Clinical Trials on Acute Coagulopathy

Total 15421 results

Monash University
National Health and Medical Research Council, Australia; Health Research Council...

Completed

Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study) (PATCH)

Wounds and Injuries | Acute Coagulopathy

Australia, New Zealand
Zdravotnicka Zachranna Sluzba Kralovehradeckeho...
University Hospital Hradec Kralove

Unknown

Rapid Administration of Blood by HEMS in Trauma (RABBIT)

Wounds and Injuries | Trauma | Acute Coagulopathy

Czechia
Denver Health and Hospital Authority
Haemonetics Corporation

Completed

Comparison of Rapid Thrombelastography and Conventional Coagulation Testing for Haemostatic Resuscitation in Trauma

Acute Coagulopathy

United States
CSL Behring

Completed

Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects

Acute Major Bleeding | Reversal of Coagulopathy

Japan
First Affiliated Hospital of Harbin Medical University

Unknown

Role of Microparticles in the Coagulopathy of Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia

China
Karolinska University Hospital

Recruiting

Transfusion for Major Haemorrhage in Trauma - Characteristics and Outcomes

Hemorrhage | Trauma | Shock, Traumatic | Acute Coagulopathy

Sweden
University of Zurich

Completed

Hemodilution and Coagulopathy With 3 Colloids

Dilutional Coagulopathy

Switzerland
Emory University

Withdrawn

An Observational Study of Early Coagulopathy, or Clotting Disorder, in Injured Patients

Trauma-induced Coagulopathy

United States
Mahidol University

Completed

Coagulopathy in Cardiac Surgery

Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

Thailand
University of Rochester

Completed

Evaluating URMC's Massive Transfusion Protocol (MTP-TEG)

Blood Coagulation Disorders | Trauma | Acute Coagulopathy

United States
Goethe University

Unknown

Point-of-Care Testing in Coagulopathic Patients Undergoing Cardiac Surgery - a Multicenter Study (MultiPOC)

Coagulopathy During Cardiac Surgery

Germany, Austria
CSL Behring

Completed

An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical Procedure (BE1116_3003)

Reversal of Coagulopathy

United States, Belarus, Bulgaria, Lebanon, Romania, Russian Federation
Johns Hopkins University

Terminated

The Utility of Thromboelastography in Cirrhotic Patients Undergoing Endoscopic Procedures

Cirrhosis, Coagulopathy
The Hospital for Sick Children
Synapse B.V. Research Institute, University of Maastricht

Unknown

Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass

Platelet Function Tests | Thrombin Generation Tests | Perioperative Coagulopathy

Canada
Petra Hartmann MD Ph.D.

Not yet recruiting

Mitochondrial Dysfunction in Trauma-related Coagulopathy

Trauma Induced Coagulopathy

Hungary
Medical University of Silesia

Active, not recruiting

Impact of Balanced Crystalloid and Colloid Infusion on Haemostasis in Healthy Male Volunteers

Perioperative Hemorrhage | Dilutional Coagulopathy

Poland
National University Hospital, Singapore

Completed

Efficacy and Safety of Heparin-grafted Membrane for CRRT (CARROM)

Hemorrhage | Acute Kidney Injury | Coagulopathy

Singapore
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Direction Centrale du Service de Santé des Armées
Floralis; TIMC-IMAG

Recruiting

Evaluation of a Transfusion Therapy Using Whole Blood in the Management of Coagulopathy in Patients With Acute Traumatic Hemorrhage (T-STORHM)

Trauma | Coagulopathy | Acute Hemorrhage

France
Asahi Kasei Pharma America Corporation

Withdrawn

The Safety And Efficacy of ART-123 in Subjects With Sepsis and Coagulopathy (Scarlet2)

Sepsis and Coagulopathy
University of Edinburgh
CSL Behring; NHS Lothian

Completed

Fibrinogen as an Alternative to FFP in Aortic Surgery.

Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair

United Kingdom
Xu Li
LanZhou University; The Affiliated Nanjing Drum Tower Hospital of Nanjing University... and other collaborators

Not yet recruiting

Nafamostat Mesilate in the Treatment of Severe Infection-associated Coagulopathy (NMSICRCT)

Sepsis | Sepsis-induced Coagulopathy | Nafamostat Mesilate
Sunnybrook Health Sciences Centre
Canadian Blood Services; National Blood Foundation; Canadian Department of National...

Completed

The Trauma- Formula-Driven Versus Lab-Guided Study (TRFL Study) (TRFL)

Hemorrhagic Shock | Trauma Coagulopathy

Canada
Duke University
CSL Behring

Completed

Open Label Use Of RiaStap During Aortic Reconstruction

Coagulopathic Bleeding

United States
Velico Medical

Enrolling by invitation

Ascending Dose Study of FrontlineODP™ Spray Dried Plasma

Hemorrhage | Coagulopathy

United States
Jubilee Mission Medical College and Research Institute

Completed

Hemostatic Variables In Snakebite Study (HISS)

Snake Bites | Coagulopathy, Consumption

India
University of Utah

Recruiting

Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence

Anemia | Thrombocytopenia | Coagulopathy, Mild | Hypofibrinogenemia

United States
HealthPartners Institute

Completed

Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal (kcentra)

Hemorrhage | Acute Bleeding on Long-Term Anticoagulation Therapy | Significant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time) | Urgent Reversal of Vitamin K Antagonist (VKA) Anticoagulation

United States
Sion Microtec Ltd.

Unknown

Safety and Efficacy Study Comparing Pad-gauze With Anti-fibrinolytic Agent Hemostopan™) to a Regular Pad-gauze

Bleeding | Coagulopathy

Israel
Samsung Medical Center

Unknown

Edoxaban for the Treatment of Coagulopathy in Patients With Active Cancer and Acute Ischemic Stroke: a Pilot Study. (ENCHASE Study) (ENCHASE)

Correction of Cancer-related Coagulopathy With Novel Oral Anticoagulant (Edoxaban)

Korea, Republic of
The Third Xiangya Hospital of Central South University
Hunan Cancer Hospital; Hunan Provincial People's Hospital; Second Xiangya Hospital... and other collaborators

Completed

Thromboelastography Normal Reference Values in China Hunan Province

Coagulopathy | Blood Transfusion Complication

China
Octapharma

Completed

Octaplas Pediatric Plasma Replacement Trial

Cardiac Surgery | Liver Dysfunction | Coagulopathy | Liver Surgery

United States
Brno University Hospital

Recruiting

Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery (EFISS)

Bleeding | Spine Deformity | Coagulopathy, Consumption | Fibrinogen

Czechia
Gold Coast Hospital and Health Service
Emergency Medicine Foundation; National Blood Authority; Australian Red Cross

Unknown

Fibrinogen Early In Severe Trauma studY Junior (FEISTY Jnr)

Hemorrhage | Trauma | Coagulopathy | Pediatrics

Australia
Assiut University

Unknown

Coagulation Parameters in IBD Patients

Coagulopathy
Gold Coast Hospital and Health Service
Emergency Medicine Foundation; National Blood Authority; Australian Red Cross

Completed

Fibrinogen Early In Severe Trauma studY (FEISTY)

Trauma | Coagulopathy | Haemorrhage

Australia
Indiana University

Recruiting

Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients

Coagulopathy

United States
Entegrion, Inc.

Terminated

Comparison of the Efficacy & Safety of Resusix With FP24 in Patients With Acquired Coagulopathy

Coagulopathy

United States
Weill Medical College of Cornell University

Terminated

Trial of RiaSTAP Versus Cryoprecipitate to Lower Operative Transfusions (TOP-CLOT)

Coagulopathy

United States
Stanford University

Completed

Quantra vs TEG for Congenital Cardiac Surgery - a Pilot Validation Study

Coagulopathy

United States
University Hospital, Motol

Completed

ROTEM Assessment of Modern Crystalloid, Hydroxyethyl Starch and Gelatin Effect on Coagulation

Coagulopathy

Czechia
Rambam Health Care Campus

Unknown

Quantification of Thrombocytes Number and Function in Patients Undergoing Prolonged Extracorporeal Circulation (CPB-PLT-FNCT)

Coagulopathy
HaEmek Medical Center, Israel

Completed

The Correlation Between The New Sepsis Scores - SOFA, Quick SOFA and Calibrated Automated Thrombogram Values

Sepsis | Coagulopathy

Israel
University of Iowa

Completed

Covid-19 Associated Coagulopathy

COVID 19 Associated Coagulopathy

United States
Cambridge University Hospitals NHS Foundation Trust
HemoSonics LLC

Withdrawn

Clinical Evaluation of the Hemosonics Quantra® Coagulation Monitor in Liver and Multivisceral Transplantation

Liver Transplantation | Coagulopathy
Australian and New Zealand Intensive Care Research...
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian... and other collaborators

Recruiting

Fibrinogen Early In Severe Trauma StudY II (FEISTY II)

Trauma | Coagulopathy | Haemorrhagic Shock

Australia
Hospital Clinic of Barcelona

Unknown

Thromboelastometry in Liver Transplantation

Liver Transplant Disorder | Coagulopathy

Spain
The University of Texas Health Science Center,...
Haemonetics Corporation

Completed

A Prospective Evaluation of Thromboelastography for Identifying Coagulopathy in Severely Injured Patients (RapidTEG)

Coagulopathy

United States
University Hospital, Montpellier

Not yet recruiting

Evaluation of TEG 6S PM® During Cardiopulmonary Bypass to Detect Postoperative Biological Coagulopathy (PREDIPOC)

Cardiac Surgery | Cardiopulmonary Bypass | Coagulopathy

France
Medstar Health Research Institute
United States Department of Defense

Completed

Chronology of Occult and Gross Coagulopathy in Burn Patients

Thermal Burns

United States

Clinical Trials on Acute Coagulopathy

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