Clinical Trials on Adult Healthy Volunteers

Total 23955 results

University of Pennsylvania
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Glucose Counterregulation in Long Standing Type 1 Diabetes

Healthy | Type 1 Diabetes | Hypoglycemia Unawareness

United States
Bristol-Myers Squibb

Terminated

BMS-986325 in Healthy Participants and Participants With Primary Sjögren's Syndrome

Healthy Participants | Primary Sjögren's Syndrome

Germany, United States
University of Nottingham

Active, not recruiting

Phenotyping of Adult Crohn's Focusing on Sarcopenia (PACS)

Inflammatory Bowel Diseases | Sarcopenia | Crohn Disease | Digestive System Disease | Nutrition, Healthy | Protein Malabsorption

United Kingdom
Novo Nordisk A/S

Terminated

A Multi-centre, Open Labelled, Multiple Dosing Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC 0172-2021 Administered Subcutaneously to Healthy Male Subjects and Haemophilia Subjects (explorer™2)

Healthy | Congenital Bleeding Disorder | Haemophilia A

Austria, Spain, United Kingdom, France, Germany
Biogen

Completed

A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's Syndrome

Healthy | Sjögren's Syndrome | Sicca Syndrome

United States
GlaxoSmithKline

Completed

Drug Interaction Study of Darunavir/Ritonavir and Lopinavir/Ritonavir on GSK2248761 PK and CYP450 Probe Drugs

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Hormone Replacement in Young Women With Premature Ovarian Failure

Healthy | Osteoporosis | Premature Ovarian Failure

United States
Dana-Farber Cancer Institute

Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions

United States
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Johns Hopkins University and other collaborators

Not yet recruiting

IGHID 12219 - A Brief Alcohol Intervention for PrEP Use Among MSM in Vietnam (BPrEP)

HIV Prevention | Unhealthy Alcohol Use

Vietnam
University Hospital Goettingen
German Research Foundation

Recruiting

Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients (DOUBLE_PROTECT)

Chronic Kidney Failure in Children and Young Adults

Germany
Navy General Hospital, Beijing

Not yet recruiting

Smart Technology Facilitated Patient-centered Care for Patients With Pulmonary Thromboembolism (SmaPE)

Venous Thromboembolism | Clinical Decision Support Systems | Digital Health | Pulmonary Thromboembolisms

China
Center for Primary Care and Public Health (Unisante)...
University of Lausanne Hospitals; Neuchâtel Psychiatry Centre (CNP)

Not yet recruiting

Psychiatric Consultation-Liaison Intervention in Primary Care: A Pilot Study (PLIMeC-P)

Quality of Life | Mental Health Issue | Collaboration | Psychosomatic Disorders | Doctor-Patient Relation | Depression/Anxiety | Patients Lived Experiences

Switzerland
Shenzhen Hospital of Southern Medical University

Not yet recruiting

Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults

Irritable Bowel Syndrome With Diarrhea | Mental Health Issue | Fecal Microbiota Transplantation

China
Vejle Hospital
Region of Southern Denmark

Recruiting

Impact of COPD on Sexual Health, Loneliness, and Well-being

Pulmonary Disease, Chronic Obstructive | Loneliness | Sexual Health | Well-Being, Psychological

Denmark
Portland State University
National Institute of Mental Health (NIMH)

Recruiting

Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care

Depression | Stress Disorders, Post-Traumatic | Anxiety | Coping Behavior | Emotion Regulation | Adolescent Behavior | Psychosocial Functioning | Help-Seeking Behavior | Child Welfare | Utilization, Health Care

United States
University of Zagreb

Not yet recruiting

Salivary Minerals in Patients With Peri-implantitis (mineral-perio)

Peri-implant Mucositis | Peri-Implantitis and Peri-implant Mucositis | Peri-implant Health | Periimplant Diseases | Periimplant Bone Loss
Frank Wieber

Not yet recruiting

HRQoL in Overweight and Obese Children/Adolescents

Obesity, Childhood | Obesity, Adolescent | Overweight and Obesity | Health Related Quality of Life | Intervention Program
Assiut University

Recruiting

Short and Long-term Psychological Impact of Covid-19 on The Egyptians

Mental Health Issue

Egypt
Duke University
Public Health Research Institute of India

Completed

Feasibility of Kanasina Gulabi, a Pilot Peer Support Intervention for Young Adults With Type 2 Diabetes in Mysore District, South India

Depression | Quality of Life | Type 2 Diabetes | Behavior, Health | Stigma, Social

India
Montefiore Medical Center

Completed

Implementing, a Mobile Health Application for HIV Infected and Uninfected Women With Co-morbidities in the Outpatient Setting

Diabetes Mellitus | Asthma | Mobile Health

United States
Harvard Medical School (HMS and HSDM)
Partners in Health

Active, not recruiting

Leveraging Community Health Workers to Combat COVID-19 and Mental Health Misinformation in Haiti, Malawi, and Rwanda

COVID-19 | Mental Health | Misinformation

Haiti, Malawi, Rwanda
Marmara University

Completed

Health Belief Model Based Education on Human Papilloma Virus Infection and Vaccination

Health Behavior | Human Papilloma Virus

Turkey
Johns Hopkins University
National Institute on Aging (NIA)

Completed

COVID-19 Preventive Behavior in African Americans

Covid19 | Health Behavior

United States
University of Aarhus

Unknown

Fatigue and Quality of Life in Patients With Neuroendocrine Neoplasia

Neuroendocrine Tumors (NET) Health Related Qualito of Life (HRQoL)

Denmark
Assiut University

Completed

Sleep Quality in Healthcare Personnel During COVID-19

COVID-19 | Sleep Quality | General Health

Egypt
Postgraduate Institute of Medical Education and...

Unknown

HCV RAS Testing in Public Health Programs (RAS-HCV)

Hepatitis C | Public Health | Direct Acting Antiviral Agents | Resistance Associated Substitutions

India
Boston Children's Hospital
National Library of Medicine (NLM)

Completed

Parents at the Center: Information Management in ADHD - Clinical Trial

Parents | Attention Deficit Disorder With Hyperactivity | Health Literacy | Information Management | Computer Literacy

United States
Brock University

Not yet recruiting

Mad Dog Cooking Class Series: Effects on Dietary Self-efficacy, Eating Behaviors and Health Outcomes

Depression | Multiple Sclerosis | Inflammation | Spinal Cord Injuries | Diet, Healthy | Adherence, Treatment

Canada
Johns Hopkins University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs

Hyperglycemia | Obesity | Overweight | Weight Loss | PreDiabetes | Prediabetic State | Impaired Glucose Tolerance | Glucose, High Blood | Lifestyle, Healthy | Lifestyle Risk Reduction | Lifestyle, Sedentary

United States
Montreal Heart Institute

Completed

Feasibility of Prediabetes Remission in Adults With Coronary Heart Disease (DIABEPIC1)

Prediabetic State | Coronary Heart Disease | Healthy Lifestyle | Remission

Canada
Janssen Research & Development, LLC

Completed

A Single Ascending Dose Study in Healthy Participants and Multiple Ascending Dose Study of CNTO 7160 in Participants With Asthma and Participants With Atopic Dermatitis

Healthy | Asthma | Atopic Dermatitis

Germany, Belgium
Karolinska Institutet

Unknown

Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD

Attention Deficit Hyperactivity Disorder | Healthy Controls | Emotional Instability Personality Disorder (Borderline Personality Disorder)
University at Buffalo
University of Pavia

Completed

Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS) | Other Neurological Disorders (OND) | Healthy (HC)
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
GlaxoSmithKline

Completed

DDI Study of Etravirine and GSK1265744

Healthy Subjects | Infection, Human Immunodeficiency Virus

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers

Myocardial Ischemia | Coronary Disease | Healthy | Cardiomyopathy, Hypertrophic | Syndrome X

United States
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

Glioma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Central Nervous System Neoplasms | Brain Tumor | High Grade Glioma | Glioma, Malignant | Neoplasm Malignant | Photosensitizing Agents | Tumour, Residual | Brain Neoplasms, Adult, Malignant

Ecuador
Tyra Biosciences, Inc

Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)

Solid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditions

Australia, United States, France, Spain
Allegheny Singer Research Institute (also known...
ElectroCore INC

Terminated

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms (SAVIORII)

Respiratory Failure | COVID | Corona Virus Infection | Respiratory Distress Syndrome, Adult | SARS (Severe Acute Respiratory Syndrome) | ARDS, Human

United States
National Cancer Institute (NCI)

Completed

Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

Recurrent Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Recurrent Adult Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Follicular Lymphoma | Recurrent Lymphoplasmacytic Lymphoma | AIDS-Related Hodgkin Lymphoma

United States
University of California, Davis
National Cancer Institute (NCI); Millennium Pharmaceuticals, Inc.

Completed

Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer

United States
Mayo Clinic

Completed

18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

Ewing Sarcoma of Bone | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor and other conditions

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Completed

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Endometrial Cancer | Desmoid Tumor | Adult Malignant Fibrous Histiocytoma of Bone

United States
European Organisation for Research and Treatment...

Completed

Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Fever, Sweats, and Hot Flashes | Bone Marrow Suppression

Switzerland, United States, Canada, United Kingdom, Belgium, Israel, Slovakia, Finland, Germany, France, Turkey, Czech Republic, Greece
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
Rethink Wellbeing
Maastricht University

Not yet recruiting

Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity. (CT_DoBetter)

Depression | Quality of Life | Cognitive Dysfunction | Anxiety | Loneliness | Treatment Adherence and Compliance | Mental Health Issue | Self Esteem | Interpersonal Relations | Functioning, Psychosocial | Social Functioning | Well-Being, Psychological | Functioning, Social

Netherlands
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

A Study on a Digital Platform for COVID19+ Patients, Designed to Facilitate Communication and Mental-health Care During and After Hospitalization. (DigiCOVID)

COVID-19 | Telemedicine | Mental Health Impairment

Italy
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Active, not recruiting

Burden for STaff Working in the NHS (COST-NHS)

COVID-19 | Mental Health Burden

United Kingdom
Université Catholique de Louvain

Completed

Health Care Use During the Covid19 Crisis (US3R)

Health Care Utilization

Belgium
University Hospital, Bordeaux
France Parkinson Association; Capionis

Completed

Preliminary Study of the Quality of the Oral Flora in Parkinson's Patients (PARKIDENT)

Parkinson Disease | Oral Health

France

Clinical Trials on Adult Healthy Volunteers

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