The Effect of Brief Bodyweight Exercise on Acute Glycemic Control in Healthy Inactive Adults

This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control refers to the process of how the body regulates blood sugar. The process can be measured in different ways. This study will use a small device called a continuous glucose monitor to measure changes in glucose levels over a 24-hour period. Participants will complete two trials and the investigators will compare glycemic control after the exercise session and a control period that does not involve exercise. Food intake will be controlled such that each participant will consume the same diet in both conditions. This study will help determine whether a single session of bodyweight exercise affects glycemic control.

Study Overview

• Status: Completed
• Conditions: Exercise
• Intervention / Treatment: Other: Exercise

Detailed Description

This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control will be assessed using continuous glucose monitoring for 24 hours following exercise or a control condition that does not involve exercise. The exercise and control periods will be directly supervised by a study investigator. Participants will complete two trials in a randomized, crossover manner separated by 7 days. Food intake will be controlled such that each participant will consume the same diet over the 24-hour period of measurement in both conditions. Standardized meals will be provided to participants prior and following the exercise and control conditions. This study will determine whether a single session of bodyweight exercise affects glycemic control as primarily assessed by mean 24-hour glucose.

• Study Type: Interventional
• Enrollment (Actual): 35
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Canada
  • Ontario
    • Hamilton, Ontario, Canada, L8S4K1
      • McMaster University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 35 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Inactive, defined as not meeting the physical activity targets in the Canadian 24-Hour Movement Guidelines for Adults.
• Deemed able to safely participate in physical activity and exercise, as determined by the Canadian Society for Exercise Physiology (CSEP) Get Active Questionnaire prescreening tool.

Exclusion Criteria:

- Experiencing a condition that might preclude safe participation in physical activity and exercise, as determined by answering "Yes" to any question on Page 1 of the CSEP Get Active Questionnaire.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Bodyweight Exercise; A standardized 11-minute bodyweight exercise session that involves a 1-minute warm-up followed by 5, 1-minute bouts of exercise at a self-selected "challenging" pace, interspersed with 1-minute periods of low-intensity exercise for recovery.	Other: Exercise; A single session of bodyweight exercise
No Intervention: Non-Exercise Control; An 11-minute period of quiet sitting.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
24-hour mean glucose	Mean glucose following the bodyweight exercise or control condition	24-hour measurement period

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Glycemic variability	Variability in glucose measured following exercise or control	24-hour measurement period
Peak glucose	Peak glucose measured after each meal following exercise or control	2-hour measurement period after each meal
2-hour postprandial mean glucose	Mean glucose measured after each meal following exercise or control	2-hour measurement period after each meal

Collaborators and Investigators

• Sponsor: McMaster University
• Collaborators: York University

Study record dates

Study Major Dates

• Study Start (Actual): December 6, 2021
• Primary Completion (Actual): June 30, 2022
• Study Completion (Actual): June 30, 2022

Study Registration Dates

• First Submitted: November 22, 2021
• First Submitted That Met QC Criteria: November 22, 2021
• First Posted (Actual): December 3, 2021

Study Record Updates

• Last Update Posted (Actual): July 12, 2022
• Last Update Submitted That Met QC Criteria: July 8, 2022
• Last Verified: July 1, 2022

More Information

Terms related to this study

• Keywords: Glycemic Control
• Additional Relevant MeSH Terms: Body Weight
• Other Study ID Numbers: 13864

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No