- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07612969
Comparing The Effect of Proprioceptive Neuromuscular Facilitation (PNF) When Coupled With Dry Needling (DN), Acupuncture (AN) or Sham Needling (SN) on Knee Range of Motion (ROM), Jump Height and Unipedal Balance
May 25, 2026 updated by: Mohamad Karam
Comparing the Effect of Dry Needle, Acupuncture and Sham Needling When Added to Muscle Release Technique on Knee Range of Motion, Unipedal Balance and Jump Height in Active Men: A Randomized Control Single Blinded Study
Muscle tightness was found to increase injury risks.
Muscle relaese techniques and needling were known to reduce muscle tightness, their specific influence on functional muscle performance remains inconclusive.
We hypothesized that (1) combining needling modalities with muscle release techniques (PNF) would significantly improve range of motion, unipedal balance, and jump height compared to a sham intervention; and (2) the specific combination of dry needling and PNF would demonstrate superior functional progression compared to the acupuncture and PNF protocol over a 5-week timeframe.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Active men with confirmed hamstring and quadriceps tightness in both legs were included.
Unipedal balance and jump height were evaluated using Kinetisense®.
Subjects were randomly assigned to 3 groups: Group1: Dry needling; Group2: Acupuncture and Group3: Sham needling.
All subjects also received PNF application after needling modality.
Each participant received 1 session per week for 5 weeks.
Study Type
Interventional
Enrollment (Actual)
65
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Beirut
-
Beirut, Beirut, Lebanon
- Faculty of Medicine, Institute of Physiotherapy, Saint Joseph University of Beirut
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
- moderately active men (Perform at least 60 min of any sport activity on at least 3 days per week)
- aged between 18 and 28 years old
- having muscular tightness in both hamstrings and quadriceps muscles in both lower limbs
Exclusion Criteria:
- men who received any surgical, dry needling or acupuncture treatment in the last 6 months prior to the experimentation.
- Participants who had suffered from any injuries at the level of the hips, knees or ankles in the 12 months before the study.
- participants under anticoagulant medications or suffering from bleeding disorders.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Dry needling associated to Proprioceptive Neuromuscular Facilitation
|
This study explore the combination of Proprioceptive Neuromuscular Facilitation with 3 types of needling technique and their effect on Range of motion, unipedal balance and Jump height
Other Names:
|
|
Experimental: Acupuncture associated to Proprioceptive Neuromuscular Facilitation
|
This study explore the combination of Proprioceptive Neuromuscular Facilitation with 3 types of needling technique and their effect on Range of motion, unipedal balance and Jump height
Other Names:
|
|
Experimental: Sham needling associated to Proprioceptive Neuromuscular Facilitation
|
This study explore the combination of Proprioceptive Neuromuscular Facilitation with 3 types of needling technique and their effect on Range of motion, unipedal balance and Jump height
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Range of motion
Time Frame: 1 week before protocol application and 5 weeks after
|
Knee range of motion was evaluated using a Goniometer
|
1 week before protocol application and 5 weeks after
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Jump height
Time Frame: 1 week prior to the protocol application and 5 weeks after
|
was evaluated using Kinetisence
|
1 week prior to the protocol application and 5 weeks after
|
|
Unipedal balance
Time Frame: 1 week prior to the protocol and 5 weeks after
|
Was evaluated using Kinetisense
|
1 week prior to the protocol and 5 weeks after
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Kuzdzal A, Trybulski R, Muracki J, Klich S, Clemente FM, Kawczynski A. Dry Needling in Sports and Sport Recovery: A Systematic Review with an Evidence Gap Map. Sports Med. 2025 Apr;55(4):811-844. doi: 10.1007/s40279-025-02175-9. Epub 2025 Feb 10.
- Forogh B, Ghaseminejad Raeini A, Jebeli Fard R, Mirghaderi P, Nakhostin-Ansari A, Nakhostin-Ansari N, Bahari H, Hoveidaei AH. Efficacy of trigger point dry needling on pain and function of the hip joint: a systematic review of randomized clinical trials. Acupunct Med. 2024 Apr;42(2):63-75. doi: 10.1177/09645284231207870. Epub 2023 Dec 27.
- Zhu F, Chen Y, Zhu Y, Bai Z, Yan H. Acupuncture Therapy for Extremity Musculoskeletal Pain: A Clinically Focused Evidence Synthesis with Therapeutic Implications. J Pain Res. 2025 Oct 24;18:5541-5554. doi: 10.2147/JPR.S551446. eCollection 2025.
- Reiner MM, Tilp M, Nakamura M, Konrad A. Is muscle stiffness a determinant for range of motion in the leg muscles? Biol Sport. 2024 Mar;41(2):115-121. doi: 10.5114/biolsport.2024.131821. Epub 2023 Jun 10.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 16, 2023
Primary Completion (Actual)
February 20, 2023
Study Completion (Actual)
February 27, 2023
Study Registration Dates
First Submitted
May 17, 2026
First Submitted That Met QC Criteria
May 25, 2026
First Posted (Actual)
May 29, 2026
Study Record Updates
Last Update Posted (Actual)
May 29, 2026
Last Update Submitted That Met QC Criteria
May 25, 2026
Last Verified
January 1, 2023
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Motor Activity
- Movement
- Musculoskeletal Physiological Phenomena
- Musculoskeletal and Neural Physiological Phenomena
- Therapeutics
- Complementary Therapies
- Physical Therapy Modalities
- Patient Care
- Exercise Therapy
- Rehabilitation
- Aftercare
- Continuity of Patient Care
- Exercise
- salicylhydroxamic acid
- Dry Needling
- Acupuncture Therapy
- Muscle Stretching Exercises
Other Study ID Numbers
- USJ-2023-10
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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