Clinical Trials on Active Immune Response in Czechia

Total 1212 results

Fresenius Kabi SwissBioSim GmbH

Completed

MSB11456 in Participants With Moderately to Severely Active Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary, Serbia, Georgia, Russian Federation, Slovakia, Czechia, Bulgaria, Moldova, Republic of, Poland
Ablynx

Completed

A Phase II Study to Evaluate Safety and Efficacy of ALX-0061 in Subjects With Systemic Lupus Erythematosus

Lupus Erythematosus, Systemic

United States, Hungary, Spain, Philippines, Poland, Serbia, Argentina, Chile, Czechia, Germany, Korea, Republic of, Mexico, Peru, Portugal, Russian Federation, Taiwan, Ukraine
Debiopharm International SA

Completed

Study to Evaluate the Efficacy and Tolerability of Debio 1562 in Combination With Rituximab in Participants With Relapsed and/or Refractory DLBCL and Other Forms of NHL

Diffuse Large B-Cell Lymphoma | B-cell Non-Hodgkin's Lymphoma

United States, Czechia, Bulgaria, Belgium, Hungary, Ukraine, Italy, Poland, Switzerland
Biogen
AbbVie

Completed

Safety and Efficacy Extension Study of Daclizumab High Yield Process (DAC HYP) (BIIB019) in Participants Who Have Completed Study 205MS202 (NCT00870740) to Treat Relapsing Remitting Multiple Sclerosis (SELECTED)

Relapsing-Remitting Multiple Sclerosis

Germany, Hungary, Czechia, Russian Federation, India, Poland, Ukraine, United Kingdom
Boehringer Ingelheim

Terminated

BI 695500 vs Rituxan First Line Treatment in Patients With Low Tumor Burden Follicular Lymphoma

Lymphoma, Non-Hodgkin

Austria, Belgium, United States, Bulgaria, Croatia, Czech Republic
Avigen

Terminated

Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis

Muscle Spasticity

Czech Republic, Ukraine, Germany, Russian Federation, Serbia
Janssen Research & Development, LLC
Pharmacyclics LLC.

Active, not recruiting

A Study of Ibrutinib With Rituximab in Relapsed or Refractory Mantle Cell Lymphoma (VEGA)

Lymphoma, Mantle-Cell

Taiwan, Thailand, Malaysia, India, Puerto Rico, Spain, Turkey, Czechia, Brazil, Greece, Poland, Sweden, Romania
Jazz Pharmaceuticals

Terminated

Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple Sclerosis (RELEASE MSS3)

Multiple Sclerosis (MS)

United States, Poland, Czechia, United Kingdom, Romania
Idorsia Pharmaceuticals Ltd.

Recruiting

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus (OPUS-2)

Lupus Erythematosus, Systemic

Spain, United States, Georgia, Serbia, Germany, Portugal, Poland, South Africa, Philippines, Czechia, Puerto Rico, Chile, Japan, Mexico, Peru
EMD Serono

Terminated

Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)

Lupus Erythematosus, Systemic

United States, Korea, Republic of, Bulgaria, Argentina, Mexico, Italy, Spain, Philippines, Germany, Czechia, Chile, Poland, Peru, United Kingdom, South Africa, Brazil, Russian Federation
LEO Pharma

Completed

Tralokinumab in Combination With Topical Corticosteroids in Subjects With Severe Atopic Dermatitis - ECZTRA 7 (ECZTRA 7)

Atopic Dermatitis

Belgium, France, Germany, Poland, United Kingdom, Czechia, Spain
AstraZeneca
Iqvia Pty Ltd

Terminated

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

United States, France, Korea, Republic of, Spain, Czechia, Bulgaria, Australia, Poland
Janssen Research & Development, LLC

Completed

An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Poland, Argentina, Colombia, Philippines, Russian Federation, Thailand, Czech Republic
BeiGene

Completed

Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma (MAGNOLIA)

Marginal Zone Lymphoma | MZL

China, Australia, Italy, France, New Zealand, Czechia, United Kingdom, United States, Korea, Republic of
Pfizer

Completed

Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Poland, Bulgaria, Australia, Belgium, Hungary, Spain, United Kingdom, Czechia, Slovakia, Germany, Mexico, Philippines, Russian Federation, South Africa
Novartis Pharmaceuticals

Terminated

Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma

Asthma

Germany, United States, Belgium, Poland, Latvia, Argentina, Czechia, Russian Federation, Japan, Hungary, Bulgaria, Philippines, Slovakia, Canada
Diamyd Medical AB

Recruiting

A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes (DIAGNODE-3)

Type 1 Diabetes Mellitus

Czechia, Spain, United States, Hungary, Netherlands, Estonia, Germany, Poland, Sweden
Eli Lilly and Company
Rigel Pharmaceuticals

Recruiting

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, France, United Kingdom, Argentina, Mexico, India, Czechia, Germany, Slovakia
AbbVie

Completed

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Rheumatoid Arthritis

United States, Bulgaria, Chile, Czechia, Hungary, Israel, Latvia, Mexico, Poland, Puerto Rico, Russian Federation, Slovakia, South Africa, Spain, Turkey, Ukraine
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Rheumatoid Arthritis

United States, Argentina, Belgium, Brazil, Czechia, Estonia, Finland, Hungary, Israel, Italy, Mexico, Netherlands, Poland, Romania, Russian Federation, Spain, Sweden, United Kingdom, Norway
EMD Serono

Terminated

STRIDE - STimulating Immune Response In aDvanced brEast Cancer (STRIDE)

Breast Cancer

Czech Republic, Korea, Republic of, Russian Federation, South Africa, Germany, Slovakia, Austria, United States, Belgium, Poland, Israel, Australia
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United Kingdom, Taiwan, Spain, Korea, Republic of, Belgium, Russian Federation, Czech Republic, Netherlands, Ireland
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Rheumatoid Arthritis

Poland, Croatia, Russian Federation, Bulgaria, Czech Republic, Former Serbia and Montenegro, Slovakia, Slovenia, Ukraine
Hoffmann-La Roche

Active, not recruiting

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)

Relapsing Multiple Sclerosis | Primary Progressive Multiple Sclerosis

Spain, United States, Italy, Poland, Turkey, New Zealand, Czechia, Brazil
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL) (CheckMate 647)

Lymphoma

United States, Canada, Hong Kong, Italy, Japan, France, Israel, Germany, Hungary, Brazil, Czechia, Russian Federation, Singapore
Novo Nordisk A/S

Completed

Efficacy of NNC109-0012 in Subjects With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

United Kingdom, Italy, Poland, Portugal, Spain, Germany, Czech Republic, Romania
Novo Nordisk A/S

Completed

Comparison of Insulin Aspart Produced by the NN2000 Process to the Current Process in Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Poland, Germany, Italy, Hungary, Czech Republic
Hoffmann-La Roche

Completed

A Study of Lebrikizumab (RO5490255) in Participants With Severe Oral Corticosteroids (OCS) Dependent Asthma

Asthma

Spain, Belgium, United States, Canada, United Kingdom, France, Netherlands, Australia, New Zealand, Puerto Rico, Poland, Mexico, Slovakia, Slovenia, Czechia, Denmark
Janssen-Cilag International NV

Completed

Velcade Consolidation Bone Study

Multiple Myeloma

Turkey, Greece, Czech Republic, Austria, Germany, Sweden, United Kingdom, Denmark
Lexicon Pharmaceuticals

Completed

Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Hungary, Poland, Serbia
Sanofi

Completed

Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Plasma Cell Myeloma

France, Italy, Czechia, Greece, Spain, Canada, Australia, United States, Brazil, Hungary
AEterna Zentaris
Dana-Farber Cancer Institute

Terminated

Assessment of Efficacy and Safety of Perifosine, Bortezomib and Dexamethasone in Multiple Myeloma Patients

Multiple Myeloma

Israel, Spain, Korea, Republic of, United States, Russian Federation, Canada, Ireland, Czechia, Slovakia
Acerta Pharma BV

Active, not recruiting

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Mantle Cell Lymphoma (MCL)

Belgium, France, United Kingdom, United States, Italy, Poland, Netherlands, Australia, Czechia, Spain
Fujifilm Kyowa Kirin Biologics Co., Ltd.

Completed

A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients (ARABESC-OLE)

Arthritis, Rheumatoid

Poland, Russian Federation, United States, Germany, Romania, Ukraine, Canada, Chile, Czechia, Spain, Peru
Novo Nordisk A/S

Completed

Safety Follow-up on Children and Adolescents With Type 1 Diabetes Treated With Insulin Detemir. An Extension to Trial NN304-1689

Diabetes | Diabetes Mellitus, Type 1

France, Denmark, Finland, Russian Federation, Macedonia, The Former Yugoslav Republic of, Hungary, Bulgaria, United Kingdom, Turkey, Czech Republic, Poland
UCB Biopharma SRL

Enrolling by invitation

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Argentina, Belgium, Bulgaria, Canada, Chile, Czechia, Germany, Greece, Hungary, Mexico, Poland, Romania, Serbia, Spain, Taiwan, Colombia, Italy, Korea, Republic of, Peru, Philippines
Novartis Pharmaceuticals

Terminated

Systemic Corticosteroids Avoidance Study in Severe Asthma Patients

Asthma

Germany, Belgium, South Africa, United States, Russian Federation, France, Slovakia, Spain, Thailand, Czechia, Greece, Argentina, Peru, United Kingdom, Bulgaria, Turkey, Hungary, Vietnam, Philippines, Colombia, Chile
Sanofi

Completed

Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus (CLEan)

Cutaneous Lupus Erythematosus

Chile, Italy, Czechia, Mexico, Spain, Ukraine, United States, Argentina, Australia, Canada, Hungary, India, Poland, Russian Federation, United Kingdom
Associazione Angela Serra per la ricerca sul cancro
Fondazione Italiana Linfomi ONLUS; The International Non-Hodgkin Lymphoma Prognostic...

Completed

Study of Prognosis of Follicular Lymphoma Through a Prospective Collection of Data (F2-study)

Lymphoma, Follicular

United States, Spain, Italy, Switzerland, United Kingdom, Argentina, Czechia, France
Hoffmann-La Roche
AbbVie

Completed

A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax Combined With Chemotherapy in Participants With B-Cell Non-Hodgkin's Lymphoma (NHL) and DLBCL

Lymphoma, Non-Hodgkin

Spain, Hungary, United States, Canada, Australia, Austria, Czechia, France, Italy, Netherlands
Biogen

Completed

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis (OBSERVE)

Relapsing-Remitting Multiple Sclerosis

Poland, Hungary, United States, Czech Republic
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Hodgkin's Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Canada, United States, Brazil, Czechia, France, Italy, Poland, Russian Federation, South Africa, Turkey, Ukraine
UCB Pharma

Completed

A Study of Liquid Certolizumab Pegol as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Poland, Israel, Bulgaria, Serbia, Ukraine, Chile, Russian Federation, Lithuania, Mexico, Czechia, Latvia, Croatia, Estonia, Slovakia
Seagen Inc.

Active, not recruiting

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Peripheral T-cell Lymphoma

United States, Czechia, Italy, Spain, United Kingdom, France
Merck KGaA, Darmstadt, Germany

Completed

Evaluation of the Onset of Action in Highly Active MS (MAGNIFY)

Multiple Sclerosis

United Kingdom, Germany, Israel, Finland, Canada, Australia, Czechia, Spain, France, Italy, Austria, Hungary, Poland, Sweden
Bayer

Completed

BENEFIT 15 Long-term Follow-up Study of the BENEFIT and BENEFIT Follow-up Studies

Multiple Sclerosis

Spain, Belgium, Czechia, Italy, United Kingdom, Hungary, Germany, Switzerland, Austria, France, Poland, Canada, Sweden, Finland, Israel, Denmark, Norway, Portugal
Incyte Corporation

Recruiting

Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (firmMIND) (firmMIND)

Diffuse Large B-Cell Lymphoma | Large B-Cell Lymphoma

Croatia, Serbia, Czechia, Finland, Israel, Romania, Denmark, Hungary, Ireland, Poland, Turkey, Bulgaria, Norway, United Kingdom
Baxalta now part of Shire
Takeda Development Center Americas, Inc.

Completed

Long-Term Tolerability and Safety of HYQVIA/HyQvia in CIDP

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Spain, Canada, Poland, Italy, Serbia, Germany, Mexico, Turkey, United Kingdom, Czechia, France, United States, Argentina, Brazil, Colombia, Denmark, Greece, Slovakia
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
Andromeda Biotech Ltd.

Completed

Efficacy Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Patients (DIA-AID)

Type 1 Diabetes

France, Italy, United Kingdom, Israel, South Africa, Spain, Austria, Czech Republic, Finland, Germany, Greece

Clinical Trials on Active Immune Response in Czechia

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