospitals after ACLS
  3. Patients sustained ROSC from OHCA and transferred from other hospital to the ED of the participating hospitals for post-cardiac arrest care

Exclusion Criteria:

• Age less than 20 years old
• Patients with advanced directives not to deliver aggressive organ supportive management

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Survival	One year survival	1-year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
28-day mortality	Mortality on the 28th day	28-day
28-day CPC	Brain function at 28th day	28-day
6-month CPC	Brain function at 6-month	6-month
1-year CPC	Brain function at 1-year	1-year
Organ support treatment (mechanical ventilation)	Mechanical ventilation	Hospital discharge (non-survivors) or 1-year (survivors)
Organ support treatment (renal replacement therapy)	Renal replacement therapy	Hospital discharge (non-survivors) or 1-year (survivors)
ICU length of stay	ICU length of stay	Hospital discharge (non-survivors) or 1-year (survivors)
Hospital length of stay	Hospital length of stay	Hospital discharge (non-survivors) or 1-year (survivors)

Collaborators and Investigators

• Sponsor: Seoul National University Hospital
• Collaborators: Seoul National University Bundang Hospital; SMG-SNU Boramae Medical Center
• Investigators: Study Director: Jonghwan Shin, MD, PhD, Seoul National University Boramae Hospital

Study record dates

Study Major Dates

• Study Start (Actual): December 3, 2013
• Primary Completion (Actual): December 31, 2019
• Study Completion (Actual): June 30, 2020

Study Registration Dates

• First Submitted: June 8, 2018
• First Submitted That Met QC Criteria: October 2, 2018
• First Posted (Actual): October 4, 2018

Study Record Updates

• Last Update Posted (Actual): February 18, 2022
• Last Update Submitted That Met QC Criteria: February 16, 2022
• Last Verified: February 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Diseases; Cardiovascular Diseases; Heart Arrest; Out-of-Hospital Cardiac Arrest
• Other Study ID Numbers: 16-2013-157

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No