Clinical Trials on Advanced or Metastatic Liver Cancer

Total 11480 results

Jena University Hospital
University Hospital Tuebingen

Recruiting

Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases (LIVERT(W)OHEAL)

Colorectal Cancer Metastatic | Liver Metastases

Germany
Wuhan YZY Biopharma Co., Ltd.

Active, not recruiting

A Trial of Y101D, a PD-L1/TGF-β Bispecific Antibody, in Patients With Metastatic or Locally Advanced Solid Tumors

Metastatic or Locally Advanced Solid Tumors

China
Jiangsu vcare pharmaceutical technology co., LTD

Completed

Food Effect Study on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Metastatic Malignant Neoplasm in the Lung

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
Novartis Pharmaceuticals

Completed

A Descriptive Study of Baseline Characteristics, Clinical Outcomes, and Treatment Patterns of HR+/HER2- Advanced or Metastatic Breast Cancer Patients Treated With Alpelisib Plus Fulvestrant Who Have Received Fulvestrant in Any Prior Line of Therapy

HR+/HER2- Advanced or Metastatic Breast Cancer

Ireland
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of the Intra-patient Variability of the Quantitative Parameters of Tumor Perfusion Evaluated With Ultrasound Contrast (VARIA-DCE-US)

GIST Metastatic Cancer | Breast Metastatic Cancer | Kidney Metastatic Cancer | Colon Metastatic Cancer | Rectal Metastatic Cancer

France
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of HS-10342 in Chinese Patients With HR+/HER2- Advanced and/or Metastatic Breast Cancer

HR+/HER2- Advanced and/or Metastatic Breast Cancer
Shandong Suncadia Medicine Co., Ltd.

Enrolling by invitation

A Trial of HRS-8080 Tablets in Metastatic or Local Advanced Breast Cancer of Adults

Metastatic or Local Advanced Breast Cancer of Patients

China
Hospital Maciel
University of Adelaide

Completed

Chemotherapy and Tumor Clearance in Hepatic Resections for Colorectal Liver Metastases.

Colorectal Cancer Metastatic | Liver Metastases
Incyte Corporation

Terminated

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

Metastatic Cancer | Solid Tumors | Advanced Malignancies

United States, United Kingdom, Spain
Memorial Sloan Kettering Cancer Center
Novartis Pharmaceuticals

Completed

BYL719 Plus Letrozole or Exemestane for Patients With Hormone-Receptor Positive Locally-Advanced Unresectable or Metastatic Breast Cancer

Metastatic or Locally-advanced Unresectable Breast Cancer

United States
AstraZeneca

Completed

LINE: Treatment Patterns in postmenopausaL Women With Hormone Receptor Positive Breast Cancer (LINE)

Local Advanced or Metastatic Postmenopausal Breast Cancer

Russian Federation
Grupo Espanol Multidisciplinario del Cancer Digestivo

Recruiting

Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease (LIVERPEARL)

Colorectal Cancer Metastatic | Liver Metastasis Colon Cancer

Spain
Mirati Therapeutics Inc.

Approved for marketing

Expanded Access of Adagrasib (MRTX849) in Patients With Advanced Solid Tumors Who Have a KRAS G12C Mutation

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SSGJ-705 Monotherapy in Patients With Advanced Malignant Tumors

Locally Advanced, Recurrent or Metastatic Malignancies

China
Japan Breast Cancer Research Group
Chugai Pharmaceutical

Unknown

A Phase III Trial of Pertuzumab Retreatment in Previously Pertuzumab Treated Her2-Positive Advanced Breast Cancer (PRECIOUS)

HER2-positive Locally Advanced or Metastatic Breast Cancer

Japan
Slawa Cwajna
Nova Scotia Health Authority

Withdrawn

Improving CBCT for Liver IG-SBRT Using Gadoxetate Disodium

Primary Liver Cancer | Metastatic Liver Cancer

Canada
Merck Sharp & Dohme LLC

Recruiting

A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)

Advanced or Metastatic Solid Tumors

Canada, Switzerland, United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of MK-3475A (Pembrolizumab Formulated With MK-5180) In Advanced Solid Tumors (MK-3475A-C18)

Advanced or Metastatic Solid Tumors

Chile, Hungary, Korea, Republic of, South Africa, Spain, Japan
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of SHR-1210 in Combination With Apatinib or Chemotherapy in Subjects With Advanced PLC or BTC

Advanced Biliary Tract Carcinoma | Advanced Primary Liver Cancer

China
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

United States, Korea, Republic of, Spain, Australia, Israel
Mirati Therapeutics Inc.

Recruiting

Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1

Metastatic Cancer | Advanced Cancer | Malignant Neoplastic Disease

United States, Puerto Rico
Abbisko Therapeutics Co, Ltd

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor

Advanced Liver Cancer

China
Guangxi Medical University

Unknown

Combined Immunotherapy and Targeted Therapy for Advanced Liver Cancer

Advanced Liver Cancer

China
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.
Beijing 302 Hospital

Unknown

Study of Activated CIK Armed With Bispecific Antibody for Advanced Liver Cancer

Advanced Liver Cancer

China
Fuda Cancer Hospital, Guangzhou
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.

Withdrawn

Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer

Advanced Liver Cancer

China
M.D. Anderson Cancer Center
National Comprehensive Cancer Network

Completed

Hepatic Arterial Infusion (HAI) of Abraxane

Solid Tumors | Liver Cancer | Advanced Cancers

United States
M.D. Anderson Cancer Center

Completed

HAI Irinotecan + IV Bevacizumab, Bevacizumab & Oxaliplatin or Bevacizumab & Cetuximab in Advanced Cancers Metastatic to Liver

Advanced Cancer | Liver Cancer

United States
Incyte Corporation
Novartis Pharmaceuticals

Completed

A Dose-escalation Study in Subjects With Advanced Malignancies

Solid Tumor | Metastatic Cancer | Advanced Cancer

United States
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy (ASCENT-07)

Stage IV Breast Cancer | Locally Advanced or Unresectable Metastatic Breast Cancer

Taiwan, Korea, Republic of, Australia, Greece, Spain, United States, United Kingdom, France, Israel, Malaysia, Japan, Belgium, Poland, China, Germany, Czechia, Singapore, Hungary, Brazil, Italy, South Africa, Portugal, Argentina, Hong... and more
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer

Metastatic Solid Tumor | Advanced Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study to Evaluate SHR-1210 in Combination With Apatinib as First-Line Therapy in Patients With Advanced HCC

Locally Advanced or Metastatic and Unresectable HCC

United States, Spain, China, Taiwan, Belgium, Korea, Republic of, Italy, Hong Kong, Russian Federation, Ukraine, Turkey, Poland, Germany
M.D. Anderson Cancer Center

Recruiting

Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers

Fatigue | Metastatic Cancers

United States
Pfizer

Recruiting

A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

Advanced or Metastatic Breast Cancer

United States, Taiwan, Canada, Japan, China, Korea, Republic of, Israel, Argentina, Mexico, Australia, Brazil, United Kingdom, India
BeiJing Yijiayi Medicine Techonoloy Co., Ltd.
Dalian Holley Kingkong Pharmaceutical Co., Ltd

Unknown

Clinical Trial of Elemene in Combination With Oxaliplatinin the Treatment of Advanced Primary Liver Cancer

Advanced Primary Liver Cancer

China
City of Hope Medical Center
National Cancer Institute (NCI); Palo Alto Research Center

Completed

Characterization of Circulating Tumor Cells (CTC-s) in Patients With Locally Advanced or Metastatic Stage IV Breast Cancer

Locally Advanced Breast Cancer | Metastatic (Stage IV) Breast Cancer | Stage III-IV Breast Cancer or Inflammatory

United States
Shandong Public Health Clinical Center
Imbioray (Hangzhou) Biomedicine Co., Ltd.

Not yet recruiting

IBR900 Cell Injection Combined With Lenvatinib or Bevacizumab in the Treatment of Advanced Primary Liver Cancer

Advanced Primary Liver Cancer
BeiJing Yijiayi Medicine Techonoloy Co., Ltd.
Dalian Holley Kingkong Pharmaceutical Co., Ltd

Unknown

Clinical Trial of Elemene Injection/Elemene Oral Emulusion in Combination With the Best Supportive Treatment in the Treatment of Advanced Primary Liver Cancer

Advanced Primary Liver Cancer

China
Binhui Biopharmaceutical Co., Ltd.

Recruiting

OH2 Oncolytic Viral Therapy Via Transcatheter Intraarterial Infusion in Patients With Advanced Liver Cancer

Advanced Liver Cancer

China
Jiangsu HengRui Medicine Co., Ltd.
Fudan University; The 81 Hospital of PLA

Completed

Phase III Study of Apatinib Tablets in the Treatment of Advanced or Metastatic Gastric Cancer

Advanced or Metastatic Gastric Cancer

China
Azienda Ospedaliera di Padova

Unknown

Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & Cholangiocarcinoma

Neoplasm Metastasis | Cholangiocarcinoma | Metastatic Liver Cancer

Italy
OSI Pharmaceuticals

Completed

A Study of OSI-7904L Versus 5-FU/LV as Treatment in Patients With Biliary Tract Cancer

Locally Advanced or Metastatic Adenoca of the Biliary Tract

United States, Belgium, Germany, Poland, Romania, Switzerland
Shanghai Zhongshan Hospital

Recruiting

PDO/PDO-TIL/PDOTS for Drug Screen

Liver Cancer | Metastatic Liver Cancer

China
Fudan University

Not yet recruiting

Camrelizumab Combined With Bevacizumab and HAIC in Patients With Metastatic Liver Cancer Who Failed Standard Therapy

Metastatic Liver Cancer

China
Fox Chase Cancer Center
Sirtex Medical

Completed

Study of Capecitabine in Combination With SIR-Spheres in Patients With Advanced Cancer

Metastatic Liver Cancer

United States
Kyowa Kirin Co., Ltd.

Recruiting

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

Advanced or Metastatic Solid Tumors

Japan
AstraZeneca

Active, not recruiting

Safety, Pharmacokinetics and Clinical Activity of AZD0171 in Combination With Durvalumab and Chemotherapy in Locally Advanced or Metastatic Solid Tumours

Locally Advanced or Metastatic Solid Tumours

United States, Spain, Canada, Korea, Republic of
IRCCS San Raffaele

Recruiting

Liver Embolization Approaches for Tumor Management (LEATUM)

Hepatocellular Carcinoma | Metastatic Cancer | Primary Liver Cancer | Cholangiocarcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer | Metastatic Colon Cancer

Italy
Menarini Group

Completed

MEN1611 With Trastuzumab (+/- Fulvestrant) in Metastatic Breast Cancer (B-PRECISE-01)

Advanced or Metastatic Breast Cancer

Spain, Belgium, United Kingdom, France, United States, Italy

Clinical Trials on Advanced or Metastatic Liver Cancer

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