Endoscopic Findings of Gastritis in Children

February 26, 2020 updated by: HM Reyad, Assiut University

Retrospective Study on Endoscopic Findings of Gastritis in Children Attending GIT Endoscopic Unit of Assiut University Children Hospital (AUCH) (15 Years)

Gastritis defines any (histologically confirmed) inflammation of the gastric mucosa

Study Overview

Status

Unknown

Conditions

Detailed Description

Gastritis is a very common disease in children. The main presentation of children with gastritis is recurrent abdominal pain and dyspepsia or vomiting. Young children may have hematemesis or melena as presentation. Drug induced or food related gastritis presents usually with acute symptoms but Helicobacter pylori gastritis have mainly recurrent abdominal pain and dyspeptic symptoms. Other presentations include diarrhea, constipation, flatulence, bloating, fatigue, low energy level, weight loss, muscle loss, bad breath etc.

The main causes of gastritis are infections, inflammation and other disorders affect the gastric mucosa in pediatric patients. Helicobacter pylori infection is the most common cause of gastritis in children which is also responsible for the majority of duodenal ulcers.

Acute erosive gastritis is most commonly the result of metabolic stress or drug or corrosive injury.

Other major causes of gastritis include celiac disease, allergic disorders, and Crohn's disease .Medication as NSAIDs, uremia, ischemia, shock, radiation, sepsis, trauma, severe burns and surgery.

Endoscopic pictures in acute gastritis may be in the form of:

  • Multiple round-shaped severe erosions with a diameter of several millimeters.
  • Mucosal edema, hyperemia.
  • Peptic ulcer While in chronic gastritis is variable. Affects the antrum in the beginning and advances to the proximal in time .

Study Type

Observational

Enrollment (Anticipated)

500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

No older than 18 years (Child, Adult)

Accepts Healthy Volunteers

N/A

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy

Description

Inclusion Criteria:

  • All children diagnosed as gastritis by upper endoscopy and bio gastric biopsy

Exclusion Criteria:

  • • All children underwent upper endoscopy during the study period not diagnosed as gastritis

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Retrospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
causes of gastritis in children as shown by upper endoscopy
Time Frame: average 1 year
  • infections
  • inflammation
  • Helicobacter pylori
  • Acute erosive gastritis
average 1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Anticipated)

September 30, 2020

Primary Completion (Anticipated)

October 30, 2020

Study Completion (Anticipated)

April 30, 2021

Study Registration Dates

First Submitted

September 23, 2019

First Submitted That Met QC Criteria

February 26, 2020

First Posted (Actual)

February 28, 2020

Study Record Updates

Last Update Posted (Actual)

February 28, 2020

Last Update Submitted That Met QC Criteria

February 26, 2020

Last Verified

February 1, 2020

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • EFOGIC

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Gastritis

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in New Zealand

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe