Clinical Trials on Access and Evaluation in South Africa

Total 19452 results

PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
RTI International
Medical Research Council, South Africa

Completed

Cape Town Young Women's Health CoOp

Human Immunodeficiency Virus (HIV) | Condomless Sex | Alcohol and Drug Use | Sexually Transmitted Infections (STIs) | Violence and Victimization | Access and Linkage to Healthcare | Education Advancement

South Africa
Mindset Medical

Completed

A Multi-Center Prospective Open Label Study of a Web-based Application for Pulse Rate in Adult Patients

Vital Sign Evaluation

United States
Vidacare Corporation

Terminated

Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route

Intraosseous Vascular Access Patients Requiring CT Exam

United States
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
SurModics, Inc.

Active, not recruiting

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon (AVess FIH)

Hemodialysis Access Failure

Australia, New Zealand
Novartis Pharmaceuticals

Terminated

Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS

Cryptococcal Meningitis

South Africa
Boston University
World Bank (Lead institution); Republic of South Africa National Department...

Completed

Evaluation of South Africa's National Adherence Strategy (ENHANCE)

Hypertension | Diabetes | HIV | Tuberculosis

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Janssen Cilag N.V./S.A.

Completed

A Follow-Up Study of Schizophrenic Participants Following Treatment Discontinuation After Remission From a First Psychotic Episode

Schizophrenia

South Africa
Swiss Federal Institute of Technology
North-West University, South Africa

Completed

Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women

Obesity

South Africa
Medical College of Wisconsin
National Institute of Mental Health (NIMH)

Completed

Experimental Analysis of HIV Risk Assessment Reactivity in South African Clinics

HIV Prevention and Assessment Reactivity

South Africa
GlaxoSmithKline
Parexel

Completed

Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects

Infections, Bacterial

South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Completed

InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media (InTSHA)

HIV-1-infection | Adolescent Behavior

South Africa
University of Washington
PATH; University of KwaZulu; Umkhuseli Innovation and Research Management (UIRM) and other collaborators

Unknown

Prospective Evaluation of Novel Diagnostics for Tuberculosis in KwaZulu-Natal, South Africa (PROVE-TB)

Tuberculosis

South Africa
Vakzine Projekt Management GmbH
University of Stellenbosch; Farmovs-Parexel Bloemfontein, Republic of South... and other collaborators

Completed

Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison to BCG in Healthy Volunteers in South Africa

Tuberculosis

South Africa
Johns Hopkins University

Completed

Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB

Tuberculosis, Pulmonary

South Africa
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Enrolling by invitation

Transmission of Tuberculosis Among Illicit Drug Use Linkages (TOTAL)

Tuberculosis | Illicit Drug Use

South Africa
Cryonove Pharma
CEISO; Dermatech; Sefako Makgatho Health Sciences University

Completed

Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.

Solar Lentigo | Post-inflammatory Hyperpigmentation | Senile Lentigo

South Africa
GlaxoSmithKline

Completed

Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infants of 7-90 Days Age (Late Onset Disease [LOD])

Streptococcus Agalactiae

South Africa
Smith & Nephew, Inc.

Completed

Treatment of Wounds With a New Adhesive Foam Dressing

Wounds and Injuries | Burns

South Africa
Eli Lilly and Company

Completed

A Study to Compare the Pharmacokinetics and Pharmacodynamics of LY2963016 to Lantus in Healthy Participants

Diabetes Mellitus

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between GSK3542503 Hydrochlorothiazide + Amiloride Hydrochloride 50 mg: 5 mg Tablets and Reference Product in Healthy Adult Participants Under Fasting Conditions

Hypertension

South Africa
ImmunityBio, Inc.

Terminated

THEMBA II T-Cell Vaccine: Vaccination With saRNA COVID-19 Vaccines

COVID-19

South Africa
Boston University
Clinton Health Access Initiative, Nigeria; Health Economics and Epidemiology...

Recruiting

DSD Models at South Africa Sentinel Sites (SENTINEL 2)

HIV

South Africa
Sanofi

Completed

Efficacy and Safety Study of New Ambroxol Hardboiled Lozenges in Acute Pharyngitis (DELICIOUS)

Pharyngitis

South Africa
Gilead Sciences

Active, not recruiting

Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women

HIV-1-infection

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa
Janssen Research & Development, LLC

Completed

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis

Osteoarthritis, Knee

South Africa
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
Johns Hopkins Bloomberg School of Public Health
University of California, San Francisco; University of Toronto; National Institute... and other collaborators

Completed

HIV Treatment Retention Interventions for Women Living With HIV (Siyaphambili Study)

HIV-1 Virologic Response

South Africa
University of Konstanz
University of Stellenbosch; University of Cape Town

Completed

Treatment of Trauma and Violence in the Townships of South Africa

Aggressive Behavior | Post-traumatic Stress Disorder (PTSD)

South Africa
Aeras
Statens Serum Institut

Completed

A Phase I Study to Evaluate Safety and Immunogenicity of AERAS 404 (C-011-404) (C-011-404)

Tuberculosis

South Africa
Drexel University
University of North Carolina, Chapel Hill; University of KwaZulu

Completed

MAMAS: Mentoring Adolescent Mothers at School (MAMAS)

Chlamydia | Gonorrhea | Human Immunodeficiency Virus | Trichomonas Vaginitis | Herpes Simplex Type II

South Africa
Reig Jofre Group

Completed

Bioequivalence Study of Two Inhalation Formulations Containing Budesonide 200 µg

Allergy

South Africa
Aeras
Statens Serum Institut

Completed

Safety and Immunogenicity Study of AERAS-456 Vaccine for Tuberculosis

Latent Tuberculosis | Latent Tuberculosis Bacteriology and Histology Unknown

South Africa
University of Alabama at Birmingham
Merck Sharp & Dohme LLC; University of Washington; Wits Reproductive Health and...

Active, not recruiting

Evaluation of Pharmacokinetic Drug-drug Interactions Between Hormonal Contraceptives and Doravirine-containing ART Among Women Living With HIV in South Africa (EPIC)

HIV Infections | Contraception | Drug-drug Interaction

South Africa
Bukwang Pharmaceutical
Contera Pharma ApS

Completed

Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia (LID)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

South Africa
Massachusetts General Hospital
Boston University; University of Cape Town

Recruiting

South Africa Smoking Cessation and Engagement in HIV/TB Care Care

HIV Infections | Smoking Cessation | Tuberculosis

South Africa
Centers for Disease Control and Prevention
Johns Hopkins University; Sanofi; University of Stellenbosch; University of Cape... and other collaborators

Recruiting

Tuberculosis Clinical Trials Consortium Study 35

Latent Tuberculosis

South Africa
University of Exeter
University College, London; Medical Research Council, South Africa

Completed

Stepping Stones and Creating Futures Plus Pilot

Intimate Partner Violence | Poverty

South Africa
FHI 360
United States Agency for International Development (USAID); University of Witwatersrand...

Completed

Assessing Preference for 3 Female Condoms: A Comparative Evaluation of the PATH Woman's Condom, FC2 and the Reddy 6

Contraception

South Africa
Bavarian Nordic

Completed

Study to Evaluate Safety, Dose Response and Immunogenicity of the Measles Vaccine MVA mBN85B in Healthy Children Aged 6 Months to 6 Years

Measles

South Africa
Centers for Disease Control and Prevention
Yale University; Columbia University; University of KwaZulu

Completed

TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB (LiMiT)

Multi-drug Resistant Tuberculosis | Extensively Drug Resistant Tuberculosis

South Africa
Johns Hopkins University

Completed

Statin Adjunctive Therapy for TB (StAT-TB)

Tuberculosis

South Africa
Cryonove Pharma
Dermatech

Not yet recruiting

Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face (CS5_10)

Lentigo | Solar Lentigo | Post Inflammatory Hyperpigmentation

South Africa
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa

Clinical Trials on Access and Evaluation in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hungary

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations