Clinical Trials on Agammaglobulinemia, BTK

Total 90 results

Shanghai Children's Medical Center

Unknown

Mutation of the BTK Gene and Genotype-phenotype Correlation of Chinese Patients With X-Linked Agammaglobulinemia

Agammaglobulinemia, BTK

China
Bio Products Laboratory

Completed

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases (SCIG03)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | X-linked Agammaglobulinaemia | Hyperimmunoglobulin M Syndrome

United States
Bio Products Laboratory

Completed

Bioequivalence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Gammaplex® 10 and Gammaplex® 5% in Primary Immunodeficiency Diseases (GMX07)

Common Variable Immunodeficiency | Primary Immune Deficiency Disorders | Hyper-IgM Syndrome | X-linked Agammaglobulinaemia

United States, United Kingdom, Hungary
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Autosomal Recessive Agammaglobulinemia

Germany, United Kingdom, France, Italy, Poland, Romania, Spain, Sweden, Switzerland
University of South Florida
Merck Sharp & Dohme LLC

Terminated

Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and Older

X-linked Agammaglobulinemia | Specific Antibody Deficiency | Common Variable Immune Deficiency

United States
University Health Network, Toronto
CSL Behring

Completed

Subcutaneous Ig in Allogeneic Stem Cell Transplant Recipients (ScIGalloHCT)

Hypogammaglobulinemia

Canada
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
Prothya Biosolutions

Completed

Kinetics, Efficacy and Safety of IVIG-L in Hypogammaglobulinemia Patients

Hypogammaglobulinemia

Netherlands
Columbia University
Grifols Therapeutics LLC

Completed

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

Lung Transplantation | Hypogammaglobulinemia

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
The Cleveland Clinic

Completed

Cytomegalovirus Hyperimmune Globulin (CMV-Ig) Replacement in Hypogammaglobulinemic Lung Transplant Recipients

Hypogammaglobulinemia

United States
Bio Products Laboratory

Completed

A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency

Common Variable Immunodeficiency | Wiskott-Aldrich Syndrome | X-linked Agammaglobulinemia | Primary Immune Deficiency Disorders | Hyper-IgM Syndrome

United States, Chile, Israel
Monash University

Recruiting

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (RATIONALISE)

Hypogammaglobulinemia | Haematological Malignancy

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome

Infections | Warts | Neutropenia | Myelokathexis | Hypogammaglobulinemia

United States
Baxalta now part of Shire

Completed

Safety, Pharmacokinetic and Efficacy Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Patients With Primary Immunodeficiency (Hypo- or Agammaglobulinemia)

Primary Immunodeficiency Diseases (PID) | Hypogammaglobulinemia | Agammaglobulinemia

Finland, Sweden
Turku University Hospital

Unknown

Clinical and Virological Efficacy of Pegylated Interferon Alpha in the Treatment of Rhinovirus Infection in Patients With Primary Hypogammaglobulinemia: Randomized Controlled Trial (Hypogamma Int1)

Rhinovirus Infection

Finland
Kedrion S.p.A.

Completed

Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency | Hypogammaglobulinemia | Agammaglobulinemia | Antibody Deficiency

United States, Canada
University of Alabama at Birmingham
Grifols Biologicals, LLC

Completed

Post-bypass Prophylactic IVIG in Infants and Neonates

Congenital Heart Disease | Hypogammaglobulinemia

United States
CSL Behring

Completed

Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary Immunodeficiency

Common Variable Immunodeficiency | Agammaglobulinemia

Canada, Germany, Italy, Spain
CSL Behring

Completed

Safety and Efficacy of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency

United States
Centre d'Investigation Clinique et Technologique...

Completed

Upper Limb Botulinum Toxin Injection Combined With Self Rehabilitation (Armautotox)

Self Rehabilitation Combined With BTI on Upper Limb

France
CSL Behring

Completed

Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency
CSL Behring

Completed

Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)

Common Variable Immunodeficiency | Agammaglobulinemia | IgG Deficiency
Federal University of São Paulo
CSL Behring

Completed

Specific IgG Antibody in Patients With Primary Antibody Deficiencies Treated With Subcutaneous Immunoglobulin

Common Variable Immunodeficiency | Agammaglobulinemia

Brazil
Mazandaran University of Medical Sciences

Unknown

Rituximab-Induced Hypogammaglobulinemia in Multiple Sclerosis

Multiple Sclerosis | Hypogammaglobulinemia

Iran, Islamic Republic of
Advanced Neurosciences Institute
Novel Pharmaceutics Institute

Unknown

Immunodeficiency in MS

Multiple Sclerosis | Infection, Bacterial | Immunodeficiency | Hypogammaglobulinemia

United States
Brigham and Women's Hospital

Completed

Personalized Immunotherapeutic for Antibiotic-resistant Infection

Infection | Immune Deficiency | Hypogammaglobulinemia | Septic Arthritis | Mycoplasma Hominis

United States
Insel Gruppe AG, University Hospital Bern

Recruiting

Immunoglobulin Deficiency a Treatable Cause of Fatigue in Patients With Multiple Sclerosis (MS)? (FatIgG)

Multiple Sclerosis | Fatigue | Hypogammaglobulinemia

Switzerland
Octapharma

Recruiting

Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study)

Chronic Lymphocytic Leukemia | Hypogammaglobulinemia

United States, Denmark, Germany, Hungary, Italy, Poland, Russian Federation, Spain, Czechia, Greece, Israel, Turkey
National Institute of Allergy and Infectious Diseases...

Terminated

Cidofovir in Renal Transplant Recipients With BKVN

BK Virus (Nephropathy)

United States
Columbia University
Pfizer; Cornell University

Completed

Using mTOR Inhibitors in the Prevention of BK Nephropathy

BK Viremia | BK Nephropathy

United States
TerSera Therapeutics LLC

Terminated

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer (TELE-ABC)

Biliary Tract Cancer (BTC)

United States
Chinese PLA General Hospital

Unknown

A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC

Biliary Tract Cancer (BTC)

China
Loma Linda University

Withdrawn

BK Virus Post-Kidney Transplant: New Practice Versus Traditional Approach

BK Virus Infection | BK Virus Nephropathy

United States
National Human Genome Research Institute (NHGRI)

Withdrawn

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

ADA-SCID
SL VAXiGEN
SL BIGEN

Unknown

Evaluate Tolerability and Safety of BD03 for Prevention of CMV and BKV Reactivation in Kidney Transplant Recipient

BK Virus Infection | Cytomegalovirus Infections | Preventation of Cytomegalovirus Reactivation | Preventation of BK Virus Reactivation

Korea, Republic of
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Recruiting

The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer

Biliary Tract Cancer (BTC)

Taiwan
TTY Biopharm
National Taiwan University Hospital; Chang Gung Memorial Hospital; Taipei Veterans... and other collaborators

Completed

A Study of S-1 in Combination With Gemcitabine as First-Line Treatment in Patients With Advanced Biliary Tract Cancer

Advanced Biliary Tract Cancer(BTC)

Taiwan
O & O Alpan LLC

Unknown

Investigation of Immune Disorders and Deficiencies

Autoimmune Diseases | Hypogammaglobulinemia | Inflammatory Diseases | Primary Immune Deficiencies | Common Variable Immune Deficiencies

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Fatigue | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Small Lymphocytic Lymphoma | Hypogammaglobulinemia | Lymphocytosis | Night Sweats | Paraproteinemia

United States
AlloVir

Completed

Study of Posoleucel (Formerly Known as ALVR105; Viralym-M) in Kidney Transplant Patients With BK Viremia

BK Virus Infection | BK Virus Nephropathy

United States
Children's Hospital of Philadelphia

Recruiting

Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients (BK-CTLs)

BK Polyomavirus

United States
University Hospital, Strasbourg, France

Active, not recruiting

Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia. (BK EVER)

BK Virus Nephropathy After Kidney Transplantation

France
Dana-Farber Cancer Institute

Active, not recruiting

Prospective Study of BK Virus Disease After Allogeneic Hematopoietic-cell Transplantation: Defining BK Disease's Natural History, Clinical Spectrum, Immunology, and Outcomes

BK Virus Infection

United States
King Chulalongkorn Memorial Hospital

Recruiting

Prediction of BK Virus Reactivation in Kidney Transplant Recipient

BK Virus Infection | Kidney Transplant Infection | BK Virus Nephropathy

Thailand
AlloVir

Withdrawn

Most Closely Human Leukocyte Antigen (HLA)-Matched BK Virus-specific T Lymphocytes (Viralym-B)

BK Virus Infection

United States
Baylor College of Medicine
Patient-Centered Outcomes Research Institute; M.D. Anderson Cancer Center; The... and other collaborators

Completed

Development & Testing of a Decision Aid for LVAD Placement (VADDA)

End-Stage Heart Failure | Bridge-to-Transplant LVAD Placement (BTT) | Destination Therapy LVAD Placement (DT) | Refusal of LVAD Placement (Decliners) | LVAD Caregivers

United States
Astellas Pharma Inc
Astellas Pharma US, Inc.

Terminated

Study of FK778 in Renal Transplant Recipients With Untreated BK Nephropathy

Kidney Diseases | BK Polyomavirus

United States
Memo Therapeutics AG

Completed

Assess Safety, Tolerability and Pharmacokinetics of AntiBKV in Healthy Adult Volunteers. (SAFE KIDNEY I)

BK Virus Nephropathy

Australia
Centre Hospitalier Universitaire de Nice

Completed

Evaluation of a Predictive Immunovirological Test Occurrence of BK Virus Nephropathy in Renal Transplant

Renal Transplant

France

Clinical Trials on Agammaglobulinemia, BTK

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