Clinical Trials on Acrosome Reaction in Canada

Total 266 results

Universidad de Granada

Enrolling by invitation

Telehealth Program to Prevent Cancer and Chemotherapy-related Cognitive Impairment.

Breast Neoplasms

Spain
XDx

Terminated

Lung Allograft Rejection Gene Expression Observational (LARGO) Study (LARGO)

Lung Disease | Graft Rejection

United States, Canada, Germany, Austria, United Kingdom
Sunnybrook Health Sciences Centre
University Health Network, Toronto; McMaster University; London Health Sciences...

Recruiting

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients (CODEX)

Mental Disorders | Nervous System Diseases | Neurologic Manifestations | Delirium | Confusion | Neurobehavioral Manifestations | Neurocognitive Disorders | Cognitive Dysfunction | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Signs and Symptoms | Physiological Effects of Drugs | Analgesics,... and other conditions

Canada
Masaryk University

Recruiting

COVID-19 Vaccines Safety Tracking (CoVaST)

Adverse Reaction to Vaccine | COVID19 Vaccine

Poland, Canada, United States, Croatia, Czechia, Estonia, Ethiopia, Germany, Ghana, Mexico, Portugal, Russian Federation, Serbia, Slovenia
AstraZeneca

Completed

Study of Verinurad in Heart Failure With Preserved Ejection Fraction (AMETHYST)

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States, Germany, Canada, Korea, Republic of, Austria, Slovakia, Australia, Bulgaria, Russian Federation, Argentina, Poland, Mexico
Kayseri City Hospital

Completed

The Effect of Azithromycin Use on Conduction System of Heart in COVID-19 Positive Children

Covid19 | Long QT Syndrome | Azithromycin Adverse Reaction

Turkey
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
University of British Columbia

Completed

Deep Brain Stimulation for Voice Tremor: Left, Right, or Both Hemispheres? (EVT)

Laryngeal Diseases | Essential Tremor | Deep Brain Stimulation | Action Tremor | Essential Voice Tremor | Tremor, Nerve

Canada
Baskent University Ankara Hospital

Completed

Oxygen Reserve Index and Prevention of Hyperoxemia

Hyperoxia | Oxygen Reserve Index | Hyperoxemia | Fraction of Inspired Oxygen

Turkey
Genzyme, a Sanofi Company

Completed

Evaluation of Thymoglobulin Induction and Reduced Doses of Calcineurin Inhibitors on Liver Transplant Rejection

Liver Dysfunction | Transplantation, Liver | Rejection, Transplant

United States, Canada
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
XDx

Completed

Cardiac Allograft Rejection Gene Expression Observational (CARGO) II STUDY (CARGOII)

Heart Disease | Graft Rejection

United States, Canada, United Kingdom, Austria, Belgium, France, Germany, Italy, Poland, Spain, Switzerland
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

Graft Rejection | Kidney Failure

United States, Spain, Canada, Switzerland, Austria, Australia, New Zealand
Dr. Negrin University Hospital
University of Las Palmas de Gran Canaria

Completed

Prevention of Perioperative Hypothermia in Patients Submitted to Transurethral Resection

Hypothermia; Anesthesia | Temperature Change, Body | Perioperative/Postoperative Complications | Complication of Anesthesia | Transurethral Resection Syndrome | Anaesthesia Complication

Spain
Montreal Heart Institute
AstraZeneca

Recruiting

Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (CarChem)

Lymphoma | Leukemia | Breast Cancer

Canada
Université de Sherbrooke
McMaster University

Recruiting

Calcineurin Inhibitor in NEuRoloGically Deceased Donors to Decrease Kidney delaYed Graft Function (CINERGY) (CINERGY)

Ischemic Reperfusion Injury | Brain Death | Organ Transplant Failure or Rejection

Canada
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant (CLEAR Serenity)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease | Statin Adverse Reaction

United States, Canada
James Chodosh, MD, MPH
Massachusetts Eye and Ear Infirmary; Fonds de recherche en ophtalmologie de...

Withdrawn

Topical Infliximab in Autoimmune Eyes With Keratoprosthesis

Stevens-Johnson Syndrome | Mucous Membrane Pemphigoid | Toxic Epidermal Necrolysis (Lyell) Syndrome

United States, Canada
Bristol-Myers Squibb

Completed

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT (EMBARK-HFpEF)

Heart Failure With Preserved Ejection Fraction

Canada, United States, Ireland
Novartis Pharmaceuticals

Completed

Description of Tolerability of LCZ696 (Sacubitril / Valsartan) in Heart Failure With Reduced Ejection Fraction (HFrEF) Treated in Real Life Setting (PARASAIL)

Hearth Failure With Reduced Ejection Fraction (HFrEF)

Canada
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Treatment of Acute Lymphoblastic Leukemia in Children

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
AstraZeneca

Terminated

JUPITER - Crestor 20mg Versus Placebo in Prevention of Cardiovascular (CV) Events

Elevated High-sensitivity C-Reactive Protein (hsCRP)

United States, Brazil, Bulgaria, Poland, Russian Federation, South Africa, United Kingdom, Germany, Estonia, Romania, Denmark, Netherlands, Norway, Canada, Mexico, Belgium, Israel, Puerto Rico, Colombia, Argentina, Venezuela, Panama, Urugu... and more
Cytokinetics

Completed

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure (METEORIC-HF)

Heart Failure With Reduced Ejection Fraction

United States, Hungary, France, Canada, Netherlands, Germany, Poland, Italy, Sweden
AstraZeneca

Completed

DETERMINE-reduced - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Reduced Ejection Fraction

Heart Failure With Reduced Ejection Fraction (HFrEF)

United States, Canada, Denmark, Korea, Republic of, Brazil, Slovakia, Japan, South Africa, Sweden
Novartis Pharmaceuticals

Completed

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION)

Heart Failure With Reduced Ejection Fraction

Italy, Czechia, Russian Federation, Saudi Arabia, Turkey, Belgium, Switzerland, United Kingdom, Spain, Canada, Lebanon, Germany, Slovakia, Portugal, France, Poland, Argentina, Norway, Sweden
AstraZeneca

Completed

DETERMINE-preserved - Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States, Denmark, Italy, Canada, Korea, Republic of, Brazil, Slovakia, Japan, Bulgaria, South Africa, Sweden, Argentina
AstraZeneca

Completed

Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40% (ENDEAVOR)

Heart Failure With Preserved Ejection Fraction

United States, France, Netherlands, Belgium, Taiwan, Slovakia, Japan, Czechia, Hungary, Australia, Bulgaria, Poland, Russian Federation, Brazil, Denmark, Turkey, Sweden, Canada
Novartis Pharmaceuticals

No longer available

Multiple Patient Program to Ensure Access to LCZ696 Treatment to Patients Diagnosed With Heart Failure With Reduced Ejection Fraction (HF-rEF)

Heart Failure With Reduced Ejection Fraction (HF-rEF)

Germany, Spain, France, Greece, Lebanon, Austria, Ireland, Slovenia, Australia, Philippines, Brazil, Panama, United States, Croatia, Cyprus, Malta, Switzerland, United Arab Emirates
Novartis Pharmaceuticals

Completed

Changes in NT-proBNP, Safety, and Tolerability in HFpEF Patients With a WHF Event (HFpEF Decompensation) Who Have Been Stabilized and Initiated at the Time of or Within 30 Days Post-decompensation (PARAGLIDE-HF)

Heart Failure With Preserved Ejection Fraction (HFpEF)

United States, Canada
Bayer
Merck Sharp & Dohme LLC; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF (VITALITY-HFpEF)

Chronic Heart Failure With Preserved Ejection Fraction

Spain, United States, Belgium, Singapore, Taiwan, Canada, Japan, Italy, Austria, Bulgaria, Germany, Greece, Israel, Poland, Portugal, Hungary, Russian Federation, Argentina, Colombia, Malaysia, South Africa
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF Patients (PARALLAX)

Heart Failure With Preserved Ejection Fraction

Colombia, Romania, United States, Austria, Belgium, Estonia, Turkey, Germany, Netherlands, Italy, Spain, Thailand, Argentina, France, Bulgaria, Hungary, Israel, Peru, Lithuania, Guatemala, India, Russian Federation, Denmark, Mexico, Slo... and more
Eli Lilly and Company

Recruiting

A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

Heart Failure | Heart Failure With Preserved Ejection Fraction

Spain, United States, Japan, United Kingdom, Czechia, Hungary, Israel, Brazil, Argentina, Canada, Poland, Turkey
AstraZeneca

Active, not recruiting

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone (REALIZE-K)

Heart Failure With Reduced Ejection Fraction | Hyperkalaemia

United States, Spain, Canada, Brazil, Hungary, Czechia, Ukraine, Poland, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction (PARAGON-HF)

Heart Failure With Preserved Ejection Fraction

China, Germany, United States, Colombia, South Africa, Italy, Austria, Belgium, Croatia, Romania, Taiwan, Japan, Netherlands, Denmark, France, Israel, Spain, Switzerland, Korea, Republic of, Argentina, Canada, United Kingdom, Bulgaria, Gree... and more
Novartis Pharmaceuticals

Completed

randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure (OUTSTEP-HF)

Chronic Heart Failure With Reduced Ejection Fraction

Belgium, Estonia, Denmark, Greece, United Kingdom, Germany, Latvia, Lithuania, Spain, Netherlands, Bulgaria, Finland, Poland, Czechia, Iceland, Sweden, France, Ireland, Norway
Abbott Medical Devices

Completed

Hemodynamic-GUIDEd Management of Heart Failure (GUIDE-HF)

Heart Failure | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure With Reduced Ejection Fraction | Heart Failure NYHA Class IV | Heart Failure With Normal Ejection Fraction | Heart Failure; With Decompensation | Heart Failure...

United States, Canada
AstraZeneca

Completed

Dapagliflozin Evaluation to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure. (DELIVER)

Heart Failure With Preserved Ejection Fraction

United States, Canada, Belgium, Czechia, Hungary, Taiwan, Vietnam, Mexico, Peru, China, Japan, Bulgaria, Spain, Brazil, Saudi Arabia, Netherlands, Romania, Russian Federation, Poland, Argentina
Thunder Bay Regional Health Research Institute
Lakehead University; St. Joseph's Care Group; Thunder Bay Regional Health Sciences...

Recruiting

Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders

Bronchiectasis | Chronic Obstructive Pulmonary Disease | Asthma | Obstructive Sleep Apnea | Emphysema | Pulmonary Fibrosis | Lung Cancer | Cystic Fibrosis | Mesothelioma | Pulmonary Hypertension | Interstitial Lung Disease | Pulmonary Embolism | Lung Resection | Lung Transplant | Seasonal Allergies | Lung Infection | Asbes... and other conditions

Canada
Fundación Centro Nacional de Investigaciones Cardiovasculares...
European Commission

Recruiting

REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Lymphoma | Anthracycline-induced Cardiac Toxicity

Netherlands, Spain, Denmark, Germany, France, Portugal
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Biafine Cream to Reduce Side Effects of Radiation Therapy in Patients Receiving Treatment for Advanced Head and Neck Cancer

Head and Neck Cancer | Skin Reactions Secondary to Radiation Therapy

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States, Canada, Switzerland
Novartis Pharmaceuticals

Completed

Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

India, Romania, Belgium, Czechia, Estonia, Hungary, Russian Federation, Taiwan, United Kingdom, Spain, Israel, Thailand, Canada, Korea, Republic of, United States, Bulgaria, Denmark, Netherlands, Philippines, Lithuania, Germany, T... and more
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035) (VICTOR)

Chronic Heart Failure With Reduced Ejection Fraction

China, United States, Argentina, Australia, Austria, Brazil, Canada, Chile, Colombia, Czechia, Denmark, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Ireland, Israel, Italy, Korea, Republic of, Malaysia, Mexico, New Zealand, Peru and more
Pfizer

Terminated

Global Prevalence of ATTR-CM in Participants With HFpEF

Heart Failure With Preserved Ejection Fraction | Transthyretin Amyloid Cardiomyopathy

Spain, United States, Japan, Canada, France, Italy, Poland, United Kingdom
Novartis Pharmaceuticals

Terminated

This Study Will Evaluate the Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality of Patients With Chronic Heart Failure (PARADIGM-HF)

Heart Failure With Reduced Ejection Fraction

China, Germany, United States, Colombia, Korea, Republic of, Romania, South Africa, Canada, Belgium, Estonia, Hungary, Italy, Russian Federation, Taiwan, Turkey, United Kingdom, Spain, France, Netherlands, Hong Kong, Bulgaria, Israel and more
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin

Unspecified Childhood Solid Tumor, Protocol Specific | Ototoxicity

Canada, United States, Australia
Novartis Pharmaceuticals

Completed

Open Label, Safety, Tolerability and Efficacy of AFQ056 in Parkinson's Patients With L-dopa Induced Dyskinesias

Parkinson Disease | Dyskinesia, Drug-Induced | Levodopa

Italy, United States, Australia, France, Germany, Canada
AstraZeneca

Completed

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure (DAPA-HF)

Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)

United States, Canada, Denmark, United Kingdom, Czechia, Vietnam, Germany, Brazil, India, China, Japan, Taiwan, Netherlands, Bulgaria, Slovakia, Hungary, Poland, Russian Federation, Argentina, Sweden

Clinical Trials on Acrosome Reaction in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Panama

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations