Analysis of Ocular Complications of AIDS Patients in Ophthalmic Consultation

February 8, 2024 updated by: Zhongnan Hospital
Through a cross-sectional descriptive analysis of ophthalmic consultation of AIDS patients in the past 3 years, the basic characteristics of patients were described according to whether there was fundus change, and the clinical characteristics and risk factors of CMVR patients with or without RD were compared.

Study Overview

Status

Active, not recruiting

Conditions

Detailed Description

Patients were divided into normal group, opportunistic infection group, microangiopathopathy group and uveitis group according to the presence of fundus lesions and the types of fundus lesions. The basic information and characteristics of patients in different groups were described. The factors that may be related to ocular fundus disease of AIDS patients were found by statistical analysis.

Study Type

Observational

Enrollment (Estimated)

500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Hubei
      • Wuhan, Hubei, China, 430000
        • Zhongnan Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

HIV/AIDS patients hospitalized in the infection department at ZhongNan Hospital with ophthalmic consultation during November 19th, 2019 to June 9th ,2023 were included.

Description

Inclusion Criteria:

  • AIDS inpatient undergoing ophthalmic consultation

Exclusion Criteria:

  • Non-hiv infected patients

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
without ocular complication
The normal group was compared with the pathological group
fundus opportunistic infections
AIDS patients are prone to opportunistic fundus infection, which show a characteristic changes in fundus photography. It was designed to describe the characteristics of this group of patients.
Microvascular disease
Microvascular disease is an early characteristic of fundus changes in AIDS patients, with characteristic changes in fundus photography.
uveitis
The uveitis patients in this study were mainly caused by treponema pallidum infection.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
fundus photo changes
Time Frame: The classification was based on a review of the fundus examination of the patient at the time of the 1 day visit
Early changes(microangiopathy) appear as small, white, scattered retinal infiltrations. And the typical change of CMVR is full-layer, cheesy retinal necrosis with extensive retinal bleeding in the distal region.
The classification was based on a review of the fundus examination of the patient at the time of the 1 day visit

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zhongnan Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 1, 2023

Primary Completion (Estimated)

February 28, 2024

Study Completion (Estimated)

March 28, 2024

Study Registration Dates

First Submitted

February 1, 2024

First Submitted That Met QC Criteria

February 8, 2024

First Posted (Actual)

February 9, 2024

Study Record Updates

Last Update Posted (Actual)

February 9, 2024

Last Update Submitted That Met QC Criteria

February 8, 2024

Last Verified

November 1, 2023

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 20231119

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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