Lower Extremity Mobility for CAI

Effects of Targeted Mobility Interventions at the Ankle Versus Hip on Clinical and Functional Outcomes in Chronic Ankle Instability

This study will be conducted to determine the effect of addition of ankle mobility versus hip mobility exercises to traditional rehabilitation to patients with chronic ankle instability. the main purpose is to answer the following question:

• out of these interventions which would better improve lower limb flexibility, range of motion, severity of functional instability and dynamic postural control?

Researcher will compare between ankle mobility versus hip mobility exercises

Participants will be allocated in 2 experimental groups:

• group A will include 20 patients receiving conventional physiotherapy in addition to ankle mobility exercises
• group B will include 20 patients receiving conventional physiotherapy in addition to hip mobility exercises

Patients will receive 3 sessions per week for 6 weeks in a physiotherapy outpatient facility for both groups

Study Overview

• Status: Not yet recruiting
• Conditions: Chronic Ankle Instability, CAI
• Intervention / Treatment: Other: traditional rehabilitation for Chronic Ankle Instability; Other: Ankle mobility exercises; Other: Hip mobility exercises

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Amal Mounir Mohamed; Phone Number: +201141099494; Email: amalmunir26@gmail.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Adults (18-30 years old) with chronic ankle instability
• Patient's Body mass index (BMI) will range from 18.5- 29.9 kg/m2
• A history of at least one ankle sprain with the initial sprain occurring 12 months prior to study
• Most recent injury 3 months prior to start of treatment with at least one day of interrupted desired physical activity and associated inflammatory symptoms (pain, swelling, etc.).
• A history of previous giving way and/or recurrent sprain, and/or feeling of instability to injured ankle.
• Cumberland Ankle Instability Tool: score of ≤ 24.

Exclusion Criteria:

• Other lower extremity injury surgery 6 months before testing
• Patient suffered an acute sprain in the previous 6 weeks to the start of the study.
• History of neuromuscular disorders.
• Systemic diseases that affect balance.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Group A; 20 patients (10 males and 10 females) will receive ankle mobility exercises and traditional physiotherapy program	Other: traditional rehabilitation for Chronic Ankle Instability; Ankle muscles strengthening exercises; balance training; Other: Ankle mobility exercises; 9 ankle mobility exercises including: ankle pumps, ankle circles, forward lunges, plantarflexion stretch, calf stretch, squat with overhead reach, heel drops on step, ankle flexion with band and scoops
Experimental: Group B; 20 patients (10 males and 10 females) will receive hip mobility exercises and traditional physiotherapy program	Other: traditional rehabilitation for Chronic Ankle Instability; Ankle muscles strengthening exercises; balance training; Other: Hip mobility exercises; 8 hip mobility exercises including: 90/90 hip stretch, frog stretch, world's greatest stretch, banded hamstring stretch, backward lunges, butterfly, pigeon stretch and banded hip stretch.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
lower limb flexibility	measure the lower trunk and lower extremity flexibility with modified sit and reach test, sideways split and single legged knee bend test	6 weeks
Range of motion	Hip flexion and extension range of motion Ankle dorsiflexion and plantarflexion range of motion	6 weeks
Dynamic postural control	using the modified star excursion balance test	6 weeks
severity of chronic ankle instability	using the Arabic version of the Cumberland Ankle Instability Tool, a tool used to describe the severity of chronic ankle instability, with the highest possible score is: 30 and the lowest possible score is: 0 Higher scores indicate better ankle stability, while lower scores indicate higher severity of functional instability	6 weeks

Collaborators and Investigators

• Sponsor: Cairo University

Study record dates

Study Major Dates

• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): October 1, 2026

Study Registration Dates

• First Submitted: May 7, 2026
• First Submitted That Met QC Criteria: May 7, 2026
• First Posted (Actual): May 13, 2026

Study Record Updates

• Last Update Posted (Actual): May 18, 2026
• Last Update Submitted That Met QC Criteria: May 15, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: Mobility training for CAI

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No