Assessment of Nutritional Status of Infants Living in Arsenic-Contaminated Areas in Bangladesh and Its Association with Arsenic Exposure

Abul Hasnat Milton, John Attia, Mohammad Alauddin, Mark McEvoy, Patrick McElduff, Sumaira Hussain, Ayesha Akhter, Shahnaz Akter, M Munirul Islam, A M Shamsir Ahmed, Vasu Iyengar, Md Rafiqul Islam, Abul Hasnat Milton, John Attia, Mohammad Alauddin, Mark McEvoy, Patrick McElduff, Sumaira Hussain, Ayesha Akhter, Shahnaz Akter, M Munirul Islam, A M Shamsir Ahmed, Vasu Iyengar, Md Rafiqul Islam

Abstract

Data is scarce on early life exposure to arsenic and its association with malnutrition during infancy. This study followed the nutritional status of a cohort of 120 infants from birth to 9 months of age in an arsenic contaminated area in Bangladesh. Anthropometric data was collected at 3, 6 and 9 months of the infant's age for nutritional assessment whereas arsenic exposure level was assessed via tube well drinking water arsenic concentration at the initiation of the study. Weight and height measurements were converted to Z-scores of weight for age (WAZ-underweight), height for age (HAZ-stunting), weight for height (WHZ-wasting) for children by comparing with WHO growth standard. Arsenic exposure levels were categorized as <50 μg/L and ≥50 μg/L. Stunting rates (<-2 SD) were 10% at 3 months and 44% at both 6 and 9 months. Wasting rates (<-2 SD) were 23.3% at 3 months and underweight rates (<-2 SD) were 25% and 10% at 3 and 6 months of age, respectively. There was a significant association of stunting with household drinking water arsenic exposure ≥50 μg/L at age of 9 months (p = 0.009). Except for stunting at 9 months of age, we did not find any significant changes in other nutritional indices over time or with levels of household arsenic exposure in this study. Our study suggests no association between household arsenic exposure and under-nutrition during infancy; with limiting factors being small sample size and short follow-up. Difference in stunting at 9 months by arsenic exposure at ≥50 μg/L might be a statistical incongruity. Further longitudinal studies are warranted to establish any association.

Keywords: Bangladesh; arsenic; children; drinking water; infants; malnutrition; stunting; underweight; wasting.

Conflict of interest statement

The authors declare no conflict of interest.

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