Elevation of plasma angiotensin II level is a potential pathogenesis for the critically ill COVID-19 patients
Zhiyong Wu, Rui Hu, Cuizhen Zhang, Wei Ren, Anfeng Yu, Xiaoyang Zhou, Zhiyong Wu, Rui Hu, Cuizhen Zhang, Wei Ren, Anfeng Yu, Xiaoyang Zhou
No abstract availableKeywords: ACE2; Angiotensin II; COVID-19; SARS-CoV-2.
Conflict of interest statement
The authors declare that they have no competing interests.
Figures
The positive rate and concentration of plasma renin and Ang II in different groups. a There were no statistical differences in the concentration of renin in patients with different severity of COVID-19. b The plasma Ang II concentration in the critically ill COVID-19 cases and severe COVID-19 cases was significantly higher than that of the mild COVID-19 cases. c, d The renin and Ang II positive rate in the three groups showed no statistical difference. e There was no statistical difference in the concentration of renin in patients with critically ill COVID-19 compared with the control. f The plasma Ang II concentration in the critically ill COVID-19 cases was significantly higher than that of control. g The renin positive rate in the two groups showed no statistical difference. h The plasma Ang II positive rate in the critically ill COVID-19 cases was significantly higher than that of control. Control: critically ill non-COVID-19 cases. *P < 0.05, **P < 0.01
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Source: PubMed