Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations (MOPs)

April 30, 2026 updated by: Taha Saad Said Hossameldin, Al-Azhar University

Evaluation of Dentoalveolar Changes Following Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations in Deep Bite Cases: A Randomized Clinical Trial

Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Micro-osteoperforations (MOPs) are a new, simple, and minimally invasive technique to accelerate tooth movement. The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increased bone resorption, the catabolic phase of tooth movement, in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement and decrease root resotption.

Study Type

Interventional

Enrollment (Estimated)

18

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Egypt
    • Nasr City
      • Cairo, Nasr City, Egypt, 4434103
        • Recruiting
        • Faculty of Dental Medicine (Boys), Al-Azhar University
        • Contact:
        • Contact:
        • Principal Investigator:
          • Taha S.S Hossameldin, MSc Candidate

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  1. Patients age between 15-25 years.
  2. Patients with overbite ≥ 4 mm.
  3. All permanent teeth erupted (excluding 3rd molars).
  4. No previous orthodontic treatment.
  5. Patients with good oral hygiene and good periodontal health.

Exclusion Criteria:

  1. Skeletal discrepancies.
  2. Missing maxillary anterior teeth or any kind of tooth/root shape anomaly.
  3. Patients with root resorption or impacted canines.
  4. Previous history of orthodontic treatment.
  5. Systemic disease interferes with orthodontic tooth movement.
  6. History of trauma affecting the maxillary incisors.
  7. Poor oral hygiene or periodontally compromised patient.
  8. Endodontically treated upper anterior teeth.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Maxillary incisor intrusion with utility arch assisted with micro-osteoperforations.
Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets with application of micro-osteoperforations above the apices of maxillary incisors.
Procedure: Micro-osteoperforations
Using utility arch with micro-osteoperforations (MOPs). The biologic mechanism behind MOPs is to increase the cytokine expression that leads to increase bone resorption and the catabolic phase of tooth movement in the direction of tooth movement. Transmucosal holes in cortical bone are made to trigger bone remodeling changes for faster tooth movement at the apices above maxillary incisors to evaluate the amount of movement and amount of root resorption.
Other Names:
  • MOPs
Active Comparator: Maxillary incisor intrusion with utility arch without micro-osteoperforations
Using Ricketts utility arch in the maxillary arch inside the molar tubes bypassing premolars and canines to engage inside the four incisors brackets without application of micro-osteoperforations.
Device: Utility arch
Patients will receive utility arch for intrusion of maxillary incisors without micro-osteoperforations.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Amount of root resorption
Time Frame: Up to 6 months or correction of deep bite
Up to 6 months or correction of deep bite
Marginal bone level changes
Time Frame: Up to 6 months or correction of deep bite
Up to 6 months or correction of deep bite

Secondary Outcome Measures

Outcome Measure
Time Frame
Amount of intrusion of maxillary incisors
Time Frame: Up to 6 months or correction of deep bite
Up to 6 months or correction of deep bite

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Al-Azhar University

Investigators

  • Study Director: Hussein N.I Al khalifa, Professor, Vice Dean (Phd), Faculty of Dental medicine (Boys), Al-Azhar University, Cairo, Egypt
  • Study Director: Raafat E. Mohamed, Prof, Head of Department (Phd), Faculty of Dental medicine (Boys), Al-Azhar University, Cairo, Egypt

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

May 1, 2026

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2029

Study Registration Dates

First Submitted

April 24, 2026

First Submitted That Met QC Criteria

April 30, 2026

First Posted (Actual)

May 5, 2026

Study Record Updates

Last Update Posted (Actual)

May 5, 2026

Last Update Submitted That Met QC Criteria

April 30, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 1333/833

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Data will not be shared due to privacy considerations.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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