Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes (ELECTRA)

The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.

Study Overview

• Status: Not yet recruiting
• Conditions: Healthy Subjects
• Intervention / Treatment: Device: Magnetic Resonance Imaging (MRI) examination

• Study Type: Interventional
• Enrollment (Estimated): 120
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Marc BRAUN, MD, PhD; Phone Number: +33 0383157823; Email: m.braun@chru-nancy.fr
• Study Contact Backup: Name: Guillaume DROUOT, PhD; Phone Number: +33 0383157666; Email: g.drouot@chru-nancy.fr

Study Locations

• France
  • Strasbourg, France, 67085
    • Institut de Physique Biologique
    • Contact: Paulo LOUREIRO DE SOUSA, PhD; Phone Number: +33 0368854076; Email: ploureiro@unistra.fr
    • Sub-Investigator: Jack FOUCHER, MD, PhD
  • CHRU de Nancy
    • Vandœuvre-lès-Nancy, CHRU de Nancy, France, 54511
      • CHRU Nancy
      • Contact: Guillaume DROUOT, PhD; Phone Number: +33 0383157666; Email: g.drouot@chru-nancy.fr
      • Principal Investigator: Marc BRAUN, MD, PhD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Person aged between 6 and 12, 20 and 40 years or aged 70 years and above
• Person affiliated with a social security scheme or beneficiary of such a scheme
• Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form

Exclusion Criteria:

• Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device
• Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters
• Pregnant woman, woman in labor, or breastfeeding mother
• Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Children between 6 and 12 years old	Device: Magnetic Resonance Imaging (MRI) examination; MRI examination of the head and neck, and torso for the measurement of electrical properties
Experimental: Adults between 20 and 40 years old	Device: Magnetic Resonance Imaging (MRI) examination; MRI examination of the head and neck, and torso for the measurement of electrical properties
Experimental: Adults aged 70 and above	Device: Magnetic Resonance Imaging (MRI) examination; MRI examination of the head and neck, and torso for the measurement of electrical properties

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Conductivity in S/m at the head level in subjects aged 6 to 12 years	Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years	Baseline (J0)
Conductivity in S/m at the head level in subjects aged 20 to 40 years	Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years	Baseline (J0)
Conductivity in S/m at the head level in subjects aged 70 and above	Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above	Baseline (J0)
Conductivity in S/m at the neck level in subjects aged 6 to 12 years	Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years	Baseline (J0)
Conductivity in S/m at the neck level in subjects aged 20 to 40 years	Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 20 to 40 years	Baseline (J0)
Conductivity in S/m at the neck level in subjects aged 70 and above	Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 70 and above	Baseline (J0)
Conductivity in S/m at the torso level in subjects aged 6 to 12 years	Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 6 to 12 years	Baseline (J0)
Conductivity in S/m at the torso level in subjects aged 20 to 40 years	Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 20 to 40 years	Baseline (J0)
Conductivity in S/m at the torso level in subjects aged 70 and above	Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 70 and above	Baseline (J0)

Collaborators and Investigators

• Sponsor: Central Hospital, Nancy, France

Study record dates

Study Major Dates

• Study Start (Estimated): April 4, 2026
• Primary Completion (Estimated): February 2, 2029
• Study Completion (Estimated): February 2, 2029

Study Registration Dates

• First Submitted: February 10, 2026
• First Submitted That Met QC Criteria: February 10, 2026
• First Posted (Actual): February 17, 2026

Study Record Updates

• Last Update Posted (Actual): April 8, 2026
• Last Update Submitted That Met QC Criteria: April 2, 2026
• Last Verified: April 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Diagnostic Techniques and Procedures; Diagnosis; Tomography; Diagnostic Imaging; Magnetic Resonance Imaging; Physical Examination
• Other Study ID Numbers: 2023-A01227-38

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No