Psychoactive Drug Uses Among Medical and Pharmacy Students (PSYCHO'ACT)

Drug addiction to psychoactive substances, widely consumed in France, represents a major public health issue. The three main motivations identified for the consumption of psychostimulants would be self-medication, the party aspect and the improvement of school performance. Students of medicine and pharmacy are a population exposed to academic and professional stress, vulnerable to health problems and psycho-social disorders (anxiety, depression), with direct access to many drugs at their workplace. Almost a third of these students declared to consume these products to improve their cognitive performance, while a recent study showed that they take them instead to manage their stress and sleep. However, no study has characterized all the different uses of psychoactive drugs (PAD) in this population, nor the motivations for consumption, while an analysis of motives would help to develop better screening and prevention strategies. The main objective of the research is to characterize the motivations for PAD consumption among students of medicine and pharmacy in France. The most represented motives will be analyzed on the questionnaire of motivations for consumption (threshold frequency ≥20%). The secondary objectives are to identify the risk factors linked to the individual, to the environment and to drugs in students with PAD use disorders regardless of their motivation and in those using to improve their performance.

Study Overview

• Status: Completed
• Conditions: Psychoactive Substance Use Disorder

• Study Type: Observational
• Enrollment (Actual): 1930

Contacts and Locations

Study Locations

• France
  • Grenoble, France, 38043
    • Grenoble_Alpes UniversityHospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

medical and pharmacy students, from the 2nd to the 6th year, in France

Description

Inclusion Criteria:

• Being of legal age
• Studying medicine or pharmacy in France from the 2nd to the 6th year
• Have read the newsletter and validated its no objection
• Have answered all the questions
• Validate the return of the questionnaire

Exclusion Criteria:

• partial filling of the online questionnaire

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The main objective of the research is to characterize the motivations for psychoactive drugs consumption among medical and pharmacy students in France.	frequency of the most represented items concerning the main palatability drug on the Consumption Motivation Screening Questionnaire (frequency threshold considered ≥ 20%). (the minimum value of the questionnaire: 0 motivation of consumption; the maximum value: 110 motivations of consumption, higher scores mean a more severe addiction)	two months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
In students with a psychoactive drug use disorder whatever their motivations, identify the risk factors related to the individual (anxiety)	assessment the intensity of anxiety on the Hospital Anxiety and Depression scale (the minimum value of the scale : 0 for Anxiety, 0 for Depression; the maximum value: 21 for Anxiety, 21 for depression; higher scores mean a worse outcome)	two months
In students with a psychoactive drug use disorder whatever their motivations, identify the risk factors related to the individual (depression)	assessment the intensity of depression on the Hospital Anxiety and Depression scale (the minimum value of the scale : 0 for Anxiety, 0 for Depression; the maximum value: 21 for Anxiety, 21 for depression; higher scores mean a worse outcome)	two months
In students with a psychoactive drug use disorder whatever their motivations, identify the risk factors related to the environment	family psychiatric history Psycho'act questionnaire	two months
In students with a psychoactive drug use disorder whatever their motivations, identify the risk factors related to drugs.	assessment of the intensity of the psychoactive drug use disorder with the Addictive Intensity Evaluation Questionnaire (the minimum value of the questionnaire : 14; the maximum value: 98; higher scores mean a worse outcome)	two months
In students with psychoactive drug use disorder for doping purposes, identify risk factors related to the individual (anxiety)	assessment the intensity of anxiety on the Hospital Anxiety and Depression scale (the minimum value of the scale : 0 for Anxiety, 0 for Depression; the maximum value: 21 for Anxiety, 21 for depression; higher scores mean a worse outcome)	two months
In students with psychoactive drug use disorder for doping purposes, identify risk factors related to the individual (depression)	assessment the intensity of depression on the Hospital Anxiety and Depression scale (the minimum value of the scale : 0 for Anxiety, 0 for Depression; the maximum value: 21 for Anxiety, 21 for depression; higher scores mean a worse outcome)	two months
In students with psychoactive drug use disorder for doping purposes, identify risk factors related to the environment	family psychiatric history Psycho'act questionnaire	two months
In students with psychoactive drug use disorder for doping purposes, identify risk factors related to drugs.	assessment of the intensity of the psychoactive drug use disorder with the Addictive Intensity Evaluation Questionnaire (the minimum value of the questionnaire : 14; the maximum value: 98; higher scores mean a worse outcome)	two months

Collaborators and Investigators

• Sponsor: University Hospital, Grenoble

Study record dates

Study Major Dates

• Study Start (Actual): January 24, 2022
• Primary Completion (Actual): March 21, 2022
• Study Completion (Actual): March 21, 2022

Study Registration Dates

• First Submitted: September 27, 2021
• First Submitted That Met QC Criteria: October 29, 2021
• First Posted (Actual): November 10, 2021

Study Record Updates

• Last Update Posted (Actual): May 9, 2022
• Last Update Submitted That Met QC Criteria: May 6, 2022
• Last Verified: May 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Chemically-Induced Disorders; Substance-Related Disorders
• Other Study ID Numbers: 38RC20.161; 2020-A01352-37 (Other Identifier: ID RCB)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No