Clinical Trials on Acidosis, Metabolic in United States

Total 22474 results

UCB Pharma

Completed

A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy

Diabetic Neuropathy

United States
Pfizer

Completed

Study To Evaluate Safety And Tolerability Of Pegaptanib Sodium In Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Anti- VGF Inhibitor

Spain, United Kingdom, Finland, Sweden
Adamas Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Amantadine Hydrochloride (HCl) ER Tablets to Treat Parkinson's Disease Patients With LID. (ALLAY-LID-I)

Parkinson's Disease | Levodopa Induced Dyskinesias (LID)

France, Spain, Germany, Canada, United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Effect Of Pregabalin Treatment In Patients With Diabetic Nerve Pain Who Currently Use A Non-Steroid Anti-Inflammatory Drug (NSAID) For Another Pain

Painful Diabetic Peripheral Neuropathy

United States, Czechia, Sweden, Italy
Osiris Therapeutics

Terminated

Study to Evaluate the Safety and Efficacy of CHAM* for the Treatment of Diabetic Foot Ulcers (*OTI-15-01)

Chronic Diabetic Foot Ulcers

United States
VA Office of Research and Development

Recruiting

Pentoxifylline in Diabetic Kidney Disease (PTXRx)

Diabetic Kidney Disease

United States
Adamas Pharmaceuticals, Inc.

Completed

Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia (EASE LID 3)

Parkinson's Disease (PD) | Dyskinesia | Levodopa-Induced Dyskinesia (LID)

France, Spain, United States, Germany, Austria
AbbVie (prior sponsor, Abbott)

Completed

Safety and Efficacy Study in Subjects With Diabetic Neuropathic Pain

Diabetic Neuropathies | Diabetic Neuropathy, Painful | Diabetic Polyneuropathy | Diabetic Neuralgia | Neuralgia, Diabetic

United States, Canada, France, Germany, Italy, Mexico, Puerto Rico
Abbott Medical Devices

Recruiting

Abbott DBS Post-Market Study of Outcomes for Indications Over Time (ADROIT)

Parkinson Disease | Movement Disorders | Dystonia | Essential Tremor | Tremor | Primary Dystonia | Secondary Dystonia

United States, Australia, Spain, United Kingdom, Finland, France, Germany, Italy, Taiwan
Boehringer Ingelheim

Completed

Profile of Depressive Symptoms in Parkinsons Disease

Depression | Parkinson Disease

Netherlands, Germany, Italy, Switzerland, Austria, France, Spain, United Kingdom
Hoffmann-La Roche

Completed

A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Patients With Spinal Muscular Atrophy (SMA)

Muscular Atrophy, Spinal

Belgium, United Kingdom, Germany, France, Italy, Netherlands, Poland
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS); National Center... and other collaborators

Completed

Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) (ARTFL)

Amyotrophic Lateral Sclerosis (ALS) | Progressive Supranuclear Palsy (PSP) | Corticobasal Degeneration (CBD) | FTLD | Frontotemporal Dementia (FTD) | PPA Syndrome | Behavioral Variant Frontotemporal Dementia (bvFTD) | Semantic Variant Primary Progressive Aphasia (svPPA) | Nonfluent Variant Primary Progressive... and other conditions

United States, Canada
GlaxoSmithKline

Recruiting

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain (NEPTUNE-17)

Pain

United States, Germany, Japan, Spain, Canada, China, United Kingdom, South Africa, Korea, Republic of, France, Poland, Turkey
Prexton Therapeutics

Completed

Study to Evaluate the Efficacy, Safety and Tolerability of PXT002331 (Foliglurax) in Reducing Motor Complications of Levodopa Therapy in Parkinson Disease's Patients (AMBLED)

Parkinson Disease

France, Italy, Spain, Germany, United Kingdom, Austria
Biotec Pharmacon ASA

Completed

Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers

Chronic Diabetic Foot Ulcers

United Kingdom
Pfizer

Completed

Study Evaluating Sumanirole for the Treatment of the Signs and Symptoms of Early Parkinson's Disease

Parkinson Disease

United States, Australia, Spain, Italy, Belgium, Germany, Austria, Peru, Greece, France, Argentina, Puerto Rico, Colombia, Mexico
Quark Pharmaceuticals

Completed

Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients

Optic Atrophy | Non-arteritic Anterior Ischemic Optic Neuropathy

United States, Israel
Chromaderm, Inc.

Completed

Reduction in the Occurrence of Center-Involved Diabetic Macular Edema

Diabetic Retinopathy

United States, Canada, France, Denmark, Australia, Netherlands, Taiwan, Spain, Italy, Germany, Portugal, United Kingdom, Russian Federation, Poland, India, Brazil, Mexico
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Completed

A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).

Painful Diabetic Peripheral Neuropathy

India, Czech Republic, Germany, United Kingdom
GlaxoSmithKline

Completed

Investigational Parkinson's Disease In Patients Not Well Controlled On L-dopa

Parkinson Disease

United States, France, Spain, Poland, Belgium, Hungary, Germany, Italy, Czech Republic
Allergan

Terminated

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Study 04

Diabetes Mellitus | Gastroparesis

United States, Canada, Australia, Thailand, Korea, Republic of, Singapore, Mexico, Belgium, Bulgaria, India, Malaysia, Philippines, Poland, Spain, Ukraine, South Africa, Brazil, Colombia, Austria, Argentina, Germany, Hungary, Latvia, Russian... and more
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of Tapentadol ER Compared With Placebo in Patients With Chronic, Painful Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy

United States, Canada, Puerto Rico
Pfizer

Terminated

Open Label Sumanirole Study of Safety, Tolerability, and Therapeutic Response In Patients With Parkinson's Disease

Parkinson Disease

Colombia, United States, Argentina, Puerto Rico
Biogen

Active, not recruiting

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy (DEVOTE)

Muscular Atrophy, Spinal

China, United States, Netherlands, Spain, Korea, Republic of, Taiwan, Australia, Canada, Chile, Saudi Arabia, Poland, Israel, Brazil, Russian Federation, Hungary, Japan, United Kingdom, Italy, Germany, Estonia, Greece, Mexico, Colombia and more
Novartis Pharmaceuticals
Amgen; Banner Alzheimer's Institute

Terminated

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease (GS2)

Alzheimers Disease

Spain, United States, Belgium, Italy, Germany, Australia, Israel, Taiwan, Japan, Canada, Korea, Republic of, United Kingdom, France, China, Argentina, Finland, Singapore, Portugal, Chile, Mexico, Switzerland, Netherlands, Iceland, Puerto... and more
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity in Adults of Revaccination With Adacel® Vaccine 10 Years After a Previous Dose

Pertussis | Whooping Cough | Tetanus | Diphtheria

United States, Canada
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of Tdap Vaccine Compared to DTaP Vaccine in Children 4 to 6 Years of Age

Pertussis | Tetanus | Diphtheria

United States, Canada
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

Evaluation of Vitrectomy for Diabetic Macular Edema (Vitrectomy-D)

Diabetic Retinopathy | Diabetic Macular Edema

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; Allergan

Completed

Laser-Ranibizumab-Triamcinolone for Diabetic Macular Edema (LRT for DME)

Diabetic Retinopathy | Diabetic Macular Edema

United States
Edixomed Ltd
Queen Mary University of London

Completed

Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers (ProNOx1)

Diabetic Foot Ulcer

United Kingdom
Sun Pharma Advanced Research Company Limited

Active, not recruiting

PROSEEK: A Phase 2 Study In Early Parkinson's Disease Patients Evaluating The Safety And Efficacy Of Abl Tyrosine Kinase Inhibition Using K0706

Early Parkinson Disease

United States, Spain, India, Hungary, Slovakia, Poland
Adaptive Phage Therapeutics, Inc.
United States Department of Defense

Recruiting

Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis (DANCE)

Diabetic Foot Osteomyelitis | Osteomyelitis

United States
Teijin America, Inc.

Completed

Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria

Diabetic Kidney Disease

United States
CSL Behring

Completed

Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks

Hereditary Angioedema

Bulgaria, United States, Poland, Spain, Hungary, United Kingdom, Russian Federation, Macedonia, The Former Yugoslav Republic of, Argentina, Australia, Canada, Czech Republic, Israel, Romania, Sweden
Biotie Therapies Inc.

Terminated

Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients (TOZ-PD)

Idiopathic Parkinson's Disease

Germany, Spain, Canada, United States, Italy, Austria, Czechia
Eisai Inc.

Completed

Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies

Dementia With Lewy Bodies

United States, Spain, France, Germany, Italy, Japan, United Kingdom
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Recruiting

Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) (ADNI3)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD)

United States, Canada
Adamas Pharmaceuticals, Inc.

Terminated

Efficacy and Safety of Amantadine Hydrogen Chloride (HCl) ER Tablets in Parkinson's Disease Subjects With LID (ALLAY-LID-II)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

France, Germany, Canada, United States, Spain
St George Street Capital

Completed

AZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19 (ARCADIA)

Covid19

Czechia, Romania, United Kingdom
Laboratoires URGO

Unknown

Assessment of the Efficacy and Safety of a New Medical Device in the Local Treatment of Diabetic Foot Ulcers (DISCOVERY)

Diabetic Foot Ulcer

Czechia, France, Italy, Poland, Spain, United Kingdom
Intellia Therapeutics

Active, not recruiting

NTLA-2002 in Adults With Hereditary Angioedema (HAE) (NTLA-2002)

Hereditary Angioedema

France, New Zealand, Germany, United Kingdom, Netherlands, Australia
Oxford University Hospitals NHS Trust

Active, not recruiting

AI Assisted Detection of Chest X-Rays (AID-CXR)

Pneumoperitoneum | Pneumothorax | Cardiomegaly | Pleural Effusion | Atelectasis | Pulmonary Nodules, Solitary | Pneumothorax; Acute | Pleural Effusions, Chronic | Pulmonary Nodules, Multiple | Fibrosis Lung | Pulmonary Consolidation | Pulmonary Calcification

United Kingdom
Allergan

Terminated

A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis 01

Diabetes Mellitus | Gastroparesis

United States, Australia, India, Thailand, Korea, Republic of, Malaysia, Spain, Singapore, Israel, Poland, Bulgaria, France, Philippines, Ukraine
ACADIA Pharmaceuticals Inc.

Terminated

The INSYTE (Management of Parkinson's Disease Psychosis in Actual Practice) Study

Parkinson Disease Psychosis

United States
GlaxoSmithKline

Completed

A Study to Assess the Effect of Repeat Doses of GSK962040 on the Pharmacokinetics of L-DOPA in Subjects With Parkinson's Disease Exhibiting Delayed Gastric Emptying

Gastroparesis

Germany, Australia, Sweden, United Kingdom
Boehringer Ingelheim

Completed

Pivotal Study in Advanced Parkinsons Disease Patients

Parkinson Disease

Austria, Czech Republic, Hungary, India, Italy, Korea, Republic of, Philippines, Poland, Russian Federation, Slovakia, Spain, Sweden, Ukraine, United Kingdom
Boehringer Ingelheim

Completed

Long-term Safety Study of Open-label Pramipexole ER in Patients With Advanced PD

Parkinson Disease

Austria, Czech Republic, Hungary, India, Italy, Korea, Republic of, Philippines, Poland, Russian Federation, Slovakia, Spain, Sweden, Ukraine, United Kingdom
Artios Pharma Ltd

Recruiting

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

Ovarian Cancer | Fallopian Tube Cancer | Metastatic Cancer | Advanced Cancer | Primary Peritoneal Cancer

United States, Spain, United Kingdom, France
University of South Florida
National Cancer Institute (NCI)

Completed

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Brain Tumor | Cachexia | Myelodysplastic/Myeloproliferative Diseases | Central Nervous System Tumors

United States, Canada, Puerto Rico
Boehringer Ingelheim

Completed

Efficacy, Safety, Tolerability of Pramipexol ER Versus Pramipexol IR Versus Placebo in Early PD Patients

Early Parkinson Disease (Early PD)

United States, Argentina, Austria, Czech Republic, Finland, Germany, Hungary, India, Japan, Malaysia, Russian Federation, Slovakia, Taiwan, Ukraine

Clinical Trials on Acidosis, Metabolic in United States

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