Efficiency of Carbon Dioxide Fractional Laser in Skin Resurfacing

Andrej Petrov, Andrej Petrov

Abstract

Aim: The aim of the study was to confirm the efficiency and safety of the fractional CO2 laser in skin renewal and to check the possibility of having a synergistic effect in patients who besides carbon dioxide laser are treated with PRP (platelet-rich plasma) too.

Material and methods: The first group (Examined Group 1 or EG1) included 107 patients treated with fractional CO2 laser (Lutronic eCO2) as mono-therapy. The second group (Control Group or CG) covered 100 patients treated with neither laser nor plasma in the same period but subjected to local therapy with drugs or other physio-procedures under the existing protocols for treatment of certain diseases. The third group (Examined Group 2 or EG2) treated 25 patients with combined therapy of CO2 laser and PRP in the treatment of facial rejuvenation or treatment of acne scars.

Results: Patient's satisfaction, in general, is significantly greater in both examined groups (EG1 and EG2) (p < 0.001). It was found the significant difference between control and examined group from the treatment in acne scar (Fisher exact two tailed p < 0.001). Patients satisfaction with the treatment effect in rejuvenation of the skin is significant (χ2 = 39.41; df = 4; p < 0.001). But, patients satisfaction from the treatment with HPV on the skin was significantly lower in examined group (treated with laser), p = 0.0002.

Conclusion: Multifunctional fractional carbon dioxide laser used in treatment of patients with acne and pigmentation from acne, as well as in the treatment of scars from different backgrounds, is an effective and safe method that causes statistically significant better effect of the treatment, greater patients' satisfaction, minimal side effects and statistically better response to the therapy, according to assessments by the patient and the therapist.

Keywords: CO2; laser; resurfacing; skin; synergistic effect.

Figures

Figure 1
Figure 1
Effect of the treatment between 3 groups- patients satisfaction assessment.
Figure 2
Figure 2
Patients satisfaction from the treatment in patients with HPV on the skin.
Figure 3
Figure 3
a) Patient with acne scars before treatment with CO2 laser; b) The same patient from the previous picture after 4 treatments with CO2 laser.
Figure 4
Figure 4
a) Patient for rejuvenation before treatment; b) Same patient from the previous picture after 3 sessions of CO2 laser.
Figure 5
Figure 5
a) Patient treated with plasma and CO2 laser before treatment; b) the Same patient from picture 7, after 3 sessions of CO2 laser and 2 sessions of PRP, during lip augmentation.

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