Indirect Measurement of Respiratory Quotient in Coelioscopic Surgery

Validation of the Respiratory Quotient Measurement Measured Indirectly in Coelioscopic Surgery


Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Source Centre Hospitalier Universitaire, Amiens
Brief Summary

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured RQ from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room.

But, because of artificially increase of carbon dioxide due to insufflation, coelioscopic surgery was an exclusion criteria of our pilot study.

However, no study has examined the impact of coelioscopy on the indirect measurement of RQ

Overall Status Not yet recruiting
Start Date November 2018
Completion Date May 2019
Primary Completion Date May 2019
Study Type Observational
Primary Outcome
Measure Time Frame
Indirect respiratory quotient by measurement of VO2 and VCO2 during coelioscopic surgery
Secondary Outcome
Measure Time Frame
occurence of at least one post-operative complication through study completion, an average of 6 months
Enrollment 50

Intervention Type: Procedure

Intervention Name: coelioscopic surgery

Description: observational study based on the computation of respiratory quotient in patient cohort treated by routine coelioscopic surgery


Sampling Method: Non-Probability Sample


Inclusion Criteria:

- Age>18 years old

- Adults admitted to the operating room for coelioscopic surgery

Exclusion Criteria:

- Cardiac and thoracic surgery

- Preoperative oxygen therapy

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Overall Contact

Last Name: Stéphane Bar

Email: [email protected]

Verification Date

November 2018

Responsible Party

Type: Sponsor

Has Expanded Access No
Study Design Info

Observational Model: Cohort

Time Perspective: Prospective