Promising Option for Treatment of Striae Alba: Fractionated Microneedle Radiofrequency in Combination with Fractional Carbon Dioxide Laser

Farahnaz Fatemi Naeini, Shadi Behfar, Bahareh Abtahi-Naeini, Shima Keyvan, Mohsen Pourazizi, Farahnaz Fatemi Naeini, Shadi Behfar, Bahareh Abtahi-Naeini, Shima Keyvan, Mohsen Pourazizi

Abstract

Background. A consistent treatment has not been proposed for treatment of Striae Alba (SA). The present study was designed to compare the fractionated microneedle radiofrequency (FMR) alone and in combination with fractional carbon dioxide laser (FMR + CO2) in the treatment of SA. Methods. Forty-eight pairs of SA from six patients were selected. Right or left SAs were randomly assigned to one of the treatment groups. The surface area of the SA before and after treatment and clinical improvement using a four-point scale were measured at the baseline, after one and three months. Results. The mean age of the patients was 30.17 ± 5.19 years. The mean difference of the surface area between pre- and posttreatment in the FMR + CO2 group was significantly higher than that in the FMR group (p = 0.003). Clinical improvement scales showed significantly higher improvement in the FMR + CO2 group than in the FMR group in the first and second follow-up (p = 0.002 and 0.004, resp.). There were no major persistence side-effects in both groups. Conclusions. The results showed that FMR + CO2 laser was more effective than FMR alone in the treatment of SA.

Figures

Figure 1
Figure 1
CONSORT flow chart of the study.
Figure 2
Figure 2
Striae alba on the right calve one month after the end of study. The purple areas denote the measured area by PictZar Digital Planimetry Software.
Figure 3
Figure 3
The measured SA area at baseline, after treatment and in the follow-up in FMR and FMR + CO2 group.
Figure 4
Figure 4
Striae distensae on the buttock of a 30-year-old patient. Significant improvement at 3 months after the end of the study: (a) at baseline; (b) after one month; (c) after three months.
Figure 5
Figure 5
Improvement in clinical appearance of striae alba. Baseline (a) and posttreatment (b) with fractionated microneedle radiofrequency combined with fractional carbon dioxide laser.
Figure 6
Figure 6
Immediate erythema at the site of treatment in a patient in FMR + CO2 group.

References

    1. Zheng P., Lavker R. M., Kligman A. M. Anatomy of striae. British Journal of Dermatology. 1985;112(2):185–193. doi: 10.1111/j.1365-2133.1985.tb00082.x.
    1. McDaniel D. H. Laser therapy of stretch marks. Dermatologic Clinics. 2002;20(1):67–76. doi: 10.1016/S0733-8635(03)00046-9.
    1. Elsaie M. L., Baumann L. S., Elsaaiee L. T. Striae distensae (stretch Marks) and different modalities of therapy: an update. Dermatologic Surgery. 2009;35(4):563–573. doi: 10.1111/j.1524-4725.2009.01094.x.
    1. De Angelis F., Kolesnikova L., Renato F., Liguori G. Fractional nonablative 1540-nm laser treatment of striae distensae in Fitzpatrick skin types II to IV: clinical and histological results. Aesthetic Surgery Journal. 2011;31(4):411–419. doi: 10.1177/1090820x11402493.
    1. Burrows N., Lovell C. Rook's Textbook of Dermatology. 7th. 2004. Disorders of connective tissue; pp. 2241–2312.
    1. Atwal G. S. S., Manku L. K., Griffiths C. E. M., Polson D. W. Striae gravidarum in primiparae. British Journal of Dermatology. 2006;155(5):965–969. doi: 10.1111/j.1365-2133.2006.07427.x.
    1. Alexiades-Armenakas M., Sarnoff D., Gotkin R., Sadick N. Multi-center clinical study and review of fractional ablative CO2 laser resurfacing for the treatment of rhytides, photoaging, scars and striae. Journal of Drugs in Dermatology. 2011;10(4):352–362.
    1. Bak H., Kim B. J., Lee W. J., et al. Treatment of striae distensae with fractional photothermolysis. Dermatologic Surgery. 2009;35(8):1215–1220. doi: 10.1111/j.1524-4725.2009.01221.x.
    1. Naeini F. F., Nikyar Z., Mokhtari F., Bahrami A. Comparison of the fractional CO2 laser and the combined use of a pulsed dye laser with fractional CO2 laser in striae alba treatment. Advanced Biomedical Research. 2014;3, article 184 doi: 10.4103/2277-9175.140090.
    1. Kim B. J., Lee D. H., Kim M. N., et al. Fractional photothermolysis for the treatment of striae distensae in Asian skin. American Journal of Clinical Dermatology. 2008;9(1):33–37. doi: 10.2165/00128071-200809010-00003.
    1. Fatemi Naeini F., Abtahi-Naeini B., Pourazizi M., Nilforoushzadeh M. A., Mirmohammadkhani M. Fractionated microneedle radiofrequency for treatment of primary axillary hyperhidrosis: a sham control study. Australasian Journal of Dermatology. 2015;56(4):279–284. doi: 10.1111/ajd.12260.
    1. Lee S. E., Kim J. H., Lee S. J., et al. Treatment of striae distensae using an ablative 10,600-nm carbon dioxide fractional laser: a retrospective review of 27 participants. Dermatologic Surgery. 2010;36(11):1683–1690. doi: 10.1111/j.1524-4725.2010.01719.x.
    1. Fatemi Naeini F., Pourazizi M., Abtahi-Naeini B., Nilforoushzadeh M. A., Najafian J. A novel option for treatment of primary axillary hyperhidrosis: fractionated microneedle radiofrequency. Journal of Postgraduate Medicine. 2015;61(2):141–143. doi: 10.4103/0022-3859.153111.
    1. Yang Y. J., Lee G.-Y. Treatment of striae distensae with nonablative fractional laser versus ablative CO2 fractional laser: a randomized controlled trial. Annals of Dermatology. 2011;23(4):481–489. doi: 10.5021/ad.2011.23.4.481.
    1. Abtahi-Naeini B., Naeini F. F., Adibi N., Pourazizi M. Quality of life in patients with primary axillary hyperhidrosis before and after treatment with fractionated microneedle radiofrequency. Journal of Research in Medical Sciences. 2015;20(7):631–635.
    1. Naeini F. F., Saffaei A., Pourazizi M., Abtahi-Naeini B. Histopathological evidence of efficacy of microneedle radiofrequency for treatment of axillary hyperhidrosis. Indian Journal of Dermatology, Venereology and Leprology. 2015;81(3):288–290. doi: 10.4103/0378-6323.154789.
    1. Ryu H.-W., Kim S.-A., Jung H. R., Ryoo Y.-W., Lee K.-S., Cho J.-W. Clinical improvement of striae distensae in korean patients using a combination of fractionated microneedle radiofrequency and fractional carbon dioxide laser. Dermatologic Surgery. 2013;39(10):1452–1458. doi: 10.1111/dsu.12268.
    1. Seo K. Y., Yoon M. S., Kim D. H., Lee H. J. Skin rejuvenation by microneedle fractional radiofrequency treatment in Asian skin; clinical and histological analysis. Lasers in Surgery and Medicine. 2012;44(8):631–636. doi: 10.1002/lsm.22071.
    1. Park K. Y., Kim H. K., Kim S. E., Kim B. J., Kim M. N. Treatment of striae distensae using needling therapy: a pilot study. Dermatologic Surgery. 2012;38(11):1823–1828. doi: 10.1111/j.1524-4725.2012.02552.x.
    1. Cho S. I., Chung B. Y., Choi M. G., et al. Evaluation of the clinical efficacy of fractional radiofrequency microneedle treatment in acne scars and large facial pores. Dermatologic Surgery. 2012;38(7):1017–1024. doi: 10.1111/j.1524-4725.2012.02402.x.
    1. Gould D., Kelly D., Goldstone L., Gammon J. Examining the validity of pressure ulcer risk assessment scales: developing and using illustrated patient simulations to collect the data. Journal of Clinical Nursing. 2001;10(5):697–706. doi: 10.1046/j.1365-2702.2001.00525.x.
    1. Elson M. L. Treatment of striae distensae with topical tretinoin. Journal of Dermatologic Surgery and Oncology. 1990;16(3):267–270. doi: 10.1111/j.1524-4725.1990.tb03962.x.
    1. Jiménez G. P., Flores F., Berman B., Gunja-Smith Z. Treatment of striae rubra and striae alba with the 585-nm pulsed-dye laser. Dermatologic Surgery. 2003;29(4):362–365. doi: 10.1046/j.1524-4725.2003.29086.x.
    1. Longo L., Postiglione M. G., Marangoni O., Melato M. Two-year follow-up results of copper bromide laser treatment of striae. Journal of Clinical Laser Medicine and Surgery. 2003;21(3):157–160. doi: 10.1089/104454703321895617.
    1. Goldberg D. J., Sarradet D., Hussain M., Alam M. 308-nm excimer laser treatment of mature hypopigmented striae. Dermatologic Surgery. 2003;29(6):596–599. doi: 10.1046/j.1524-4725.2003.29144.x.
    1. Shokeir H., El Bedewi A., Sayed S., El Khalafawy G. Efficacy of pulsed dye laser versus intense pulsed light in the treatment of striae distensae. Dermatologic Surgery. 2014;40(6):632–640. doi: 10.1111/dsu.0000000000000007.
    1. Hernández-Pérez E., Colombo-Charrier E., Valencia-Ibiett E. Intense pulsed light in the treatment of striae distensae. Dermatologic Surgery. 2002;28(12):1124–1130. doi: 10.1046/j.1524-4725.2002.02111.x.
    1. Goldman A., Rossato F., Prati C. Stretch marks: treatment using the 1,064-nm Nd:YAG laser. Dermatologic Surgery. 2008;34(5):686–692. doi: 10.1111/j.1524-4725.2008.34129.x.
    1. Petro I. Fractional photothermolysis tackles striae distensae. Dermatology Times. 2007;28:94–96.
    1. Alster T. S., Tanzi E. L., Lazarus M. The use of fractional laser photothermolysis for the treatment of atrophic scars. Dermatologic Surgery. 2007;33(3):295–299. doi: 10.1111/j.1524-4725.2007.33059.x.
    1. Naeini F. F., Soghrati M. Fractional CO2 laser as an effective modality in treatment of striae alba in skin types III and IV. Journal of Research in Medical Sciences. 2012;17(10):928–933.

Source: PubMed

3
Subscribe