Meta-trial of awake prone positioning with nasal high flow therapy: Invitation to join a pandemic collaborative research effort

Jie Li, Ivan Pavlov, John G Laffey, Oriol Roca, Sara Mirza, Yonatan Perez, Bairbre McNicholas, David Cosgrave, David Vines, Elsa Tavernier, Stephan Ehrmann, Jie Li, Ivan Pavlov, John G Laffey, Oriol Roca, Sara Mirza, Yonatan Perez, Bairbre McNicholas, David Cosgrave, David Vines, Elsa Tavernier, Stephan Ehrmann

No abstract available

Keywords: Acute respiratory distress syndrome; COVID-19 [MeSH]; Meta-analysis [MeSH]; Pandemics [MeSH]; Research design [MeSH].

Conflict of interest statement

Declaration of Competing Interest JL discloses research support from Fisher & Paykel Healthcare for another research project. IP has been a speaker for Fisher & Pakyel Healthcare within the last 3 years. All compensation was paid to the charitable foundation at the hospital where he works, and he did not personally receive any compensation. OR provides consultancy to Hamilton Medical but he did not receieved any personal fee. All compensations were received by the Institute of Research of his Institution. He received speaker fees by Air Liquide. SE received unrestricted research grants, travel fee reimbursements and speaker fees from Fisher & Paykel Healthcare, consulting fees from La Diffusion Technique Française, consulting fees and unrestricted research grants from Aerogen Ltd., and an unrestricted research grant from Hamilton medical. Other authors have no conflict of interest to declare.

References

    1. Phua J., Weng L., Ling L., Egi M., Lim C.M., Divatia J.V., et al. Intensive care management of coronarvirus disease 2019 (COVID-19): challenges and recommendations. Lancet Respir Med. 2020;8:506–517.
    1. Baden L.R., Rubin E.J., Morrissey S., Farrar J.J., Drazen J.M. We can do better — improving outcomes in the midst of an emergency. N Engl J Med. 2017;377:1482–1484.
    1. Ivie R.M.J., Vail E.A., Wunsch H., Goldklang M.P., Fowler R., Moitra V.K. Patient eligibility for randomized controlled trials in critical care medicine: an international two-center observational study. Crit Care Med. 2017;45:216–224.
    1. Rishu A.H., Marinoff N., Julien L., Dumitrascu M., Marten N., Eggertson S., et al. Time required to initiate outbreak and pandemic observational research. J Crit Care. 2017;40:7–10.
    1. Burns K.E.A., Rizvi L., Tan W., Marshall J.C., Pope K. Participation of ICUs in critical care pandemic research: a province wide, cross-sectional survey. Crit Care Med. 2013;41:1009–1016.
    1. Bellani G., Laffey J.G., Pham T., Fan E., Brochard L., Esteban A., et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315:788–800.
    1. Munshi L., Del Sorbo L., Adhikari N.K.J., Hodgson C.L., Wunsch H., Meade M.O., et al. Prone position for acute respiratory distress syndrome. A systematic review and meta-analysis. Ann Am Thorac Soc. 2017;14:S280–S288.
    1. Tavernier E., Trinquart L., Giraudeau B. Finding alternatives to the dogma of power based sample size calculation: is a fixed sample size prospective meta-experiment a potential alternative? Plos One. 2016;11
    1. Simonsen L., Higgs E., Taylor R.J. Clinical research networks are key to accurate and timely assessment of pandemic clinical severity. Lancet Glob Health. 2018;6:e956–e957.
    1. Memoli M.J. Pandemic research in the ICU: always be prepared. Crit Care Med. 2013;41:1147–1148.

Source: PubMed

Sponsors and Collaborators

Medical Conditions

Drug Interventions

3
Subscribe