Anatomical Variation in Rouvière's Sulcus

Anatomical Variation in Rouvière's Sulcus: a Cross-sectional Study

Rouvière's sulcus is a 2-5 cm fissure lying on the lower face of the liver, between the right lobe and caudate process. Due to its extrabiliary location, Rouvière's Sulcus could be used as an anatomical landmark for safe laparoscopic cholecystectomy. In literature there's an high variability about Rouvière Sulcus prevalence and its anatomical variants.

Study Overview

• Status: Not yet recruiting
• Conditions: Rouvière's Sulcus
• Intervention / Treatment: Procedure: Videolaparoscopic cholecystectomy

Detailed Description

The goal of this observational study is to evaluate the presence of Rouvière Sulcus in patients underwent laparoscopic cholecystectomy. The main questions it aims to answer are the prevalence and the anatomical variations of Rouvière's Sulcus and the variants of Rouvière's Sulcus which are catheghorized according to Singh and Prasad criteria.

The following were considered secondary outcome: operative time expressed in minutes, biliary tract injuries according to Stewart's classification and Vascular injuries.

• Study Type: Observational
• Enrollment (Estimated): 1000

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Laparoscopic cholecystectomy

Description

Inclusion Criteria:

• Patients undergoing videolaparoscopic cholecystectomy

Exclusion Criteria:

• If the lower face of the right hepatic lobe and the main elements of the biliary tract cannot be clearly analyzed patients will be excluded.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Videolaparoscopic cholecystectomy; Patients undergoing Videolaparoscopic cholecystectomy	Procedure: Videolaparoscopic cholecystectomy; Evaluation of Rouvière's Sulcus Anatomical Variation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of Rouvière's Sulcus		2 years
Anatomical variations in Rouvière's Sulcus	The variants of the Rouvière's Sulcus are catheghorized by the classification of Singh e Prasad.	2 years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Operative time	Time expressed in minutes	2 years
Biliary tract injuries	Biliary tract injuries according to Stewart's classification.	2 years
Vascular injuries	Vascular injuries.	2 years

Collaborators and Investigators

• Sponsor: University Of Perugia
• Collaborators: Giovanni Domenico Tebala; Luca Properzi; Nereo Vettoretto; Matteo Matteucci; Antonio Pesce; Carlo Boselli; Antonia Rizzuto; Augusto Lauro

Publications and helpful links

General Publications

• Singh M, Prasad N. The anatomy of Rouviere's sulcus as seen during laparoscopic cholecystectomy: A proposed classification. J Minim Access Surg. 2017 Apr-Jun;13(2):89-95. doi: 10.4103/0972-9941.201731.
• Stewart L. Iatrogenic biliary injuries: identification, classification, and management. Surg Clin North Am. 2014 Apr;94(2):297-310. doi: 10.1016/j.suc.2014.01.008.
• Pesce A, Fabbri N, Feo CV. Vascular injury during laparoscopic cholecystectomy: An often-overlooked complication. World J Gastrointest Surg. 2023 Mar 27;15(3):338-345. doi: 10.4240/wjgs.v15.i3.338.

Study record dates

Study Major Dates

• Study Start (Estimated): September 1, 2024
• Primary Completion (Estimated): August 31, 2025
• Study Completion (Estimated): August 31, 2026

Study Registration Dates

• First Submitted: June 10, 2023
• First Submitted That Met QC Criteria: June 10, 2023
• First Posted (Actual): June 22, 2023

Study Record Updates

• Last Update Posted (Actual): July 5, 2024
• Last Update Submitted That Met QC Criteria: July 2, 2024
• Last Verified: July 1, 2024

More Information

Terms related to this study

• Keywords: Prevalence Rouvière's Sulcus; Anatomical variations Rouvière's Sulcus
• Other Study ID Numbers: AVRS1

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No