Clinical Trials on 1- Primary (Sarcomeric) Hypertrophic Cardiomyopathy

Total 1021 results

Universitaire Ziekenhuizen KU Leuven

Completed

Pulse Wave Analysis and Velocity in Patients With Chronic Renal Failure: a Cross-sectional Observational Study to Assess Association With Left Ventricular Hypertrophy, Uremic Toxins and Inflammation.

Left Ventricular Hypertrophy | Arterial Stiffness | CHRONIC RENAL FAILURE

Belgium
Unity Health Toronto
Heart and Stroke Foundation of Canada

Completed

In-Centre Nocturnal Hemodialysis (INHD): A Long-Term Follow-Up Study (INHD)

End-stage Renal Disease | Left Ventricular Hypertrophy

Canada
University of Alberta
Massachusetts General Hospital

Terminated

Risk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis Patients

End Stage Renal Disease

United States, Canada
University Hospitals Cleveland Medical Center
Sanofi

Completed

Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)

Erectile Dysfunction | BPH

United States
Seoul National University Hospital

Unknown

Low Energy HoLEP on IPSS

Quality of Life | Surgery | Complication of Surgical Procedure | Bladder Outlet Obstruction | Prostatic Hypertrophy | Prostate Hyperplasia
Melbourne Health

Completed

Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan

Renal Failure | Left Ventricular Hypertrophy

Australia
Intermountain Health Care, Inc.
NuView Diagnostics

Unknown

Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones. (VPAC)

Prostate Cancer | Kidney Stones | Benign Prostatic Hypertrophy | Bladder Stones

United States
Dr Manvir Kaur Hayer
British Heart Foundation

Unknown

Left Ventricular Fibrosis in Chronic Kidney Disease (FibroCKD)

Myocardial Fibrosis | Chronic Kidney Diseases | Cardio-Renal Syndrome | Uraemic Cardiomyopathy

United Kingdom
Royal Marsden NHS Foundation Trust
King's College London; University College, London; Institute of Cancer Research... and other collaborators

Recruiting

A Study Comparing Urolift and TURP Ahead of Radiotherapy in Men With Urinary Symptoms Secondary to Prostate Enlargement (CO-STAR)

Prostate Cancer

United Kingdom
Sanofi

Completed

Multicenter Prospective Study on the Changes of Sexual Function Following Treatment With Alfuzosin (Xatral XL®) in Patients With Benign Prostate Hypertrophy

BPH/LUTS/Sexual Functions

Korea, Republic of
M.D. Anderson Cancer Center
Incyte Corporation

Not yet recruiting

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

Myelofibrosis | Splenomegaly

United States
Ann & Robert H Lurie Children's Hospital of Chicago
Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases...

Completed

Proteomics of Primary Hyperoxaluria Type 1 (PH1)

Primary Hyperoxaluria Type 1
Mansoura University

Completed

Holmium Laser Versus Thulium Laser Versus Bipolar Enucleation of the Prostate.

Prostate Hypertrophy | Holmium Laser | Thulium Laser | Bipolar Diathermy | Prostate Enucleation

Egypt
Omnia Mohammed Hashem

Suspended

Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Patient

Anemia of Chronic Kidney Disease | Endothelial Dysfunction | Left Ventricular Hypertrophy | Fibroblast Growth Factor 23

Egypt
Isfahan University of Medical Sciences

Completed

Association of Mean Platelet Volume and Cardiovascular Disease in Children With End Stage Renal Disease.

Cardiovascular Diseases | End Stage Renal Disease | Hemodialysis Complication | Children | Left Ventricular Hypertrophy | Peritoneal Dialysis Complication | Mean Platelet Volume | Carotid Intimal Media Thickness
Per Ivarsen

Terminated

Active Vitamin D Effect on Left Ventricular Hypertrophy

Chronic Kidney Disease | Secondary Hyperparathyroidism | Left Ventricular Hypertrophy

Denmark
Batman Training and Research Hospital
Baskent University

Completed

The Effect of Healthy Eating Index on Maternal Thyroid Volume in Hyperemesis Gravidarum

Healthy Diet | Pregnancy Emesis | Thyroid Hypertrophy

Turkey
Rambam Health Care Campus
Technion, Israel Institute of Technology

Unknown

The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin (RING UB LIGASE)

Group 1: Trauma Operation for Otherwise Healthy Patients | Group 2: Primary Tumors of Mesenchymal Origin

Israel
St George's, University of London
Guy's and St Thomas' NHS Foundation Trust

Unknown

Vitamin D Supplementation and Cardiac Hypertrophy in Chronic Kidney Disease (CKD) (5C)

Chronic Kidney Disease

United Kingdom
Beth Israel Deaconess Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia | Urinary Obstruction | Prostate Disease | Prostate Hyperplasia | Prostate Hypertrophy | Prostate Pain | Urinary Tract Disease

United States
Dicerna Pharmaceuticals, Inc.

Terminated

A Study of DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)

Primary Hyperoxaluria Type 1

Netherlands, Germany
Northwestern University

Active, not recruiting

Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

Urologic Diseases | Kidney Calculi | Benign Prostatic Hypertrophy

United States
Mayo Clinic

Completed

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) (Aim 3)

Renal Impairment | Cardiomyopathy

United States
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Doravirine (MK-1439) in Participants With Human Immunodeficiency Virus 1 (HIV-1) (MK-1439-018) (DRIVE-FORWARD)

HIV-1
University Hospital, Bordeaux

Completed

A-botulinic Toxin for Symptomatic Benign Prostate Hypertrophy (PROTOX)

Prostatic Hyperplasia

France
University Hospital Birmingham NHS Foundation Trust

Completed

Effects of a Reduction in Renal Function on Cardiovascular Structure and Function (CRIB-DONOR II)

Hypertension | Chronic Kidney Disease | Hypertrophy, Left Ventricular

United Kingdom
Mayo Clinic
Scios, Inc.

Completed

Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure

Kidney Diseases | Congestive Heart Failure | Cardiomyopathy

United States
City of Hope Medical Center

Not yet recruiting

CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS

HIV-1

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy

HIV-1

United States
HeNan Sincere Biotech Co., Ltd

Completed

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Gilead Sciences

Active, not recruiting

Study To Evaluate Emtricitabine/Tenofovir Alafenamide (F/TAF) in Human Immunodeficiency Virus 1 (HIV-1) Infected Children and Adolescents Virologically Suppressed on a 2- Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (2-NRTI)-Containing Regimen

HIV-1

United States, Panama, South Africa
Northwell Health
Icahn School of Medicine at Mount Sinai

Completed

Ventricular Arrhythmias in Uremic Cardiomyopathy

Cardiomyopathy

United States
M.D. Anderson Cancer Center
Onconova Therapeutics, Inc.

Terminated

Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia

Leukemia | Anemia | Myelofibrosis | Splenomegaly

United States
GlaxoSmithKline

Completed

Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan

Prostatic Hyperplasia
Medical University of Vienna
Vienna Dialysis Center

Recruiting

SGLT2 Inhibition in Hemodialysis (DAPA-HD)

Diabetes Mellitus, Type 2 | Hemodialysis | Chronic Kidney Disease | Kidney Failure | Left Ventricular Hypertrophy

Austria
Johns Hopkins Bloomberg School of Public Health
University of California, San Francisco; University of Toronto; National Institute... and other collaborators

Completed

HIV Treatment Retention Interventions for Women Living With HIV (Siyaphambili Study)

HIV-1 Virologic Response

South Africa
Hospices Civils de Lyon

Completed

IDENTIFICATION OF A MULTI-ANALYTE PROFILE FOR PRIMARY HYPEROXALURIA AND COMPARISON WITH HEALTHY SIBLINGS AND IDIOPATHIC HYPERCALCIURIA (PH1)

Idiopathic Hypercalciuria | Primary Hyperoxaluria Type 1

France
VA Office of Research and Development
Merck Sharp & Dohme LLC; Endo Pharmaceuticals

Completed

5-Alpha Reductase and Anabolic Effects of Testosterone

Sarcopenia | Muscle Atrophy | Male Hypogonadism | Benign Prostate Hypertrophy

United States
Mayo Clinic

Completed

Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) (Aim2)

Renal Impairment | Cardiomyopathy

United States
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Recruiting

Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function (PHYOX8)

Primary Hyperoxaluria Type 3 | Primary Hyperoxaluria Type 2 | Primary Hyperoxaluria Type 1 | Primary Hyperoxaluria

United States, Canada, Lebanon, Turkey, United Kingdom, Germany, Italy, Japan, Poland, Spain, United Arab Emirates
University of Maryland, Baltimore
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanisms of Hypoglycemia Associated Autonomic Dysfunction Question 2 (Alp Ex)

Type 1 Diabetes

United States
Merck Sharp & Dohme LLC

Completed

Effects of Switching From ATRIPLA™ (Efavirenz, Tenofovir, Emtricitabine) to MK-1439A (Doravirine, Tenofovir, Lamivudine) in Virologically-Suppressed Participants (MK-1439A-028)

HIV-1 | Central Nervous System
Hope Biosciences Stem Cell Research Foundation
Hope Biosciences

No longer available

"Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis"

Primary Lateral Sclerosis, Adult, 1

United States
Maaynei Hayesha Medical Center

Completed

The Effect of Spermatic Vein Embolization on Prostatic Hypertrophy

Varicocele

Israel
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Obinutuzumab and Lenalidomide in Treating Patients With Previously Untreated Stage II-IV Grade 1-3a Follicular Lymphoma

Fatigue | Weight Loss | Fever | Splenomegaly | Ann Arbor Stage II Grade 1 Follicular Lymphoma | Ann Arbor Stage II Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1... and other conditions

United States
Jennifer Cowger , MD, MS
POM Wonderful LLC

Terminated

The Impact of Pomegranate Extract on Chronic Cardiomyopathy Complicated by Renal Insufficiency (ImPrOVE): a Pilot Study (ImPrOVE)

Heart Failure | Cardiomyopathy

United States
Abbott
Massachusetts General Hospital; Harvard University

Terminated

The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5 (PRIMO II)

Hypertrophy, Left Ventricular | Chronic Kidney Disease (CKD) Stage 5

Italy, United States, Taiwan, Poland, United Kingdom, Greece, Germany, Russian Federation, Spain, Australia, Czech Republic, Puerto Rico, Romania
Merck Sharp & Dohme LLC

Withdrawn

MK-8510 Monotherapy for the Treatment of Anti-retroviral naïve Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8510-002)

HIV-1 | Immunodeficiency Virus Type 1, Human | Human Immunodeficiency Virus Type 1 | Human Immunodeficiency Virus 1
Samsung Medical Center
GlaxoSmithKline

Completed

Effect of Dutasteride on Bladder Wall Hypertrophy in Patients With Benign Prostatic Obstruction

Benign Prostatic Hyperplasia

Korea, Republic of
Janssen Sciences Ireland UC

Completed

A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years

HIV-1

United States, South Africa, Ukraine, Kenya, Thailand, India, Romania, Uganda

Clinical Trials on 1- Primary (Sarcomeric) Hypertrophic Cardiomyopathy

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