Health-related quality of life in type 2 diabetic patients

Amer H Al-Shehri, Attia Z Taha, Ahmed A Bahnassy, Mohammad Salah, Amer H Al-Shehri, Attia Z Taha, Ahmed A Bahnassy, Mohammad Salah

Abstract

Background and objectives: Health-related quality of life (HRQOL) is an important health outcome, representing one of the most important goals of all health interventions. The objectives of this study were to determine HRQOL and the factors affecting it in type 2 diabetic patients.

Patients and methods: This cross-sectional study was conducted in five primary health care (PHC) centers in the Al-Khobar area. From a random sample of 225 type 2 diabetic patients, 216 patients were included in the study along with 216 age- , sex- and nationality-matched controls. Nine patients refused to participate. Type 2 diabetic patients and controls were interviewed with the translated Arabic SF-12 questionnaire.

Results: The mean ages were 50.0A+/-10.0 years for cases and of 49.3+/-10.3 years for controls (P=.526). Type 2 diabetic patients had lower socioeconomic status and educational level than controls. Obesity was significantly higher in diabetics than controls. HRQOL in type 2 diabetic patients was significantly lower than controls. The mean physical component score was 41.3+/-8.9 for cases vs. 47.5+/-9.5 for controls (P<.001), and the mean mental component score 47.8+/-9.1 in cases vs. 51.5+/-9.4 in controls (P<.001). HRQOL was significantly lower in females than males (P<.001). HRQOL was impaired in uncontrolled patients (fasting plasma glucose [FPG]>130 mg/dL) in comparison with controlled patients (FPG</=130 mg/dL) (P<.05).

Conclusions: HRQOL was lower in type 2 diabetic patients than controls and was affected by many factors. Females had lower HRQOL than males, possibly because of a higher incidence of obesity. Uncontrolled diabetic patients had a lower HRQOL than controlled diabetics. Improving HRQOL in diabetic patients is important.

Figures

https://www.ncbi.nlm.nih.gov/pmc/articles/instance/6074492/bin/asm-5-352f1.jpg
https://www.ncbi.nlm.nih.gov/pmc/articles/instance/6074492/bin/asm-5-352f2.jpg

References

    1. El-Hazmi M, Warsy A, Al-Swailem A, Al-Swailem A, Sulaimani R. Diabetes mellitus as a health problem in Saudi Arabia. East Mediterr Health J. 1998;4(1):58–67.
    1. Testa M. Quality-of-Life Assessment in Diabetes Research: Interpreting the Magnitude and Meaning of Treatment Effects. Diabetes Spectrum. 2000;13:29.
    1. Polonsky W. Understanding and assessing diabetes-specific quality of life. Diabetes Spectr. 2000;13:36.
    1. Rubin R. Diabetes and quality of life. Diabetes Spectr. 2000;13:21.
    1. Luscomble F. Health-related quality of life measurement in type 2 diabetes. Value in Health. 2000;3(1):15–28.
    1. Franciosi M, Pellegrini F, De Berardis G, Belfiglio M, Cavaliere D, Nardo B, et al. The impact of blood glucose self-monitoring on metabolic control and quality of life in type 2 diabetic patients. Diabetes Care. 2001;24(11):1870–1877.
    1. Palitzsch K, Volmer T, Abrams C, Schoelmerich J. The impact of diabetes risk factors on the quality of life of patients with type 2 diabetes. Diabetes. 2000;49(5):390.
    1. Ware JE, Kos M, Keller SD. SF-12: How to score the SF-12 Physical and Mental Health Summary Scales. 3rd Ed. Lincoln: Quality Metric Inc; 1998. pp. 29–59.
    1. EL-Hazmi M, Warsy AS, Al Swilem AR, AL-Swilem AM, AL-Sulimanni R, AL-Meshari A. Diabetes mellitus and impaired glucose tolerance in Saudi Arabia. Ann Saudi Med. 1996;16(4):381–385.
    1. Daniel W. Biostatistics: A Foundation for Analysis in the Health Sciences. 5th Ed. New York: John Wiley & Sons, Inc; 1991. pp. 154–158.
    1. Ware J. SF-36 Health survey update. Spine. 2000;25(24):3130–3139.
    1. Ware J, Kosinski M. SF-36: Physical and Mental Health Summary Scales: Manual for Users of Version 1. 2nd Ed. Lincoln. RI: Quality Metric Inc; 2001.
    1. Gandek B, Ware J, Aaronson N, Apolone, Bjorner J, Brazier J, et al. Cross-validation of item selection and scoring for the SF-12 health survey in nine countries_results from the medical outcomes study. J Clin Epidemiol. 1998;51(11):1171–1178.
    1. ADA (American Diabetes Association) Guidelines for glycemic control in people with diabetes. Reprinted with permission from the American Diabetes Association. Clinical practice recommendations 2001. Diabetes Care. 2001;24(1):S34.
    1. Hill-Briggs F, Gary T, Hill M, Bone L, Brancati F. Health-related quality of life in urban African- Americans with type 2 diabetes. J Gen Intern Med. 2002;17(6):412–9.
    1. Fontaine KR, Bartlett SJ, Barofsky I. Health-related quality of life among obese persons seeking and not currently seeking treatment. Int J Eat Disord. 2000;27(1):101–5.
    1. Mazzeo R, Tanaka H. Exercise prescription for the elderly current recommendations. Sports Med. 2001;31(11):809–818.
    1. SPSS-Win. SPSS Release 10.0.1. USA: 1999. Statistical package for social sciences (computer program)
    1. Al-Arabi A. Dissertation. Al-Khobar, KSA: King Faisal niversity; 1996. Assessment of Diabetes-Related Distress and Psychosocial Adjustment.
    1. Larsson D, Lager I, Nilsson P. Socio-economic characteristics and quality of life in diabetes mellitus- relation to metabolic control. Scand J Public Health. 1999;2:101–105.
    1. Hanninen J, Takala J, Keinanen-Kiukaanniemi S. Quality of life in NIDDM patients assessed with the SF-20 questionnaire. Diabetes Res Clin Pract. 1998;42(1):17–27.
    1. Murray F. Body mass index and quality of life in a survey of primary care patients. J Fam Pract. 2000;49(8):734–737.
    1. Pfalzgraf A. The relationship of diabetes symptoms and health-related quality of life. Value in Health. 2001;4(2):58.
    1. Hemingway H, Nicholson A, Marmot M. The Impact of Socioeconomic Status on Health Functioning as Assessed by the SF-36 Questionnaire: The Whitehall II Study. American
    1. Lloyd A, Sawyer W, Hopkinson P. Impact of long-term complications on quality of life in patients with type 2 Diabetes not using insulin. Value in Health. 2001;4(5):392–400.
    1. Glasgow RE, Ruggiero L, Eakin EG, Dryfoos J, Chobanian L. Quality of life and associated characteristics in a large national sample of adults with diabetes. Diabetes Care. 1997;20(4):562–567.
    1. Kirk A, Higgins L, Hughes A, Fishert B, Mutrie N, Hillis S, et al. A randomized, controlled trial to study the effect of exercise consultation on the promotion of physical activity in people with Type 2 diabetes: a pilot study. Diabetes UK Diabetes Med. 2001;18:877–882.
    1. Goddijn P, Bilo H, Feskens E, Groenier K, Zees K, Jong B. Longitudenal study on glycemic control and quality of life in patients with type 2 diabetes mellitus referred for intensified control. Br Diabetic Assoc Diabetic Med. 1999;16:23–30.
    1. Cheng A, Tsui E, Hanely A, Zinman B. Developing a quality of life measure for Chinese patients with diabetes. Diabetes Res Clin Pract. 1999;46:259–267.
    1. Lean M, Han T, Seidell J. Impairment of health and quality of life using new US federal guidelines for the identification of obesity. Arch Intern Med. 1999;159(8):837–843.
    1. Sturm R, Wells KB. Does obesity contribute as much to morbidity as poverty or smoking? Public Health. 2001;115(3):229–235.
    1. Smide B, Lukwale J, Msoka A, Wikblad K. Self-reported health and glycaemic control in Tanzanian and Swedish diabetic patients. J Adv Nurs. 2002;37(2):182–191.
    1. De Visser C, Bilo H, Groenier K, De Visser W, De Jong B. The influence of cardiovascular disease on quality of life in type 2 diabetics. Quality Life Res. 2002;11:249–261.
    1. Davis T, Clifford R, Davis W. Effect of insulin therapy on quality of life in type 2 diabetes mellitus: The Fremantle Diabetes Study. Diabetes Res Clin Pract. 2001;52:63–71.
    1. Hänninen J, Takala J, Nen-Kiukaanniemi S. Good continuity of care may improve quality of life in Type 2 diabetes. Diabetes Res Clin Pract. 2001;51:21–27.

Source: PubMed

Sponsors and Collaborators

Medical Conditions

Drug Interventions

3
Subscribe