Clinicopathological Profile of Head and Neck Cancers in Army Hospital of Nepal

Clinicopathological Profile of Head and Neck Cancers in Army Hospital of Nepal - A Retrospective Study

This is a observational study conducted at the department of Ear ,Nose and Throat -Head and Neck Surgery (ENT-HNS) of Shree Birendra Hospital ,a tertiary health care centre of Nepal. Head and Neck cancers are the sixth most common cancer in the world. Data was collected from the medical records of Head and Neck Cancer patients who underwent treatment between May 2022 to April 2023.The main aim of the study was to know about the common cancers of head and neck region and their distribution according to the site. Also to know the stage of the presentation with treatment modalities in the tertiary health care centre of Nepal.

Study Overview

• Status: Completed
• Conditions: Head and Neck Cancer

Detailed Description

This is a retrospective study to know the prevalence of Head and Neck Cancer at the department of ENT- Head and Neck Surgery of Shree Birendra Hospital ,a tertiary health care centre of Nepal .Head and neck cancers are malignant neoplasms that develops in oral cavity, nasal cavities, paranasal sinuses,nasopharynx, oropharynx, hypopharynx, ear, scalp, salivary gland and neck,Data was collected from the medical records of Head and Neck Cancer patients who underwent treatment between May 2022 to April 2023. Data considered of demographic details of age, sex, diagnosis, subsite specific Head and Neck Cancers, treatment modality and histopathology. The data was analyzed using Stastical Package for Social Sciences (SPSS) version 22. Pearson's chi-square test was applied and p value <0.05 was considered statistically significant.

• Study Type: Observational
• Enrollment (Actual): 76

Contacts and Locations

Study Locations

• Nepal
  • Kathmandu, Nepal, 977
    • Shree Birendra Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Study population was selected from the tertiary care centre of Nepal.

Description

Inclusion Criteria:

• All histologically proven cases of head and neck region.

Exclusion Criteria:

• Patient's record with incomplete data.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Age - wise Distribution of Head and Neck Cancers (HNCs)	Age - wise Distribution of Head and Neck Cancer	1 year
: Distribution of HNCs according to subsite	Distribution of Head and Neck Cancers according to the subsite	1 year
Histopathology of HNCs	Histopathology of Head and Neck Cancer	1 year
Tumor, Nodes, Metastasis (TNM) staging of HNC	Staging at presentation of Head and Neck Cancer	1 year
Treatment provided to HNC patients	Treatment Modalities of Head and Neck Cancer	1 year

Collaborators and Investigators

• Sponsor: Tribhuvan University, Nepal
• Investigators: Principal Investigator: Reeba Karki, MS, Shree Birendra Hospital

Publications and helpful links

General Publications

• Chin D, Boyle GM, Porceddu S, Theile DR, Parsons PG, Coman WB. Head and neck cancer: past, present and future. Expert Rev Anticancer Ther. 2006 Jul;6(7):1111-8. doi: 10.1586/14737140.6.7.1111.

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2022
• Primary Completion (Actual): April 30, 2023
• Study Completion (Actual): April 30, 2023

Study Registration Dates

• First Submitted: November 21, 2023
• First Submitted That Met QC Criteria: November 21, 2023
• First Posted (Actual): November 30, 2023

Study Record Updates

• Last Update Posted (Actual): November 30, 2023
• Last Update Submitted That Met QC Criteria: November 21, 2023
• Last Verified: November 1, 2023

More Information

Terms related to this study

• Keywords: Head and Neck Cancer; Radiotherapy; Chemotherapy
• Additional Relevant MeSH Terms: Neoplasms; Neoplasms by Site; Head and Neck Neoplasms
• Other Study ID Numbers: 245

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: There is no plan to share the individual participant data to protect the privacy of the participants.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No