Clinical Implementation and Evaluation of Three Implementation Interventions for a Family-Oriented Care for Children of Mentally Ill Parents (ci-chimps): Study Protocol for a Randomized Controlled Multicenter Trial

Carolin Laser, Anna Modarressi, Bjørg Eva Skogøy, Andrea Reupert, Anne Daubmann, Alexandra Höller, Antonia Zapf, Silke Pawils, Svenja Taubner, Sibylle Winter, Darryl Maybery, Silke Wiegand-Grefe, Carolin Laser, Anna Modarressi, Bjørg Eva Skogøy, Andrea Reupert, Anne Daubmann, Alexandra Höller, Antonia Zapf, Silke Pawils, Svenja Taubner, Sibylle Winter, Darryl Maybery, Silke Wiegand-Grefe

Abstract

Background: In Germany, approximately three million children under the age of eighteen have a mentally ill parent. These children are at an increased risk of developing a mental illness themselves (1) as well as a physical illness (2). While research has identified numerous evidence-based family-oriented interventions, little is known about how to implement such interventions effectively and efficiently in clinical practice in Germany. This implementation study (ci-chimps) evaluates three clinical implementation projects with three different implementation interventions for the optimal implementation of the tailored family-oriented preventive and therapeutic interventions in the CHIMPS-NET (children of mentally ill parents-research network) with an implementation model for children of mentally ill parents.

Methods: A two-group randomized controlled multicenter trial will examine changes in family-oriented practice and aspects of implementation at baseline as well as at 12- and 24-months follow-up. The CHIMPS-Network consists of 20 clinical centers. The centers in the intervention group receive the support of all of the three implementation interventions: (1) optimal pathways to care, (2) education and a training program for professionals, and (3) systematic screening for children. The centers in the control group do not receive this specific implementation support.

Discussion: While we know that children of mentally ill parents are an important target group to be addressed by preventive and therapeutic interventions, there is often a lack of structured implementation of family-oriented interventions in clinical practice in Germany. Using a randomized controlled multicenter trial design with a large and wide-ranging sample (clinics for adult psychiatry and clinics for child and adolescent psychiatry, university clinics and clinics at the real health care) will provide a robust understanding of implementing family-oriented changes in German clinical practice.

Trial registration: The CHIMPS-NET-study was registered with the German Clinical Trials Register on 2019-12-19 (DRKS00020380) and with Clinical Trials on 2020-4-30 (NCT04369625), the ci-chimps-study was registered with the German Clinical Trials Register (DRKS00026217) on 2021-08-27, the Clinical Trials registration is in review process.

Keywords: children of mentally ill parents; family implementation interventions; implementation research; multicenter trial; randomized controlled trial.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Copyright © 2022 Laser, Modarressi, Skogøy, Reupert, Daubmann, Höller, Zapf, Pawils, Taubner, Winter, Maybery and Wiegand-Grefe.

Figures

Figure 1
Figure 1
The CHIMPS-NET Implementation Model [based on (22) and first published (25)] for the health care for children and their mentally ill parents.
Figure 2
Figure 2
Study design.

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