Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction

Gökmen Sukgen, Aşkı Ellibeş Kaya, Ebru Karagün, Eray Çalışkan, Gökmen Sukgen, Aşkı Ellibeş Kaya, Ebru Karagün, Eray Çalışkan

Abstract

Objective: To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, and genital perception in women with sexual dysfunction.

Materials and methods: Four sessions of PRP were administered to the anterior vaginal wall of 52 female patients with sexual dysfunction and orgasmic disorder [Female Sexual Function Index (FSFI) total score ≤26 orgasmic subdomain score ≤3.75]. Prior to the PRP administrations in each session, the FSFI validated in Turkish, the Female Genital Self-Image Scale (FGSIS), the Female Sexual Distress Scale-Revised (FSDS-R), and Rosenberg's Self-Esteem Scale were used and in the final follow-up, and the Patient Global Impression of Improvement (PGI-I) was performed and the results were analyzed.

Results: Following the application of the PRP, the total FSFI score was observed as 27.88±4.80 and the total score was 26 and above in 50% of the patients (p<0.001). Orgasm subdomain scores were found as 2.11±1.20 before the PRP treatment and 4.48±1.14 afterwards (p<0.001). A significant change was observed in all sub-domains after PRP and it was observed that this change started after the first administration (p<0.001). A statistically significant increase was determined in FGSIS genital perception scores, which was significant between the 1st and 2nd months (p<0.001). The FSDS-R scores showed a minimal increase in stress scores as the application number increased, but a statistically significant decrease was observed in the 4th administration (p<0.001). No statistically significant difference was found in Rosenberg Scale scores before and after treatment (p=0.389). High satisfaction was found in PGI-I scores.

Conclusion: As a minimally invasive method, PRP administration to the distal anterior vaginal wall may improve female sexuality with high satisfaction.

Keywords: Platelet-rich plasma; female orgasmic disorder; female sexual dysfunction.

Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

©Copyright 2019 by Turkish Society of Obstetrics and Gynecology | Turkish Journal of Obstetrics and Gynecology published by Galenos Publishing House.

Figures

Figure 1
Figure 1
The application areas to the lower anterior vaginal wall and around the clitoris.
Figure 2
Figure 2
Graphs of Mean Female Sexual Function Index Total score at application times. Bars are standard deviation. After PRP; 6th month checks are shown. FSFI: Female Sexual Function index, PRP: Platelet-rich plasma
Figure 3
Figure 3
Graphs of mean Female Sexual Function Index (FSFI) subdomain scores at application times Mean FSFI desire score, B. Mean FSFI arousal score, C. Mean FSFI lubrication score, D. Mean FSFI orgasm score, E. Mean FSFI satisfaction score, F. Mean FSFI pain score. Bars are standard deviation. After PRP; 6th month checks are shown.
Figure 4
Figure 4
Graphs of mean the Female Genital Self-Image Scale Total score at application times. Bars are standard deviation. After platelet-rich plasma; 6th month checks are shown.
Figure 5
Figure 5
Graphs of Mean the Female Sexual Distress scale-revised Total score at application times. Bars are standard deviation. After PRP; 6th month checks are shown. PRP: Platelet-rich plasma

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