Influence of oxygen on wound healing

Wai Lam Yip, Wai Lam Yip

Abstract

Oxygen has an important role in normal wound healing. This article reviews the evidence concerning the role of oxygen in wound healing and its influence on the different stages of wound healing. The evidence reviewed has demonstrated that improving oxygenation may be helpful in limiting wound infection, although there is a lack of good quality studies on the role of oxygen in the proliferative phase and in reepithelialisation. Overall, the relationship between oxygen and wound healing is complex. Knowledge of this aspect is important as many treatment modalities for refractory wounds are based on these principles.

Keywords: Inflammatory phase; Oxygen; Proliferative phase; Reepithelialisation; Wound healing.

© 2014 The Author. International Wound Journal © 2014 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Source: PubMed

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