Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery

September 17, 2025 updated by: Faruk Komez, Istanbul Medeniyet University
This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

105

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Patients scheduled for laparoscopic cholecystectomy surgery
  • Patients aged between 18 to 80 years
  • Having an anesthesiology risk assessment of ASA I, II, or III

Exclusion Criteria:

  • Patients who do not give written and oral consent
  • Patients with coagulopathy
  • History of allergic reaction or intoxication by local anesthetics
  • Severe organ failure
  • Mental retardation or illiteracy
  • Presence of infection on the injection site
  • Pregnancy
  • Patients whom the procedure is extended to open cholecystectomy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Group 1: subcostal transversus abdominis plane block
This group will receive 30 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery.
Procedure: subcostal transversus abdominis plane block
Under ultrasound guidance, 30 ml of bupivacaine is injected along the fascia of transversus abdominis muscle.
Active Comparator: Group 2: external oblique intercostal plane block
This group will receive 30 ml 0.25% of bupivacaine for the external oblique intercostal plane block prior to surgery.
Procedure: External Oblique Intercostal Plane Block
Under ultrasound guidance, 30 ml of bupivacaine is injected between the fascias of external oblique and intercostal muscles.
Active Comparator: Group 3: subcostal transversus abdominis and external oblique intercostal plane block combination
This group will receive 15 ml 0.25% of bupivacaine for the external oblique intercostal plane block, in combination with 15 ml 0.25% of bupivacaine for the subcostal transversus abdominis plane block prior to surgery.
Procedure: external oblique intercostal plane block and subcostal transversus abdominis plane block combination
The combination of the two blocks will be applied in 15 ml of volume for each.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative Analgesic Consumption
Time Frame: 24 hours postoperatively
The opioid consumption via patient controlled analgesia (PCA) in 24 hours postoperatively
24 hours postoperatively

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative Pain Scores
Time Frame: up to 24 hours after surgery
Postoperative pain will be assessed using Numeric Rating Scale (NRS) at 30 mins, and 1, 4, 8, 12, 24 hours after surgery.
up to 24 hours after surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istanbul Medeniyet University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

September 23, 2025

Primary Completion (Estimated)

December 10, 2025

Study Completion (Estimated)

December 31, 2025

Study Registration Dates

First Submitted

July 31, 2025

First Submitted That Met QC Criteria

September 17, 2025

First Posted (Estimated)

September 18, 2025

Study Record Updates

Last Update Posted (Estimated)

September 18, 2025

Last Update Submitted That Met QC Criteria

September 17, 2025

Last Verified

July 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • EOİKB001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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