IJV Catheterization and Intracranial Pressure Via ONSD

June 2, 2026 updated by: Oguz Gundogdu, Cumhuriyet University

Evaluation of the Effect of Internal Jugular Vein Catheterization on Intracranial Pressure Using Optic Nerve Sheath Diameter in Intubated Patients in the Intensive Care Unit

The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Before central venous catheter insertion, the baseline ONSD value will be determined by measuring the optic nerve sheath diameter in the supine and Trendelenburg positions (15 degrees head down).

Immediately after central venous catheter insertion, the measurement will be taken while the patient is still in the Trendelenburg position. The measurement will be repeated at 5, 15, and 30 minutes after the patient is placed in the supine position.

Transorbital optic nerve sheath diameter measurements will be performed using the linear probe of the ultrasound device routinely used in our clinic. The ultrasound linear probe will be gently placed on the eyelid over the closed eye, ensuring no pressure is applied to the patient's eye. The length of the line representing the optic nerve sheath diameter, which intersects the line drawn 3 mm downwards from the lower edge of the eyeball seen on the ultrasound, will be measured and recorded. The optic nerve sheath diameter will be measured transorbitally vertically once from each eye during the first measurement, and the average will be taken.

Study Type

Observational

Enrollment (Actual)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Sivas
      • Sivas, Sivas, Turkey (Türkiye), 58140
        • Sivas Cumhuriyet University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Intubated intensive care unit patients who receive internal jugular vein catheterization

Description

Inclusion Criteria:

  • The study will include adult patients over 18 years of age who are on mechanical ventilation support and monitored in the intensive care unit.

Exclusion Criteria:

  • patients with intracranial tumors
  • patients with acute traumatic brain injury
  • patients diagnosed with acute or chronic eye diseases
  • hypercarbic patients
  • Patients receiving inotropic support
  • patients using medications that affect intraocular pressure

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
IJV catheterization in ICU
Intubated patients in intensive care unit who receive internal jugular vein catheterization
Procedure: Internal jugular vein catheterization
Internal jugular vein catheterization

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Optic nerve sheath diameter
Time Frame: Prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization
Optic nerve sheath diameter will be measured via ultrasound prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization
Prior to IJV catheterization, and after 0, 5, 15, 30 minutes of catheterization

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cumhuriyet University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 1, 2026

Primary Completion (Actual)

May 28, 2026

Study Completion (Actual)

June 1, 2026

Study Registration Dates

First Submitted

March 7, 2026

First Submitted That Met QC Criteria

March 7, 2026

First Posted (Actual)

March 11, 2026

Study Record Updates

Last Update Posted (Actual)

June 3, 2026

Last Update Submitted That Met QC Criteria

June 2, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • 2025-05/28

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Intracranial Pressure Measurement

Clinical Trials on Internal jugular vein catheterization

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Taiwan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe