Clinical Trials on Adenoviridae Infections in United States

Total 20186 results

AlloVir
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Completed

ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK Virus (ARMS)

Viral Infection

United States
AlloVir
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Withdrawn

Most Closely Human Leukocyte Antigen (HLA)-Matched Adenovirus-specific T Lymphocytes (Viralym-A)

Adenovirus Infection

United States
Emergent BioSolutions
Walter Reed Army Institute of Research (WRAIR)

Terminated

A Study to Assess the Safety, Pharmacodynamics, and Immunogenicity of PXVX0047

Adenoviral Infection

United States
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI); The Methodist Hospital Research... and other collaborators

Completed

Administration of Virus-Specific Cytotoxic T-Lymphocytes (LYPTAIST)

Adenovirus Infection

United States
Mari Dallas

Recruiting

Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Nationwide Children's Hospital

Recruiting

Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections (ADV-VSTS)

Adenovirus Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute

Recruiting

TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT. (TETRAVI)

Viral Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus (ACT-CAT)

Cytomegalovirus Infection | Adenovirus Infection

United States
Cell Medica Ltd
Technology Strategy Board, United Kingdom

Completed

Safety Study of ADV-specific T-cells in Paediatric Patients Post Allo-HSCT (ASPIRE)

ADV Infection Post Allo-HSCT

United Kingdom
SymBio Pharmaceuticals

Recruiting

A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection (ATHENA)

Adenovirus Infection

United States
Children's National Research Institute
M.D. Anderson Cancer Center

Completed

Cytotoxic T Cells to Prevent Virus Infections

CMV | EBV | Adenovirus Infections

United States
Chimerix

Completed

Study to Assess the Safety and Efficacy of Brincidofovir in Treatment of Early Versus Late Adenovirus Infection

Adenovirus Infection

United States
Baylor College of Medicine
Duke University; University of Texas Southwestern Medical Center; Children's... and other collaborators

No longer available

Allogeneic Virus-Specific Cytotoxic T-Lymphocytes(CTL), Persistent/Recurrent Viral Infection Post-HSCT (EAP CHALLAH) (EAP CHALLAH)

Adenoviral Infection | CMV Infection | EBV Infection

United States
Teva Branded Pharmaceutical Products R&D, Inc.
United States Department of Defense

Withdrawn

Adenovirus Vaccine Pregnancy Registry

Adenovirus

United States
Catherine Bollard

Active, not recruiting

Allogeneic Multivirus - Directed Cytotoxic T Lymphocytes (CTL)

CMV | EBV | Adenovirus

United States
St. Jude Children's Research Hospital

Recruiting

Haplo-identical Viral-Specific T-cells for Treatment of Cytomegalovirus and Adenovirus Infections After Hematopoietic Cell Transplantation

Cytomegalovirus | Adenovirus

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)

Epstein-Barr Virus Infections | Stem Cell Transplant | Cytomegalovirus Infections | Adenovirus Infection

United States
AlloVir

Terminated

Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation

Adenovirus Infection

United States, Spain, United Kingdom, Italy, Canada, Sweden
Medical College of Wisconsin

Completed

Using Multi-virus Cytotoxic T-cells Following T-Cell Depleted Allogeneic HPCT for Prophylaxis Against EBV, ADV, and CMV (ACE)

Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus

United States
Baylor College of Medicine
M.D. Anderson Cancer Center; Massachusetts General Hospital; National Heart,... and other collaborators

Completed

Most Closely HLA Matched Allogeneic Virus Specific Cytotoxic T-Lymphocytes (CTL) (CHALLAH)

EBV Infection | Adenovirus Infection

United States
Jessie L. Alexander

Active, not recruiting

Viral Specific T-Lymphocytes to Treat Adenovirus, CMV and EBV

Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus

United States
Chimerix

Terminated

The AdAPT Trial; Adenovirus After Allogeneic Pediatric Transplantation (AdAPT)

Adenovirus

United States, Spain, France, Italy, United Kingdom, Netherlands, Germany, Ireland, Poland
Chimerix

Terminated

A Multicenter Study to Obtain Retrospective Data for Subjects Previously Diagnosed With Adenovirus Infection to Serve as Matched Historical Controls for Study CMX001-304

Adenovirus

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

Hematopoietic and Lymphoid Cell Neoplasm | Immunocompromised

United States
Altimmune, Inc.

Completed

Safety and Immunogenicity Study of Adenovirus-vectored, Intranasal Pandemic Influenza Vaccine.

Influenza A Subtype H5N1 Infection

United States
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Expanded Characterization of Immune Response to Merck Adenovirus 5 Gag/Pol/Nef Vaccine Given to HIV Uninfected Adults

HIV Infections

United States
Chimerix

No longer available

Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease

Adenovirus

United States
Steven B. Kleiboeker
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Adenovirus and Fungal Load in Pediatric Stem Cell Transplant Patients

Adenovirus | Other Mycoses

United States
Chimerix

Completed

Phase 2 Study to Evaluate Brincidofovir for the Prevention of Adenovirus Disease

Adenovirus Disease

United States
Arisan Therapeutics, Inc.
United States Department of Defense; Battelle Memorial Institute; The Defense...

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral ARN-75039 in Healthy Adult Subjects

Lassa Virus Infection

United States
National Institute of Allergy and Infectious Diseases...
Gritstone bio, Inc.

Completed

Chimpanzee Adenovirus and Self-Amplifying mRNA Prime-Boost Prophylactic Vaccines Against SARS-CoV-2 in Healthy Adults

COVID-19

United States
Sumithira Vasu

Recruiting

Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT

Cytomegalovirus | Adenovirus | Donor | Allogeneic Hematopoietic Stem Cell Transplantation Recipient | Solid Organ Transplantation Recipient

United States
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Immunogenicity of the Ebola Chimpanzee Adenovirus Vector Vaccine (cAd3-EBO), VRC-EBOADC069-00-VP, in Healthy Adults

Healthy Adult Immune Responses to Vaccine

United States
Chimerix

Withdrawn

Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia

Adenovirus

United States, Spain, Italy
International AIDS Vaccine Initiative
Brigham and Women's Hospital; George Washington University; Redemption Hospital; East-West Medical Research Institute

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults in Good General Heath

Lassa Fever | Lassa Virus Infection

United States, Liberia
Lifelong Vision Foundation
Bausch & Lomb Incorporated

Completed

A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis

Keratoconjunctivitis Due to Adenovirus | Viral Shedding

United States
GenMark Diagnostics

Completed

Residual Sample Collection for Respiratory Viral Panel

Respiratory Viral Illnesses: Influenza A/B, RSV, Adenovirus

United States
AlloVir

Active, not recruiting

Posoleucel (ALVR105, Formerly Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (Prevent)

BK Virus Infection | Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus Infection | JC Virus Infection | Human Herpes Virus-6 Infection

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | BK Virus Infection | Symptomatic COVID-19 Infection Laboratory-Confirmed | Adenovirus Infection | Cytomegaloviral Infection | JC Virus Infection

United States
AlloVir

Terminated

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (Prevent)

BK Virus Infection | Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus Infection | JC Virus Infection | Human Herpes Virus-6 Infection

Korea, Republic of, United States, Spain, France, Turkey, Australia, United Kingdom, Italy, Canada, Belgium
Michael Pulsipher, MD

Active, not recruiting

Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES)

Cytomegalovirus Infections | EBV Infection | Adenovirus Infection

United States
Inovio Pharmaceuticals
Coalition for Epidemic Preparedness Innovations

Completed

Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers

Lassa Fever

United States
Bernhard Nocht Institute for Tropical Medicine
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Completed

Pharmacokinetics, Tolerability and Safety of Favipiravir Compared to Ribavirin for the Treatment of Lassa Fever (SAFARI)

Lassa Fever

Nigeria
New York Medical College
Johns Hopkins University; University of Colorado, Denver; Children's Hospital... and other collaborators

Recruiting

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

Primary Immune Deficiency Disorder | Adenovirus

United States
University of Oxford

Completed

Cardiovascular Function and Ribavirin PK/PD in Lassa Fever in Lassa Fever

Lassa Fever

Nigeria
Benjamin Movsas, M.D.

Withdrawn

Oncolytic Adenovirus-Mediated Gene Therapy for Lung Cancer (NSCLC)

Non-small Cell Lung Cancer Stage I

United States
Mayo Clinic
Ortho-McNeil, Inc.

Completed

The Utility of Levofloxacin-Rifampin in the Therapy of Prosthetic Joint Infection

Staphylococcal Infection | Staphylococcus Aureus Prosthetic Joint Infection

United States
Orlando Health, Inc.
Forest Laboratories

Withdrawn

Ceftaroline in the Treatment of Bone and Joint Infections

Osteomyelitis | Joint Infections

United States
QIAGEN Gaithersburg, Inc

Completed

Collection and Testing of Respiratory Samples

Respiratory Syncytial Virus Infections | Influenza A | Rhinovirus | Influenza B | QIAGEN ResPlex II Advanced Panel | Infection Due to Human Parainfluenza Virus 1 | Parainfluenza Type 2 | Parainfluenza Type 3 | Parainfluenza Type 4 | Human Metapneumovirus A/B | Coxsackie Virus/Echovirus | Adenovirus Types B/C/E | Coronavirus Subtypes 229E and other conditions

United States
Aaron Chen
Johns Hopkins University; Thrasher Research Fund

Completed

Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections

Staphylococcal Skin Infection | Abscess | Staphylococcal Infection | Folliculitis

United States

Clinical Trials on Adenoviridae Infections in United States

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