Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults (CAPFISOBEANZ)

May 22, 2026 updated by: Istituto Auxologico Italiano

Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people.

To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

160

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Italy
      • Oggebbio, Italy, 28824
        • Recruiting
        • Istituto Auxologico Italiano IRCCS, Site Piancavallo
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Hospitalized obese elderly following a 3-week integrated metabolic rehabilitation program

+ Normal weight elderly attending correct lifestyle program in their home town

Description

Obese elderly:

Inclusion Criteria:

  • Both sexes
  • Body Mass Index > 35 kg/m2
  • Age > 65 years
  • Hospitalized for a 3-week integrated metabolic rehabilitation program

Exclusion Criteria:

  • Absence of signed informed consent

Normal weight elderly:

Inclusion Criteria:

  • Both sexes
  • Body Mass Index 20-25 kg/m2
  • Age > 65 years
  • Attendance of healthy lifestyle program in their home town

Exclusion Criteria:

  • Absence of signed informed consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Obese elderly
Obese men and women of 65 years and older
Other: Fitness tests and questionnaires
Anthropometric measurements, physical fitness tests and daily life questionnaires
Normal weight elderly
Normal weight men and women of 65 years and older
Other: Fitness tests and questionnaires
Anthropometric measurements, physical fitness tests and daily life questionnaires

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Fat mass
Time Frame: Baseline
Fat mass as assessed by bioelectrical impedance
Baseline
Lean mass
Time Frame: Baseline
Lean mass as assessed by bioelectrical impedance
Baseline
Barthel Index
Time Frame: Baseline
Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100
Baseline
Handgrip test
Time Frame: Baseline
Score in kilograms (kg) using a hand dynamometer
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Istituto Auxologico Italiano

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 29, 2025

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2026

Study Registration Dates

First Submitted

May 22, 2026

First Submitted That Met QC Criteria

May 22, 2026

First Posted (Actual)

May 29, 2026

Study Record Updates

Last Update Posted (Actual)

May 29, 2026

Last Update Submitted That Met QC Criteria

May 22, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 01C514

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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