Clinical Trials on Acute Gout Flare

Total 16448 results

Uppsala University

Unknown

Lactobacillus Reuteri ATCC PTA 4659 in Ulcerative Colitis (COLUS)

Ulcerative Colitis Flare

Sweden
Centre Hospitalier Saint Joseph Saint Luc de Lyon

Recruiting

NLRP3 Inflammasome Activation Among Patients During Acute Gout Flares (ActiNG)

Gout Arthritis

France
Swedish Orphan Biovitrum

Completed

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy (DISSOLVE I)

Chronic Gout

United States
Swedish Orphan Biovitrum

Completed

A Study of SEL-212 in Patients With Gout Refractory to Conventional Therapy II (DISSOLVE II)

Chronic Gout

United States, Serbia, Georgia, Ukraine, Russian Federation
RenJi Hospital
Westlake Therapeutics

Not yet recruiting

A Exploratory Trial of WTX221 in Refractory Gout Patients

Gout Tophus
Regeneron Pharmaceuticals

Completed

PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1 (PRE-SURGE1)

Intercritical Gout

United States, Canada
Peking University Third Hospital

Recruiting

The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study (INITIAL)

Gout

China
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Active, not recruiting

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs Allopurinol

Gout

United States
Lille Catholic University
Horizon Pharma Rheumatology LLC

Completed

Study of the Correlation Between UltraSonography and Dual-Energy Computed Tomography Assessment of Urate Deposit (GOUT)

Gout

France
Meander Medical Center

Unknown

Diagnostic Value of DECT Scan Compared to Diagnostic Needle Aspiration (DEteCT)

Gout

Netherlands
Selecta Biosciences, Inc.

Completed

Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levels

Gout

United States
Ardea Biosciences, Inc.

Completed

RDEA3170 PK/PD Study

Gout

United States
Ardea Biosciences, Inc.

Completed

NSAID Drug Interaction Study

Gout

United States
University of California, Los Angeles

Enrolling by invitation

Recapturing Immune Tolerance to Pegloticase for the Management of Tophaceous Gout

Tophaceous Gout

United States
Horizon Therapeutics Ireland DAC

Completed

Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy

Uncontrolled Gout

United States
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol

Intercritical Gout

United States
Takeda

Completed

Drug Use Study of Febuxostat After Recent Changes in the Prescribing Information

Cardiovascular Diseases | Gout

United States
Arthrosi Therapeutics

Completed

Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients

Gout Patients

New Zealand
Rutgers, The State University of New Jersey
Amgen

Terminated

Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gout

Gout Attack

United States
Horizon Therapeutics Ireland DAC

Completed

Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant

Uncontrolled Gout | Kidney Transplant

United States
Selecta Biosciences, Inc.

Completed

A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy (COMPARE)

Chronic Gout

United States
University of Patras

Unknown

ACTH vs Betamethasone in Hospitalized Patients With Acute Gout

Gout Attack

Greece
Arthritis & Rheumatism Associates, P.C.

Completed

Elastography as Gouty Arthropathy Outcome (EGO)

Gout

United States
University of Mississippi Medical Center

Terminated

The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot Study

Blood Pressure | Gout

United States
Ampel BioSolutions, LLC
IND 2 Results LLC

Completed

Tolerization Reduces Intolerance to Pegloticase and Prolongs the Urate Lowering Effect (TRIPLE)

Gout

United States
Brigham and Women's Hospital
Biofourmis Inc.

Active, not recruiting

Prediction of Patient Deterioration Using Machine Learning

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Brigham and Women's Hospital
RxFoundation

Completed

Rural Home Hospital: Proof of Concept

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Brigham and Women's Hospital
Biofourmis Inc.

Active, not recruiting

Prediction of Expected Length of Hospital Stay Using Machine Learning

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
Sunshine Lake Pharma Co., Ltd.

Recruiting

A Clinical Trial of HEC93077 in Chinese Healthy Subjects and HUA Patients With Single or Multiple Dosing

Gout

China
University of Alabama at Birmingham
University of Michigan

Completed

REduCing Immunogenicity to PegloticasE (RECIPE) Study (RECIPE)

Gout Chronic

United States
Shanton Pharma Co., Ltd.

Completed

Placebo Controlled, Dose Escalation Study to Evaluate Safety, Pharmacokinetics & Efficacy of SAP-001 in Gout Patients

Gout, Hyperuricemia

United States
USDA, Western Human Nutrition Research Center

Active, not recruiting

Yogurt and GI Health

Gut Microbiome | Gut Health | Yogurt Intake | Gastrointestinal Immune Function

United States
Brigham and Women's Hospital
Biofourmis Inc.

Not yet recruiting

Prediction of 30-Day Readmission Using Machine Learning

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Brigham and Women's Hospital

Completed

Remote Physician Care for Home Hospital Patients

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Jiangsu Atom Bioscience and Pharmaceutical Co.,...

Completed

Study to Investigate the Effects of Food on Relative Bioavailability of ABP-671 Tablets in Healthy Subjects

Gout | Food-drug Interaction

United States
DePuy International

Completed

Postmarketing Study to Determine Performance of the SIGMA HP® PARTIAL KNEE SYSTEM

Osteoarthritis | Post-traumatic Arthritis | Gout | Pseudo-gout

Switzerland, Italy
Savient Pharmaceuticals

Completed

Re-exposure Study of Pegloticase Intravenous (i.v.) in Symptomatic Gout Patients

Chronic Gout Refractory to Conventional Therapy

United States
University of California, Davis

Completed

The Influence of Oral Probiotics on the Microbiome and Lipidome

Gut Microbiome | Skin Microbiome | Gut Lipidome | Skin Lipidome | Blood Lipidome

United States
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Gout With Hyperuricemia in Adults
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults

Gout With Hyperuricemia in Adults
Fuji Yakuhin Co., Ltd.
Mochida Pharmaceutical Company, Ltd.

Completed

Benzbromarone-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia With or Without Gout

Japan
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Study of FYU-981 in Hyperuricemic Outpatients With or Without Gout (Effect on Two Hyperuricemic Types)

Hyperuricemia With or Without Gout

Japan
AstraZeneca
Ardea Biosciences, Inc.

Completed

Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic Hyperuricemia

Gout and Hyperuricemia

Japan
SK Chemicals Co., Ltd.

Completed

Clinical Study to Evaluate the Pharmacokinetic Characteristics Between TMX-67 and Feburic® in Healthy Volunteers

Gout

Korea, Republic of
Horizon Pharma Rheumatology LLC

Completed

Observational Study of the Use of Pegloticase (KRYSTEXXA®) in Refractory Chronic Gout (EyesOnGOUT)

Refractory Chronic Gout

United States
Liverpool John Moores University
University of Illinois at Chicago; Georgia Southern University

Completed

Effect of Probiotics on Endurance Athletes' Microbiome at Rest and Post-race

Probiotics | Athletes | Gut Microbiota | Aerobic Exercise | Gut Microbiome | Gastrointestinal Tract Irritation

United Kingdom
Selecta Biosciences, Inc.

Completed

Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid

Hyperuricemia | Gout Chronic

United States
Fuji Yakuhin Co., Ltd.
Mochida Pharmaceutical Company, Ltd.

Completed

Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia With or Without Gout

Japan
Mochida Pharmaceutical Company, Ltd.
Fuji Yakuhin Co., Ltd.

Completed

Febuxostat-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

Hyperuricemia With or Without Gout

Japan

Clinical Trials on Acute Gout Flare

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