Procalcitonin: Where Are We Now?

Bachar Hamade, David T Huang, Bachar Hamade, David T Huang

Abstract

Procalcitonin is a biomarker that is generally elevated in bacterial infections. This review describes a conceptual framework for biomarkers using lessons from the history of troponin, applies this framework to procalcitonin with a review of observational studies and randomized trials in and out of the intensive care unit, and concludes with clinical recommendations and thoughts on how to test a test.

Keywords: Antibiotics; Mortality; Procalcitonin; Respiratory tract infection; Sepsis.

Copyright © 2019 Elsevier Inc. All rights reserved.

Source: PubMed

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