Clinical Trials on Adult Brain Stem Glioma

Total 1248 results

Ivy Brain Tumor Center
GlaxoSmithKline

Not yet recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Glioblastoma | Brain Tumor | GBM | Brain Neoplasms, Adult, Malignant
Center Eugene Marquis

Completed

Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors (GLIROPA)

Brain Neoplasms | Adult Brain Tumor

France
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Roswell Park Cancer Institute; American Lebanese...

Recruiting

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Glioblastoma Multiforme | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | High-grade Astrocytoma NOS

United States, Canada
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy

Lung Cancer | Radiation Toxicity | Adult Brain Tumor

United States
City of Hope Medical Center

Active, not recruiting

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Solid Tumor | Ewing Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Adult Brain Tumor | Recurrent... and other conditions

United States
Tilburg University

Completed

Effects of Exercise on Cognitive Function in Glioma Patients

Low Grade Glioma of Brain | Anaplastic Glioma of Brain

Netherlands
National Cancer Institute (NCI)

Completed

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Soft Tissue Sarcoma | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma | Childhood Central Nervous System Germ Cell Tumor | Childhood Central Nervous System Choriocarcinoma | Childhood Central... and other conditions

United States
Milton S. Hershey Medical Center
National Cancer Institute (NCI)

Recruiting

Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trial

Glioblastoma | Glioblastoma Multiforme | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain

United States
Washington University School of Medicine

Recruiting

Temporally-modulated Pulsed Radiation Therapy (TMPRT) After Prior EBRT for Recurrent IDH-mutant Gliomas

Astrocytoma | Glioma, Malignant | Oligodendroglioma, Adult

United States
Children's Hospital of Philadelphia
Blue Earth Diagnostics; Dragon Master Foundation

Not yet recruiting

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

Glioma | Low-grade Glioma | Glioma, Malignant | Low Grade Glioma of Brain | Glioma Intracranial

United States
Milton S. Hershey Medical Center

Recruiting

Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas

Glioblastoma | Glioblastoma Multiforme | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain

United States
Emory University

Completed

Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Recurrent Brain Tumor | Mixed Gliomas
Assistance Publique - Hôpitaux de Paris

Completed

Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem Cells (MSC)

SYSTEMIC SCLERODERMA | ALLOGENEIC MESENCHYMAL STEM CELLS | ADULT

France
National Cancer Institute (NCI)

Completed

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

Brain Tumors | High Grade Gliomas

United States
National Cancer Institute (NCI)

Completed

MRI and PET/FMISO In Assessing Tumor Hypoxia in Patients With Newly Diagnosed Glioblastoma Multiforme

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Atypical Teratoid/Rhabdoid Tumor | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Recurrent Childhood... and other conditions

United States
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
Oliver Jonas, PhD

Recruiting

Implantable Microdevice In Primary Brain Tumors

Glioblastoma | Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Astrocytoma of Brain | Grade III Glioma | Grade IV Glioma | Grade II Glioma | Oligodendroglioma of Brain

United States
Vigil Neuroscience, Inc.

Recruiting

Natural History Study in Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia (ALSP)

ALSP

United States, Canada, Germany, Netherlands, United Kingdom
Vigil Neuroscience, Inc.

Active, not recruiting

A Study of VGL101 in Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia

ALSP

United States, France, Germany, Netherlands, United Kingdom
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

Glioma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Central Nervous System Neoplasms | Brain Tumor | High Grade Glioma | Glioma, Malignant | Neoplasm Malignant | Photosensitizing Agents | Tumour, Residual | Brain Neoplasms, Adult, Malignant

Ecuador
National Cancer Institute (NCI)

Recruiting

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Lynch Syndrome | Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Refractory Ependymoma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Refractory Diffuse Intrinsic Pontine Glioma | Recurrent Brain Neoplasm | Refractory Brain Neoplasm | Constitutional...

United States, Canada
Neurological Associates of West Los Angeles

Enrolling by invitation

The Use of Focused Ultrasound and DCE K-trans Imaging to Evaluate Permeability of the Blood-Brain Barrier

Low Grade Glioma of Brain

United States
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Neuroblastoma | Pediatric Cancer | Diffuse Intrinsic Pontine Glioma | Pediatric Brain Tumor | Refractory Cancer | Refractory Neoplasm | Refractory Tumor | Cancer Pediatric | Neuroblastoma Recurrent | Pediatric Lymphoma | Pediatric Meningioma

United States
Incyte Corporation

Active, not recruiting

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

Glioblastoma | Adult-type Diffuse Gliomas

United States, Spain, Italy, United Kingdom, Germany, Japan, France, Netherlands, Denmark
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
National Institute of Neurological Disorders and...

Recruiting

Study of New Magnetic Resonance Imaging Methods of the Brain

Healthy | Magnetic Resonance Imaging | Healthy Volunteer | Adult | fMRI | Brain Mapping

United States
Icahn School of Medicine at Mount Sinai

Completed

The Effects of Ondansetron on Brain Function

Healthy Adults | Brain Function

United States
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202) (RESBIOP)

Glioblastoma | Glioblastoma Multiforme | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Glioblastoma Multiforme of Brain

United States, Belgium, Switzerland, Germany, Netherlands
Beijing Tiantan Hospital

Recruiting

Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials

Brain Tumor Adult

China
University of Rochester
Schmitt Program on Integrative Neuroscience

Recruiting

A Study of Cognitive Changes in Patients Receiving Brain Radiation

Brain Tumor Adult

United States
University of Utah

Recruiting

Safety and Feasibility of Preoperative and Intraoperative Image-Guided Resection of Gliomas

Brain Tumor Adult

United States
sohaila Essam

Unknown

Role of Fibirnogen Like Protein 2 as Aprognostic Factor in High Grade Glioma

Brain Tumor Adult
National Cancer Institute (NCI)

Completed

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Brain Stem Glioma | Childhood Spinal Cord Neoplasm | Childhood Cerebral Anaplastic Astrocytoma | Cerebral Astrocytoma | Childhood Cerebellar Anaplastic Astrocytoma

United States, Canada
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial

Meningioma | Low Grade Glioma | Malignant Brain Neoplasm | Malignant Brain Glioma

United States
Colombian Foundation for Epilepsy and Neurological...

Unknown

Efficacy of Tranexamic Acid in Brain Tumor Resections (COLFIRE)

Neoplasms | Brain Tumors | Gliomas | Astrocytomas | Meningiomas

Colombia
Annick Desjardins
Amgen

Terminated

Panitumumab and Irinotecan for Malignant Gliomas

Malignant Glioma of Brain

United States
Seattle Children's Hospital

Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Glioma | Ependymoma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Central Nervous System Tumor | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Pineoblastoma, Childhood

United States
M.D. Anderson Cancer Center

Withdrawn

Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR

Cancer | Glioblastoma | Brain Metastases | Gliomas

United States
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Recurrent Meningioma

Recurrent Adult Brain Tumor | Adult Grade I Meningioma | Adult Grade II Meningioma | Adult Meningeal Hemangiopericytoma | Adult Meningioma | Adult Grade III Meningioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Glioblastoma | Gliosarcoma | Ependymoma | Anaplastic Astrocytoma | Oligodendroglioma | Anaplastic Ependymoma | Giant Cell Glioblastoma | Astrocytoma, Grade II | Brainstem Tumors

United States
Children's Hospital Los Angeles
Dana-Farber Cancer Institute

Active, not recruiting

Study of MEK162 for Children With Low-Grade Gliomas

Soft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, Brain

United States
Wise S.r.l.
Fondazione Don Carlo Gnocchi Onlus; Genae

Completed

WISE Cortical Strip for Intraoperative Neurophysiological Monitoring (WIN)

Epilepsy | Brain Tumor Adult

Switzerland, Germany, Italy
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
Beijing Sanbo Brain Hospital

Recruiting

Modified CV Regimen in Optic Pathway Glioma

Optic Glioma | Pediatric Brain Tumor, Optic Nerve Glioma

China
Duke University
Monteris Medical

Withdrawn

LITT Palliative Treatment for Patients With Malignant Gliomas

Glioblastoma | Malignant Glioma of Brain

United States
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
Northwell Health

Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
UMC Utrecht

Recruiting

The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA) (COIMBRA)

Brain Metastases, Adult | Brain Neoplasms, Adult, Malignant

Netherlands

Clinical Trials on Adult Brain Stem Glioma

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