Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors

Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors: A Comparative Clinical Study

The present study will be directed to evaluate the effect of low-level laser therapy on root resorption during orthodontic intrusion of upper incisors.

Study Overview

• Status: Enrolling by invitation
• Conditions: Root Resorption of Maxillary Incisors
• Intervention / Treatment: Device: gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland); Other: group B

• Study Type: Interventional
• Enrollment (Anticipated): 18
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Naşr, Egypt
    • Al Azhar Univertsity

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 12 years to 16 years (Child)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patients with age range between 12-16 years.

  • Overbite > 40% indicated for maxillary intrusion.
  • Mild to moderate crowding of upper incisors.
  • All permanent teeth erupted (excluding 3rd molars).
  • No previous orthodontic treatment.
  • Good oral hygiene with no previous periodontal surgery

Exclusion Criteria:

• Transverse and/or vertical skeletal dysplasia or craniofacial malformation.

  • Retained primary or missing permanent teeth in the maxillary anterior area, and any kind of tooth/root shape anomaly.
  • Patients with root resorption, impacted canines, or dental anomalies.
  • Poor oral hygiene
  • Present or history of periodontal diseases.
  • Systemic diseases or regular use of medications that could interfere with orthodontic tooth movement.
  • History of trauma affecting the maxillary incisors.
  • Endodontically treated upper anterior teeth.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Experimental group; Will includes 9 patients who will receive intrusive arche after leveling and alignment assisted with laser with wavelength 635 nm, 6.5J/cm2,The laser will be applied to 4 points of application for each tooth two labial and two palatal started immediately after first intrusive wire then at days 3,7,14 and then every 15 day until achievement of the study objectives	Device: gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland); The laser will be applied to 4 points of application for each tooth two labial and two palatal started immediately after first intrusive wire then at days 3,7,14 and then every 15 day until achievement of the study objectives
Active Comparator: Control group; Will includes 9 patients who will receive intrusive arches after leveling and alignment without laser application	Other: group B; Will includes 9 patients who will receive intrusive arches after leveling and alignment without laser application

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
linear amount of root resorption	cone beam computed linear measurements	change in linear root resorption at 4 months
volumetric amount of root resorption	cone beam computed volumetric measurements	change in volumetric root resorption at 4 months

Collaborators and Investigators

• Sponsor: Al-Azhar University

Publications and helpful links

General Publications

• Goel P, Tandon R, Agrawal KK. A comparative study of different intrusion methods and their effect on maxillary incisors. J Oral Biol Craniofac Res. 2014 Sep-Dec;4(3):186-91. doi: 10.1016/j.jobcr.2014.11.007. Epub 2014 Dec 6.

Study record dates

Study Major Dates

• Study Start (Actual): December 15, 2022
• Primary Completion (Anticipated): May 15, 2023
• Study Completion (Anticipated): December 20, 2023

Study Registration Dates

• First Submitted: November 22, 2022
• First Submitted That Met QC Criteria: January 28, 2023
• First Posted (Actual): February 1, 2023

Study Record Updates

• Last Update Posted (Actual): February 1, 2023
• Last Update Submitted That Met QC Criteria: January 28, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Stomatognathic Diseases; Tooth Diseases; Tooth Resorption; Root Resorption
• Other Study ID Numbers: 796/2193

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No