Clinical Trials on Activating Mutations
Total 1065 results
-
Abramson Cancer Center at Penn MedicineActive, not recruitingAdvanced Breast Cancer | Metastatic Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Locally Advanced Breast CancerUnited States
-
AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
-
Institut CurieCompletedWomen With BRCA1 Germline Deleterious MutationFrance
-
Sarcoma Oncology Research Center, LLCAadi Bioscience, Inc.CompletedMelanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Ewing Sarcoma | Non Small Cell Lung Cancer | Chordoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | PEComa | Desmoid Tumor | Epithelioid Sarcoma | Squamous Cell Carcinoma | MTOR Activating MutationUnited States
-
University Health Network, TorontoSuspendedBreast Cancer | Breast Diseases | Genetic Predisposition to Disease | Surgery | Surgery--Complications | BRCA1 Mutation | BRCA2 MutationCanada
-
Northwestern UniversityNorthwestern Memorial Hospital; Saint Joseph Hospital, Chicago, IllinoisRecruitingBreast Cancer | BRCA MutationUnited States
-
Johns Hopkins UniversityCompletedChronic Low-back Pain | Patient ActivationUnited States
-
City of Hope Medical CenterNational Cancer Institute (NCI)CompletedMLH1 Gene Mutation | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Metastatic Carcinoma in the Liver | MSH6 Gene Mutation | PMS2 Gene MutationUnited States
-
Gunnar LachmannCompletedHemophagocytic Lymphohistiocytosis (HLH) | Macrophage Activation Syndrome (MAS) | Hemophagocytic Syndromes
-
San Raffaele UniversityUnita' di Gastroenterologia - Policlinico Universitario di Bari; Unita' di... and other collaboratorsRecruitingLynch Syndrome | MLH1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | Lynch Syndrome II | Small Bowel Adenocarcinoma | Lynch Syndrome IItaly
-
The First Affiliated Hospital of Guangzhou Medical...Unknown
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedInvasive Breast Carcinoma | HER2/Neu Negative | Breast Adenocarcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene MutationUnited States
-
Seoul National University HospitalBayer; Korean Society of Breast Imaging & Korean Society For Breast ScreeningUnknownBreast Cancer | BRCA1 Mutation | BRCA2 Mutation | Recurrent Breast Cancer | Metachronous NeoplasmKorea, Republic of
-
Assistance Publique - Hôpitaux de ParisNot yet recruiting
-
Jiangxi Qingfeng Pharmaceutical Co. Ltd.UnknownBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationChina
-
Beijing Friendship HospitalNot yet recruitingMacrophage Activation Syndrome
-
University of Alabama at BirminghamActive, not recruitingMacrophage Activation SyndromeUnited States
-
University of ThessalyCompletedSkeletal Muscle Performance | Skeletal Muscle Damage | Exercise-induced Aseptic Inflammation | Intracellular Signaling in Skeletal Muscle | Proteasome ActivationGreece
-
Peking University People's HospitalUnknownMacrophage Activation SyndromeChina
-
Jewish General HospitalUniversity of Manitoba; McGill University Health Centre/Research Institute... and other collaboratorsRecruitingLow Anterior Resection Syndrome | Rectal Cancer | Surgery | Patient Activation | Low Anterior ResectionCanada, United States
-
Mayo ClinicAllerganCompletedNeoplasms | Pain, Postoperative | Breast Cancer | Breast Diseases | BRCA1 Mutation | BRCA2 MutationUnited States
-
University Medical Centre LjubljanaUniversity of Ljubljana, Faculty of Medicine; National Institute of Chemistry... and other collaboratorsCompletedCTNNB1 Gene MutationSlovenia, Australia
-
University of MichiganCompletedWomen With BRCA 1 or BRCA 2 Mutation | Non-tested Female Family MembersUnited States
-
Kura Oncology, Inc.AvailableAcute Lymphoblastic Leukemia, With Appropriate Mutations | Acute Myeloid Leukemia, With NPM1 Mutations
-
NYU Langone HealthRecruitingMLH1 Gene Mutation | RAD51C Gene Mutation | BRIP1 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | BRCA-Mutated Ovarian Carcinoma | MSH2 A636P | EPCAMUnited States
-
University of UtahTerminatedPrimary Myelofibrosis | Anemia | Thrombocytopenia | Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma | IDH2 Gene Mutation | IDH1 Gene Mutation | Secondary Myelofibrosis | ASXL1 Gene Mutation | EZH2 Gene MutationUnited States
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBreast Carcinoma | Fallopian Tube Carcinoma | Endometrial Carcinoma | Ovarian Carcinoma | Primary Peritoneal Carcinoma | Deleterious CDH1 Gene Mutation | Deleterious DICER1 Gene Mutation | Deleterious SMARCA4 Gene Mutation | Deleterious STK11 Gene MutationUnited States
-
The First Affiliated Hospital of Soochow UniversityUnknown
-
Novartis PharmaceuticalsRecruitingRare Unresectable or Metastatic BRAF V600E Mutation-positive Solid TumorsUnited States
-
European Organisation for Research and Treatment...AstraZenecaWithdrawnBRCA1 Mutation | BRCA2 Mutation | TNBC - Triple-Negative Breast Cancer
-
Sun Yat-sen UniversityNot yet recruitingNSCLC | BRAF V600 Mutation | MET Exon 14 MutationChina
-
Poitiers University HospitalCompletedMast Cell Activation Syndrome | Urticaria Pigmentosa | Mast Cell Activation Disease | Mast Cell DiseaseFrance
-
Tianjin Medical University Second HospitalJiangsu HengRui Medicine Co., Ltd.UnknownSolid Tumor | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein OverexpressionChina
-
AstraZenecaNo longer available
-
Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 MutationUnited Kingdom
-
Memorial Sloan Kettering Cancer CenterCompletedBreast Cancer | Metastatic Breast Cancer | Breast Cancer Stage IV | Solid Carcinoma | HER2-negative Breast Cancer | MEK1 Gene Mutation | MEK2 Gene MutationUnited States
-
Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NFE2L2 Gene Mutation | NRF2 MutationUnited States
-
Severance HospitalSamsung Medical Center; Changhua Christian Hospital; European Institute of OncologyCompletedRecurrence | Postoperative Complications | Breast Cancer | Breast Neoplasms | Surgery | Surgery--Complications | BRCA1 Mutation | BRCA2 MutationKorea, Republic of
-
Centre Hospitalier Universitaire, AmiensRecruitingPlatelet Aggregation | Heparin-induced Thrombocytopenia | Platelet Activation | Platelet DisorderFrance
-
University Hospital, RouenUnknown
-
Institut Claudius RegaudRecruiting
-
Rana McKay, MDUniversity of California, San Diego; AstraZenecaRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Adenocarcinoma | High-Risk CancerUnited States
-
Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NRF2 Gene Mutation | NFE2L2 Gene MutationUnited States
-
Yongchang ZhangRecruitingHER2 Insertion Mutation Positive Advanced NSCLCChina
-
ETOP IBCSG Partners FoundationAstraZenecaActive, not recruitingNSCLC Stage IV | EGFR Gene MutationSingapore, Sweden, Korea, Republic of, Spain, Switzerland, Netherlands, Italy, Poland
-
Rigshospitalet, DenmarkCompletedCardiomyopathies | TTN | Truncation MutationDenmark
-
Akdeniz UniversityRecruitingWeb-based Mobile Health Application for Patients With Liver Cirrhosis (ReLiver-N App) (ReLiver-NApp)Liver Cirrhosis | Mobile Health | Patient ActivationTurkey
-
Institut BergoniéRecruitingPTEN Gene MutationFrance
-
National University of MalaysiaRecruitingin Vitro Maturation | Cumulus Cell | Increased Oocyte Death | GREM1 Gene MutationMalaysia
-
Georgetown UniversityCompletedPancreatic Cancer | Breast Neoplasm | BRCA1 Mutation | BRCA2 Mutation | Prostate CarcinomaUnited States