Comparison Of Measured To Predicted Resting Metabolism

July 28, 2025 updated by: Angela Hillman, Ohio University
The purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Resting metabolic rate (RMR) describes the number of calories a person utilizes while at rest. The gold standard measurement is via inspired and expired air using a metabolic cart. However, researchers have established estimation equations and the use of body composition analysis to predict RMR when a metabolic cart is unavailable. The accuracy of the predicted equations and whole-body bioelectrical impedance (BIA) machines that produce this data is unknown. Therefore, the purpose of this study is to compare RMR values from the BIA, predicted equations, and indirect calorimetry.

Aim 1: to compare measured RMR from indirect calorimetry to values provided by the InBody 770 BIA machine and to established gender and age-appropriate prediction equations.

Aim 2: to compare RMR measured from indirect calorimetry using a metabolic cart (Gold Standard) to the Medgem handheld indirect calorimeter (FDA approved device).

Study Type

Observational

Enrollment (Actual)

90

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Ohio
      • Athens, Ohio, United States, 45701
        • Ohio University Exercise Physiology Lab

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Men & women, aged 18-60 in cohorts by age: 18-24, 24-29, 30-39, 40-49, and 50-60 years of age

Description

Inclusion Criteria:

  • Men & women, aged 18-60

Exclusion Criteria:

  • Have any known or suspected metabolic diseases such as diabetes, thyroid disorder, or high cholesterol
  • Have any known or suspected cardiovascular or pulmonary diseases such as hypertension
  • Are currently on beta blockers, taking antihypertensives, or antidepressants
  • Current smoker or quit less than a year ago
  • Unwilling to provide finger stick and urine sample

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
18-24 years old
Diagnostic test: Metabolic cart
RMR measurement via metabolic cart
Diagnostic test: MedGem
RMR measurement via MedGem
Diagnostic test: BIA
RMR estimation from BIA analysis
24-29 years old
Diagnostic test: Metabolic cart
RMR measurement via metabolic cart
Diagnostic test: MedGem
RMR measurement via MedGem
Diagnostic test: BIA
RMR estimation from BIA analysis
30-39 years old
Diagnostic test: Metabolic cart
RMR measurement via metabolic cart
Diagnostic test: MedGem
RMR measurement via MedGem
Diagnostic test: BIA
RMR estimation from BIA analysis
40-49 years old
Diagnostic test: Metabolic cart
RMR measurement via metabolic cart
Diagnostic test: MedGem
RMR measurement via MedGem
Diagnostic test: BIA
RMR estimation from BIA analysis
50-60 years old
Diagnostic test: Metabolic cart
RMR measurement via metabolic cart
Diagnostic test: MedGem
RMR measurement via MedGem
Diagnostic test: BIA
RMR estimation from BIA analysis

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Resting metabolic rate
Time Frame: day 1
day 1

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Ohio University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 14, 2023

Primary Completion (Actual)

December 31, 2024

Study Completion (Actual)

December 31, 2024

Study Registration Dates

First Submitted

March 29, 2024

First Submitted That Met QC Criteria

April 4, 2024

First Posted (Actual)

April 5, 2024

Study Record Updates

Last Update Posted (Actual)

July 30, 2025

Last Update Submitted That Met QC Criteria

July 28, 2025

Last Verified

July 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 22-X-187

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

Yes

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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