Combine Effects of Brunnstorm Movement Therapy and LLLT in Chronic Stroke Patient

Combine Effects of Brunnstorm Movement Therapy and LLLT on Upper Limb Functioning and Hand Dexterity in Chronic Stroke Patient

The primary objective of this study is to determine the combined effects of Brunnstorm movement therapy and low level laser therapy on upper limb function in chronic stroke patient.

Study Overview

• Status: Completed
• Conditions: Chronic Stroke
• Intervention / Treatment: Other: Brunnstorm movement therapy; Other: Combined Brunnstorm Movement therapy and low level laser therapy

• Study Type: Interventional
• Enrollment (Actual): 48
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Lahore, Punjab, Pakistan, 54000
      • Govt. Mian Munshi DHQ Teaching hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Age range between 40 & 60 years (16)
• Both males and females.
• Combined Effects of Brunnstorm movement therapy and LLLT on Upper limb function Hand dexterity in stroke
• Patient with maximum Grade 1 and 1+ spasticity according to Modified
• Ashworth scale and minimum muscle strength of 1 in the biceps brachii muscle.
• Onset of injury : (1 to 2 years)

Exclusion Criteria:

• Any comorbidity such as malignancy, inflammatory rheumatologic disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus erythematosus, etc.
• Have a pacemaker or a history of serious cardiac events or of cardiorespiratory dysfunction.
• Visual impairment
• Any other musculoskeletal disorders of extremity
• Severe cognitive impairment or aphasia leading to difficulty in communication, Participants unwilling to comply with the protocol.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Brunnstorm Movement therapy; this group received Brunnstorm Movement therapy for 3 to 5 sessions per week, each lasting approximately 30 to 60 minutes for 6 weeks	Other: Brunnstorm movement therapy; this group received Brunnstorm Movement therapy for 3 to 5 sessions per week, each lasting approximately 30 to 60 minutes for 6 weeks
Experimental: Combined Brunnstorm Movement therapy and low level laser therapy; this group received Combined Brunnstorm Movement therapy and low level laser therapy for 3 to 5 sessions per week, each lasting approximately 30 to 60 minutes for 6 weeks	Other: Combined Brunnstorm Movement therapy and low level laser therapy; this group received Combined Brunnstorm Movement therapy and low level laser therapy for 3 to 5 sessions per week, each lasting approximately 30 to 60 minutes for 6 weeks

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Fugle meyer Assessment test		6th week
Box and block test		6th week
Nine peg hole test		6th week
to check Muscle tone	Modified Ashworth Scale	6th week
to measure grip Strength	Hand handled dynamometer	6th week

Collaborators and Investigators

• Sponsor: Riphah International University
• Investigators: Principal Investigator: Binash Afzal, PHD*, Riphah International University Lahore Campus

Publications and helpful links

General Publications

• da Silva BP, Souza GADS, Filho AADN, Pinto AP, Guimaraes CL, Pereira APC, Neves MFD, Martins PSLL, Lima FPS, Lopes-Martins RAB, Lima MO. Analysis of the effects of low-level laser therapy on muscle fatigue of the biceps brachii muscle of healthy individuals and spastic individuals: Study protocol for a single-center, randomized, double-blind, and controlled clinical trial. Medicine (Baltimore). 2019 Sep;98(39):e17166. doi: 10.1097/MD.0000000000017166.
• das Neves MF, Aleixo DC, Mendes IS, Lima FPS, Nicolau RA, Arisawa EAL, Lopes-Martins RAB, Lima MO. Long-term analyses of spastic muscle behavior in chronic poststroke patients after near-infrared low-level laser therapy (808 nm): a double-blinded placebo-controlled clinical trial. Lasers Med Sci. 2020 Sep;35(7):1459-1467. doi: 10.1007/s10103-019-02920-3. Epub 2019 Dec 10.
• Azuma RHE, Merlo JK, Jacinto JL, Borim JM, da Silva RA, Pacagnelli FL, Nunes JP, Ribeiro AS, Aguiar AF. Photobiomodulation Therapy at 808 nm Does Not Improve Biceps Brachii Performance to Exhaustion and Delayed-Onset Muscle Soreness in Young Adult Women: A Randomized, Controlled, Crossover Trial. Front Physiol. 2021 Jun 10;12:664582. doi: 10.3389/fphys.2021.664582. eCollection 2021.
• Stamborowski SF, de Oliveira Spinelli BM, Lima FPS, Costa DR, de Silveira Souza GA, Lima MO, Lopes Martins RAB. The influence of photobiomodulation on the temperature of the brachial biceps during muscle fatigue protocol. Lasers Med Sci. 2021 Oct;36(8):1741-1749. doi: 10.1007/s10103-021-03360-8. Epub 2021 Jul 13.
• Vassao PG, Baldini GS, Vieira KVSG, Balao AB, Pinfildi CE, Campos RMDS, Tucci HT, Renno ACM. Acute Photobiomodulation Effects Through a Cluster Device on Skeletal Muscle Fatigue of Biceps Brachii in Young and Healthy Males: A Randomized Double-Blind Session. Photobiomodul Photomed Laser Surg. 2020 Dec;38(12):773-779. doi: 10.1089/photob.2019.4786.
• Harada T, Miyagi M, Izukura H, Endou G, Ushigome N, Tsuruoka H, Mizutani A, Ohshiro T, Ebihara S. The effect of low level laser therapy for pain in major muscles controlling two joints. Laser Ther. 2019 Jun 30;28(2):111-115. doi: 10.5978/islsm.19-OR-07.

Study record dates

Study Major Dates

• Study Start (Actual): August 1, 2023
• Primary Completion (Actual): September 30, 2023
• Study Completion (Actual): October 10, 2023

Study Registration Dates

• First Submitted: January 28, 2024
• First Submitted That Met QC Criteria: March 4, 2024
• First Posted (Estimated): March 5, 2024

Study Record Updates

• Last Update Posted (Estimated): March 5, 2024
• Last Update Submitted That Met QC Criteria: March 4, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Keywords: Stroke; Low-level laser therapy; Brunnstorm movement therapy; Hand dexterity
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Stroke
• Other Study ID Numbers: REC/RCR&AHS/23/0240

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No