Clinical Trials on Abnormality

Total 288 results

Celgene

Completed

Lenalidomide Safety/Efficacy in Myelodysplastic Syndromes (MDS) Associated With a Deletion (Del)(5q) Cytogenetic Abnormality

Myelodysplastic Syndromes

United States, Germany
Tel-Aviv Sourasky Medical Center

Unknown

Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study. (ZYCTFEA)

Bone Metastases | Orthopedic Disorder | Bone Neoplasm of Hip (Diagnosis) | Proximal Femoral Metaphyseal Abnormality
Massimo Raimondo, M.D.
Digestive Care, Inc.

Terminated

PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Insufficiency | Pancreatic Enzyme Abnormality

United States
Universitair Ziekenhuis Brussel

Recruiting

The Role of Natural Killer, Complement and T-lymphocytes in COVID-19 Disease, a Prospective Monocentric Study (TONIC)

Covid19 | Peripheral Blood Mononuclear Cells | Complement Abnormality

Belgium
Children's Hospital Los Angeles
University of Pittsburgh; Arizona State University

Recruiting

Childhood Outcomes of Preterm Brain Abnormalities

Premature Birth | Neurodevelopmental Disorders | Brain Lesion | Brain Development Abnormality

United States
National University of Malaysia

Unknown

Endometrial Heparin-binding Epidermal Growth Factor Expression

Gene Abnormality

Malaysia
Assistance Publique - Hôpitaux de Paris

Completed

Corpus Callosum Agenesis and Intellectual Disability (ACCREM)

Intellectual Deficiency | Cerebral Abnormality

France
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); Medical College of Wisconsin and other collaborators

Completed

Fetal and Neonatal Magnetophysiology

Long QT Syndrome | Fetal Arrhythmia | Abnormality in Fetal Heart Rate or Rhythm

United States
Fundación Centro Nacional de Investigaciones Cardiovasculares...
Hospital Clinic of Barcelona; Fundació Institut de Recerca de l'Hospital de... and other collaborators

Unknown

Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure (SPHERE-HF)

Heart Failure | Pulmonary Hypertension | Mirabegron | Pulmonary Vascular Resistance Abnormality
Karolinska Institutet
Karolinska University Hospital

Enrolling by invitation

Structural Chromosome Rearrangements and Brain Disorders

Rare Diseases | Genetic Disease | Chromosome Abnormality

Sweden
Westat
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

International Cohort Study of Children Born to Women Infected With Zika Virus During Pregnancy

Eye Abnormalities | Hearing Loss | Zika | Neurodevelopmental Abnormality | Growth Delay

Brazil, Colombia, Peru, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects

Gonococcal Infection | Electrocardiogram Repolarisation Abnormality

United States
Ministry of Health, Saudi Arabia

Not yet recruiting

Measurment of Interleuukin-6 at Exhaled Breath Condensate of Covid-19 Patients and Post Covid-19 Patients With Lung Fibrosis Randomized Controlled Study

COVID-19 | Inflammatory Response | Immunological Abnormality
Indonesia University

Completed

The Role of Probiotics in HIV Patients With Immunological Non-Responder (PIONIR)

HIV Infections | Immunological Abnormality

Indonesia
National Eye Institute (NEI)

Completed

Abnormalities of the Eye's Anterior Chamber, Iris, Cornea and Lens

Ocular Hypertension | Open Angle Glaucoma | Aniridia | Eye Abnormality

United States
Centre Hospitalier Universitaire, Amiens
Centre Henri Becquerel; Hôpital Jeanne de Flandre LIlle

Recruiting

Evaluation of Optical Genome Mapping in Phi Negative Myeloproliferative Neoplasia in the Detection of Acquired Cytogenetic Abnormalities (MYELOCARTOCH)

Myeloproliferative Neoplasm | Optical Genome Mapping | Cytogenetics | Clonality | Prognostic Stratification

France
Changhai Hospital

Unknown

Application of UCAD for Diagnosing Urothelial Carcinoma.

Diagnoses Disease | Urothelial Carcinoma | Chromosomal Abnormality | Urine Marking

China
University Hospital Hradec Kralove
American Association for Thoracic Surgery

Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis (AOSIS)

Infections | Systemic Inflammatory Response Syndrome | Immunological Abnormality | Aortic Diseases | Thoracic Aortic Aneurysm

Czechia
Firat University
Pamukkale University

Unknown

To Investigate the Effect of Aerobic Exercise on Neurophysiological Values and Functionality in Individuals With Multiple Sclerosis.

Multiple Sclerosis, Relapsing-Remitting | Aerobic Exercise | FNDC5 | Irisin Hormone | EMG: Axonal Abnormality
Royal Centre for Defence Medicine
University of Oxford

Completed

Iron Status and Cardiopulmonary Physiology

Iron-deficiency | Pulmonary Vascular Resistance Abnormality | Ventricular Function | Altitude Hypoxia
University Hospital Southampton NHS Foundation...

Recruiting

DNA Repair in Patients With Stable Angina. (DECODE II)

Coronary Artery Disease | Coronary Arteriosclerosis | DNA Damage | DNA Repair Abnormality

United Kingdom
Taipei Medical University

Enrolling by invitation

The Effect of Computerized Vestibular Function Assessment and Training System Combined With Cognitive/Motor Dual-task

Dizziness | Cognitive Decline | Vestibular Abnormality | Vestibular Function Disorder

Taiwan
Hellenic Cooperative Oncology Group

Completed

Germline Mutations in Pancreatic Adenocarcinoma (PaMPA)

Pancreatic Cancer | Hereditary Cancer | Predisposition, Genetic | Germline Mutation Abnormality

Greece
National Taiwan University Hospital

Unknown

Genotyping of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Gene Abnormality

Taiwan
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); The University of New South... and other collaborators

Completed

Pravastatin for Hyperlipidaemia in HIV.

HIV Infections | Cardiovascular Disease | Lipodystrophy | Glucose Metabolism | Lipid Metabolism | Metabolic Abnormality

Australia
Connecticut Children's Medical Center

Completed

Furosemide Use to Fill the Bladder of Pediatric Females Awaiting Pelvic Ultrasound

Ovarian Torsion

United States
Germans Trias i Pujol Hospital

Withdrawn

Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis (INPSYDER)

Psoriasis | Major Depressive Disorder | Neuroinflammation | Cognitive Symptom | Immunological Abnormality

Spain
Hospital de Mataró

Completed

Sensory Neuromodulation Protocol for the Treatment of Post-stroke Oropharyngeal Dysphagia. (FIS2014)

Stroke | Dysphagia | Swallowing Disorder | Neurophysiologic Abnormality
Region Skane

Recruiting

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

C3 Glomerulopathy | C3 Glomerulonephritis | Dense Deposit Disease | Membranoproliferative Glomerulonephritis | Complement Abnormality

Sweden
Leiden University Medical Center
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research

Unknown

Neurodevelopmental Outcome After Fetal Neonatal AlloImmune Thrombocytopenia (NOFNAIT)

Neurodevelopmental Abnormality | Fetal and Neonatal Alloimmune Thrombocytopenia | Long Term Adverse Effects | Intravenous Immunoglobulin Adverse Reaction

Netherlands
Andrea Rossetti, MD

Completed

Continuous EEG Randomized Trial in Adults (CERTA)

Coma | Outcome, Fatal | EEG With Abnormally Slow Frequencies | EEG With Periodic Abnormalities

Switzerland
Hospices Civils de Lyon

Recruiting

Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma (SCITH-MESO)

Mesothelioma, Malignant | Pleural Mesothelioma | Gene Abnormality

France
Central Hospital, Nancy, France

Terminated

Contribution of Contrast Enhanced Ultrasound in the Diagnosis of Adnexal Torsion (AGATA)

Adnexal Torsion

France
Nantes University Hospital

Active, not recruiting

Neuropsychological Development and Executive Functioning of Children Born to HIV- Infected Mothers ( NEUROPSY-HEU ) (NEUROPSY-HEU)

HIV Infections | Executive Dysfunction | Neurophysiologic Abnormality | Exposure During Pregnancy

France
Gillette Children's Specialty Healthcare
Lite Run Inc.

Completed

Post-operative Lite Run Study

Cerebral Palsy | Neurologic Disorder | Spina Bifida | Chromosome Abnormality

United States
Hôpital Louis Mourier

Completed

Microbial and Pharmacological Assessment of Chlorhexidine

Pneumonia, Ventilator-Associated | Infection, Bacterial | Chlorhexidine | Oropharynx Abnormality | Bacterium; Agent
Afyon Kocatepe University Hospital

Completed

The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes

Retinal Degeneration | Diabetic Retinopathy | Macula Abnormality | Laser Burn of Retina
Montreal Heart Institute
Masimo Corporation

Completed

Cerebral Monitoring and Post-operative Delirium and Outcomes (Techno-5)

Delirium | Cerebral Desaturation | EEG With Abnormally Slow Frequencies

Canada
IRCCS Burlo Garofolo

Recruiting

Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion

Adnexal Torsion

Austria, Italy, Serbia
Sheba Medical Center

Recruiting

Ovarian Reserve After Ovarian Torsion (OTAMH)

Ovarian Torsion

Israel
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Precision Medicine for Patients With Identified Actionable Mutations

Lymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation Abnormality

United States
Thomas Jefferson University
Jawaharlal Nehru Medical College; S. Nijalingappa Medical College; Raichur Institute...

Active, not recruiting

RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study (RAPIDIRON-KIDS)

Autism Spectrum Disorder | Iron Deficiency Anemia | Neurodevelopmental Abnormality

India
Department of Neurorehabilitation, Hospital of...
I.R.C.C.S. Fondazione Santa Lucia

Completed

Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients (PL-PC19)

COVID-19 | Fatigue | Cognitive Deficit | Neurophysiologic Abnormality

Italy
University of Texas at Austin

Not yet recruiting

Clinical Validation of zEEG, a Wireless EEG Recording System for Pediatric and Adult Patients With Epilepsy

Epilepsy | EEG With Abnormally Slow Frequencies | EEG; Paroxysms, Occipital, Epilepsy of Childhood | EEG With Periodic Abnormalities | EEG; Spikes, Centrotemporal, Epilepsy of Childhood

United States
University of North Carolina, Chapel Hill
National Human Genome Research Institute (NHGRI); East Carolina University; Mission...

Active, not recruiting

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 (NCGENES2)

Neuromuscular Diseases | Movement Disorders | Intellectual Disability | Autism Spectrum Disorder | Microcephaly | Hearing Loss | Genetic Disease | Inborn Errors of Metabolism | Epilepsy; Seizure | Brain Malformation | Hypotonia | Development Delay | Chromosome Abnormality | Dysmorphic Features | Skeletal Dysplasia | Congenital... and other conditions

United States
Technical University of Munich

Completed

Reduction of Intraoperative EEG Burst Suppression (BsR)

Postoperative Delirium | Burst Suppression | EEG With Abnormally Slow Frequencies

Germany
Zetagen Therapeutics, Inc

Not yet recruiting

Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease

Disc Degeneration | Myelopathy Cervical | Disc Disease | Radiculopathy, Cervical | Neurological Abnormality
Instituto do Cancer do Estado de São Paulo
Servier

Recruiting

Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil (BRALLA)

Acute Lymphoid Leukemia | Chemotherapeutic Toxicity | Minimal Residual Disease | Gene Abnormality

Brazil
Brigham and Women's Hospital

Recruiting

Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development

Preterm Birth | Neurodevelopmental Disorders | Breast Milk Expression | Nutrition Disorder, Infant | Brain Development Abnormality

United States
Johns Hopkins University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

The Use of Eculizumab in HELLP Syndrome

Morbidity;Newborn | Preeclampsia Severe | Complement Abnormality | HELLP Syndrome (HELLP), Third Trimester | Maternal Injury

United States

Clinical Trials on Abnormality

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations