Clinical Trials on Advanced Solid Malignancy, in Brazil

Total 148 results

Immix Biopharma, Inc.
Novartis; BeiGene

Recruiting

Study of IMX-110 in Combination With Tislelizumab in Patients With Advanced Solid Tumors (IMMINENT-01)

Advanced Solid Tumor

Brazil
Astellas Pharma Global Development, Inc.

Completed

A Rollover Study for Subjects That Have Participated in an Astellas Sponsored Linsitinib Trial

Advanced Solid Tumors

Germany, Czechia, United States, Brazil, Poland, Singapore, Thailand
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Canada, Korea, Republic of, United States, Brazil, Australia, Argentina, Spain, New Zealand, Poland
Janssen Research & Development, LLC

Active, not recruiting

A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations (RAGNAR)

Advanced Solid Tumor

France, United States, Japan, Belgium, United Kingdom, Germany, Korea, Republic of, Taiwan, China, Poland, Italy, Spain, Australia, Brazil, Argentina
Takeda
Takeda Development Center Americas, Inc.

Active, not recruiting

A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

United States, China, Croatia, Japan, Latvia, Poland, Brazil, Lithuania, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

Delirium | Metastatic Malignant Neoplasm | Recurrent Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States, Brazil
Sidnei Epelman

Unknown

Oxaliplatin for Children With Solid Tumors

Relapsed Solid Tumor | Refractory Solid Tumor

Brazil
Amgen

Active, not recruiting

A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

KRAS p.G12C Mutant Advanced Solid Tumors

United States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
Amgen

Completed

AMG 404 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Canada, United States, Belgium, Spain, Brazil, Korea, Republic of, Poland, Singapore, Taiwan, Japan, United Kingdom, Australia, Turkey
Instituto Nacional de Cancer, Brazil

Terminated

Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer (ICAR)

Chemoradiation | Rectal Cancer, Adenocarcinoma | Locally Advanced Malignant Neoplasm

Brazil
Bayer

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body (ON-TRK)

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

United States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
União Química Farmacêutica Nacional S/A
Buranello e Rodrigues Consultoria em Desenvolvimento Farmacêutico Ltda ME

Suspended

Study of Amblyomin-X in Advanced Solid Tumor (Amblyomin-X)

Advanced Cancer

Brazil
Secretaria de Estado da Saúde
Instituto do Cancer do Estado de São Paulo

Terminated

Efficacy and Safety of Synthetic Phosphoethanolamine in Solid Tumor Patients

Solid Tumor

Brazil
Barretos Cancer Hospital

Recruiting

Induction Chemotherapy for Locally Advanced Head and Neck Squamous Cell Carcinoma (INDUCTION)

Locally Advanced Malignant Neoplasm

Brazil
Faculdade de Medicina do ABC

Unknown

Phase II Clinical Trial of Uncaria Tomentosa (Cat´s Claw) in Patients With Advanced Solid Tumors (cat´sclaw)

Solid Tumors

Brazil
NantCell, Inc.
Takeda

Terminated

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas (GAMMA)

Cancer | Pancreatic Cancer | Advanced Solid Tumors | Metastatic Cancer | Bone Metastases | Solid Tumors | Pancreas Cancer | Adenocarcinoma of the Pancreas | Oncology | Cancer of Pancreas | Metastatic Pancreatic Cancer | Metastases | Cancer of the Pancreas | Advanced Malignancy | Oncology Patients | Endocrine Cancer

Italy, Spain, United Kingdom, Belgium, Canada, Denmark, Romania, United States, Germany, Netherlands, Korea, Republic of, Russian Federation, Australia, Austria, Lithuania, Portugal, Greece, Poland, Switzerland, Serbia, Bulgaria, ... and more
University of Sao Paulo

Completed

Talc Pleurodesis in Patients With Recurrent Malignant Pleural Effusion

Recurrent Malignant Pleural Effusion.

Brazil
Hospital Sao Rafael

Completed

Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality (pet-ct)

Hodgkin Disease | Malignant Neoplasm of Breast | Malignant Neoplasm of Colon | Non-Hodgkin Lymphoma, Follicular (Nodular) | Malignant Neoplasm of Bronchus and Lung | Secondary Neoplasm Malignant and Unspecified Lymph Nodes | Malignant Melanoma of the Skin | Malignant Neoplasm of Small Intestine

Brazil
University of Sao Paulo General Hospital

Unknown

Safety and Effectiveness Study for Pleurodesis With Silver Nitrate in Malignant Pleural Effusion

Malignant Pleural Effusion

Brazil
Instituto do Cancer do Estado de São Paulo

Unknown

Non-comparative Study of Treatment With Induction Chemotherapy With Cisplatin and Gemcitabine Followed by Chemoradiation or Definitive Chemoradiation in Invasive Locally Advanced Carcinomas of Uterine Cervix. (CIRCE)

Patients Diagnosed With Advanced Carcinoma of Uterine Cervix t

Brazil
Instituto do Cancer do Estado de São Paulo
Fundação Faculdade de Medicina

Terminated

Feasibility Study of Metronomic Chemotherapy for Locally Advanced HER2-Negative Breast Cancer (TAME-01)

Locally Advanced HER2-negative Breast Cancer

Brazil
Instituto do Cancer do Estado de São Paulo
Fundação Faculdade de Medicina

Terminated

Feasibility Study of Metronomic Chemotherapy for Locally Advanced Her2- Positive Breast Cancer (TraQ-Me 01)

Locally Advanced HER2-positive Breast Cancer

Brazil
Instituto do Cancer do Estado de São Paulo

Completed

Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.

Pancreatic Adenocarcinoma Advanced or Metastatic

Brazil
Instituto Nacional de Cancer, Brazil

Completed

Outpatient Percutaneous Radiologic Gastrostomy in Patients With Head and Neck Tumors

Head and Neck Neoplasms | Gastrostomy | Malignant Neoplasm

Brazil
Instituto do Cancer do Estado de São Paulo

Unknown

Nivolumab in Patients With Advanced Cutaneous Squamous Cell Carcinoma (CA209-9JC)

Advanced Cutaneous Squamous Cell Carcinoma

Brazil
Incyte Corporation

Recruiting

A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Advanced Solid Tumor

Brazil, Georgia, Greece, Turkey, Mexico, Romania, South Africa, Hungary, New Zealand, China
University of Sao Paulo

Completed

Phase I/II Study of Amplitude-Modulated Electromagnetic Fields in the Treatment of Advanced Hepatocellular Carcinoma (TheraBionic)

Advanced Hepatocellular Carcinoma

Brazil
Instituto Brasileiro de Controle do Cancer

Recruiting

Accelerated Partial Breast Irradiation Versus Standard or Hypofractionated Whole-Breast Irradiation, in Early Breast Cancer, After Breast-conserving Surgery (LAPIDARY)

Malignant Neoplasm of Breast

Brazil
Helio Tedesco Silva Junior

Completed

Natural History of Cytomegalovirus (CMV) Infection and Disease Among Renal Transplant Recipients

Infection in Solid Organ Transplant Recipients

Brazil
Instituto Brasileiro de Controle do Cancer

Recruiting

Efficacy and Safety of Ultra_HYPofractionated RadiotHerapy in Women With BrEast CaNcer Receiving Regional Nodal Radiation vs Nodal Moderate Hypofractionated Radiotherapy (HYPHEN)

Malignant Breast Neoplasm

Brazil
University of Sao Paulo

Unknown

Emotional Evaluation and Reconstructed Breast Satisfaction

Malignant Neoplasm of the Breast

Brazil
Instituto Materno Infantil Prof. Fernando Figueira

Unknown

Laser Therapy Prevents Mucositis Oral in Chemotherapy for Bone Marrow Transplantation? (lasertherapy)

Oral Mucositis | Effects of Chemotherapy | Malignant Neoplasm of Bone Marrow

Brazil
Grupo de Pesquisa em Pleura e Oncologia Toracica
Instituto do Cancer do Estado de São Paulo; Instituto do Coracao

Completed

Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion

Pleural Effusion, Malignant

Brazil
Immunocore Ltd

Recruiting

Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

Select Advanced Solid Tumors

United States, Belgium, Korea, Republic of, Australia, Germany, United Kingdom, Spain, Poland, Austria, Brazil, Canada, New Zealand, France, Italy, Netherlands, Switzerland
Novartis Pharmaceuticals

Completed

A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer (PHOENIX I)

Locally Advanced Cervical Cancer

Brazil
Novartis Pharmaceuticals

Completed

A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial Cancer

Endometrial Cancer | VEGF | Solid Tumors and Advanced Endometrial Cancer | Second-line Treatment

Italy, United Kingdom, Spain, Brazil, United States, Korea, Republic of, New Zealand
MARILIA ALBANEZI BERTOLAZZI

Recruiting

Autologous Heterotopic Fresh Ovarian Graft in Woman With LACC Eligible for Pelvic Radiotherapy Treatment.

Locally Advanced Cervical Carcinoma | Premature Ovarian Failure

Brazil
Novartis Pharmaceuticals
Novartis

Withdrawn

Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical Cancer

Treatment for Metastatic or Locally Advanced Cervical Cancer

Brazil
Grupo de Pesquisa em Pleura e Oncologia Toracica
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Relationship Between Pleural Elastance and Effectiveness of Pleurodesis on Recurrent Malignant Pleural Effusion

Pleural Effusion, Malignant

Brazil
Chiltern Pesquisa Clinica Ltda

Completed

Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors

H1N1 Influenza Virus | Invasive Solid Tumors

Brazil
Genentech, Inc.

Recruiting

An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Solid Tumors

Korea, Republic of, Netherlands, Spain, United States, Brazil, Canada, Italy, Australia, Belgium
AstraZeneca

Recruiting

Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

Solid Tumours

Australia, Korea, Republic of, Germany, United States, Spain, France, Canada, Italy, Austria, Israel, United Kingdom, Denmark, Hungary, Poland, Russian Federation, Ukraine, Brazil
Hoffmann-La Roche

Active, not recruiting

A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial

Solid Tumor

Korea, Republic of, China, France, Portugal, Spain, Brazil, Germany, Italy, Peru, Russian Federation, Japan, Ukraine, Costa Rica, Mexico, Poland
Pfizer

Recruiting

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Solid Tumors

United States, Spain, Canada, Italy, Australia, Hungary, Netherlands, United Kingdom, Germany, Brazil, Korea, Republic of, Portugal, France, Japan, Israel, Slovakia, Czechia
Hoffmann-La Roche

Completed

A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)

Malignant Melanoma, Neoplasms

United States, South Africa, Croatia, Brazil, Egypt
Bristol-Myers Squibb

Terminated

Belatacept in Liver Transplant Recipients

Immunosuppression in Solid Organ Transplant

France, Germany, Italy, United States, Austria, Canada, Spain, Argentina, Brazil
Hoffmann-La Roche

Recruiting

Tumor-Agnostic Precision Immuno-Oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Solid Tumors

Belgium, United States, Australia, Canada, Japan, Korea, Republic of, United Kingdom, Germany, Taiwan, China, Puerto Rico, Israel, Singapore, Spain, Brazil, Portugal, South Africa, Denmark, Italy, Poland, Hong Kong, France, New Zealand and more
Hoffmann-La Roche

Recruiting

Screening Study for Participants With Malignant Tumors

Solid Tumors

Korea, Republic of, Belgium, Canada, Australia, Brazil, Taiwan, Japan, Israel, Singapore, Thailand, Italy, Spain, United States, Costa Rica, Hong Kong, Poland, Chile, Serbia, United Kingdom, New Zealand, Turkey, France, Colombia, Norway
Hoffmann-La Roche

Recruiting

A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

Solid Tumours

Brazil, Germany, Taiwan, United Kingdom, France, Turkey, Slovenia, Canada, Ireland, India, Portugal, Thailand, South Africa, Serbia, Israel, Colombia, Spain, Greece, Mexico, Poland, Philippines, Argentina, Egypt, Chile, Estonia, Lebanon, Sl... and more
Hoffmann-La Roche

Completed

A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies

Malignant Melanoma, Neoplasms

Korea, Republic of, Brazil, United States, Canada, Cyprus

Clinical Trials on Advanced Solid Malignancy, in Brazil

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