DSM-IV diagnoses and obstructive sleep apnea in children before and 1 year after adenotonsillectomy

Abstract

Objective: Obstructive sleep apnea, a common indication for adenotonsillectomy in children, has been linked to behavioral morbidity. We assessed psychiatric diagnoses in children before and after adenotonsillectomy and examined whether baseline sleep apnea predicted improvement after surgery.

Method: Subjects of this prospective cohort study were children ages 5.0 to 12.9 years old who had been scheduled for adenotonsillectomy (n = 79) or care for unrelated surgical conditions (n = 27, among whom 13 had surgery after baseline assessment). Before intervention and 1 year later, subjects underwent structured diagnostic interviews and polysomnography. The main outcome measure was frequency of DSM-IV attention and disruptive behavior disorder diagnoses at baseline and follow-up.

Results: At baseline, attention and disruptive behavior disorders were diagnosed in 36.7% of adenotonsillectomy subjects and 11.1% of controls (p < .05); attention-deficit/hyperactivity disorder was found in 27.8% and 7.4%, respectively (p < .05). One year later, group differences were nonsignificant; attention and disruptive behavior disorders were diagnosed in only 23.1% (p < .01), and 50% of subjects with baseline attention-deficit/hyperactivity disorder no longer met diagnostic criteria. Obstructive sleep apnea on polysomnography at baseline did not predict concurrent psychiatric morbidity or later improvement.

Conclusions: Attention and disruptive behavior disorders, diagnosed by DSM-IV criteria, were more common before clinically indicated adenotonsillectomy than 1 year later. Surgery may be associated with reduced morbidity, even among subjects lacking polysomnographic evidence of obstructive sleep apnea.

Figures

Figure 1. Psychiatric Ratings at Baseline and Follow-Up in Three Groups of Subjects

Statistical associations shown here reflect effect slices (univariate analyses based on adjusted means, equivalent to paired student’s t-tests) showing the significance of change in subgroups of children with or without OSA from pre-op to post-op assessment. There were no significant differences between OSA subgroups at baseline or at follow-up. DBDRS = Disruptive Behavior Disorders Rating Scale. * p

Figure 1. Psychiatric Ratings at Baseline and Follow-Up in Three Groups of Subjects

Statistical associations shown here reflect effect slices (univariate analyses based on adjusted means, equivalent to paired student’s t-tests) showing the significance of change in subgroups of children with or without OSA from pre-op to post-op assessment. There were no significant differences between OSA subgroups at baseline or at follow-up. DBDRS = Disruptive Behavior Disorders Rating Scale. * p