Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives

Y Rolland, S Czerwinski, G Abellan Van Kan, J E Morley, M Cesari, G Onder, J Woo, R Baumgartner, F Pillard, Y Boirie, W M C Chumlea, B Vellas, Y Rolland, S Czerwinski, G Abellan Van Kan, J E Morley, M Cesari, G Onder, J Woo, R Baumgartner, F Pillard, Y Boirie, W M C Chumlea, B Vellas

Abstract

Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.

Figures

Figure 1
Figure 1
Sarcopenia and the disability process
Figure 2
Figure 2
Relationship between muscle mass, muscle strength and physical performances

Source: PubMed

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