Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation
N S Majhail, J D Rizzo, S J Lee, M Aljurf, Y Atsuta, C Bonfim, L J Burns, N Chaudhri, S Davies, S Okamoto, A Seber, G Socie, J Szer, M T Van Lint, J R Wingard, A Tichelli, Center for International Blood and Marrow Transplant Research, American Society for Blood and Marrow Transplantation, European Group for Blood and Marrow Transplantation, Asia-Pacific Blood and Marrow Transplantation Group, Bone Marrow Transplant Society of Australia and New Zealand, East Mediterranean Blood and Marrow Transplantation Group, Sociedade Brasileira de Transplante de Medula Ossea, N S Majhail, J D Rizzo, S J Lee, M Aljurf, Y Atsuta, C Bonfim, L J Burns, N Chaudhri, S Davies, S Okamoto, A Seber, G Socie, J Szer, M T Van Lint, J R Wingard, A Tichelli, Center for International Blood and Marrow Transplant Research, American Society for Blood and Marrow Transplantation, European Group for Blood and Marrow Transplantation, Asia-Pacific Blood and Marrow Transplantation Group, Bone Marrow Transplant Society of Australia and New Zealand, East Mediterranean Blood and Marrow Transplantation Group, Sociedade Brasileira de Transplante de Medula Ossea
Abstract
Advances in hematopoietic cell transplantation (HCT) technology and supportive care techniques have led to improvements in long-term survival after HCT. Emerging indications for transplantation, introduction of newer graft sources (for example, umbilical cord blood) and transplantation of older patients using less intense conditioning regimens have also contributed to an increase in the number of HCT survivors. These survivors are at risk for developing late complications secondary to pre-, peri- and post-transplant exposures and risk factors. Guidelines for screening and preventive practices for HCT survivors were published in 2006. An international group of transplant experts was convened in 2011 to review contemporary literature and update the recommendations while considering the changing practice of transplantation and international applicability of these guidelines. This report provides the updated recommendations for screening and preventive practices for pediatric and adult survivors of autologous and allogeneic HCT.
Source: PubMed