Clinical Trials on Antibiotic Misuse

Total 57433 results

Michael E. DeBakey VA Medical Center
Baylor College of Medicine

Completed

Fecal Bacterial Flora in Clostridium Difficile-Associated Diarrhea

Enterocolitis | Pseudomembranous Colitis | Antibiotic-Associated Colitis

United States
The Second Hospital of Nanjing Medical University
Wuhan University; The First Affiliated Hospital of Zhengzhou University; First... and other collaborators

Recruiting

Rescue Fecal Microbiota Transplantation for National Refractory Intestinal Infections

Antibiotic-associated Diarrhea | Intestinal Infection | Clostridioides Difficile Infection

China
University of Pennsylvania
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs

Dysbiosis | Clostridium Difficile | Antibiotic-Associated Colitis | Pet-Human Bonding

United States
Erasmus Medical Center
British Society for Antimicrobial Chemotherapy; Saiful Anwar Hospital; University... and other collaborators

Recruiting

The Impact of Covid-19 Hospital Care on the Prevalence of MDRO in Indonesia

COVID-19 | Antibiotic Resistant Infection

Indonesia
United States Naval Medical Center, San Diego

Unknown

Effect of Topical Sinonasal Antibiotics

Chronic Rhinosinusitis (Diagnosis) | Antibiotic Side Effect
Michael E. DeBakey VA Medical Center
Baylor College of Medicine

Completed

Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis

Clostridium Enterocolitis | Pseudomembranous Colitis | Antibiotic-Associated Colitis

United States
Michael E. DeBakey VA Medical Center
Baylor College of Medicine

Completed

Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody

Clostridium Enterocolitis | Pseudomembranous Colitis | Antibiotic-Associated Colitis

United States
Centre Hospitalier Departemental Vendee

Completed

Syndrome and Aspiration Pneumonia in Intensive Care (SPIRE)

ICU Patients | Under Mechanical Ventilation | In State of Coma (Define by Glasgow ≤ 8) | No Antibiotic Treatment

France
Bio-K Plus International Inc.
Sprim Advanced Life Sciences

Completed

Efficacy and Safety Study in the Prevention of Antibiotic-Associated Diarrhea (AAD) and Clostridium Difficile-Associated Diarrhea (CDAD) in Hospitalized Adult Patients Exposed to Nosocomial Infection

Clostridium Difficile-Associated Diarrhea | Antibiotic-Associated Diarrhea
Sultan Qaboos University

Completed

Ventilator Associated Pneumonia by Multi-Drug Resistant Organism (VAP-MDR)

Ventilator Associated Pneumonia | Multi-antibiotic Resistance

Oman
Shanghai 10th People's Hospital

Unknown

Use of Aaerosol Combined With Intravenous Antibiotics for the Treatment of Multidrug Resistant GNB Pneumonia (ACAMP)

Ventilator Associated Pneumonia | Multi-antibiotic Resistance

China
Qianfoshan Hospital

Completed

Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury

Acute Kidney Injury | Beta-Lactam Antibiotic Toxicity (Diagnosis)

China
Batool Mutar

Completed

Antimicrobial Resistance Rate In Escherichia Coli And Klebsiella Pneumonia : A Retrospective Study

Antibiotic Reaction
St Marina University Hospital, Varna, Bulgaria

Completed

Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children (AADreuter)

Gastroenteritis | Clostridium Difficile Infection | Antibiotic Associated Diarrhea

Bulgaria
McMaster University
The Physicians' Services Incorporated Foundation

Completed

Efficacy of Metronidazole Versus Metronidazole and Rifampin in CDAD Treatment

Antibiotic-Associated Diarrhea | Clostridium Enterocolitis | Pseudomembranous Colitis | Pseudomembranous Enterocolitis | Pseudomembranous Enteritis

Canada
Major Extremity Trauma Research Consortium
United States Department of Defense

Recruiting

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation (POvIV2)

Infections | Amputation | Nonunion of Fracture | Antibiotic Side Effect | Fracture | Lower Extremity Fracture | Infected Wound | Injury Leg | Internal Fixation; Complications, Infection or Inflammation

United States
New York Medical College

Unknown

Rifaximin to Modify the Disease Course in Sickle Cell Disease

Sickle Cell Disease | Antibiotics

United States
Buckinghamshire Healthcare NHS Trust
National Institute for Health Research, United Kingdom; Oxford Clinical Trials...

Completed

Preventing UTIs in Chronic Neurogenic Bladder Dysfunction (Mix Methods) (PReSuTINeB)

Neurogenic Bladder | Antibiotic Resistance | UTI

United Kingdom
Sohag University

Recruiting

Phenotypic and Genotypic Variations of Enterococcus Spp

Isolation of Enterococci From Samples | Demonstration of Enterococci Antibiotic Susceptibility | Detection of Strains Enterococci Produce Biofilm | Studying Effect of Nanoparticles on Enterococci Antimicrobial Resistance | Studying Effect of Nanoparticles on Enterococci Biofilm | Genotyping...

Egypt
Nantes University Hospital

Recruiting

Delayed Antibiotic Therapy in Non-severe Ventilator Acquired Pneumonia (VAP) (DELAVAP)

Ventilator Associated Pneumonia | Critical Care | Antibiotic Therapy

France
East Lancashire Hospitals NHS Trust

Not yet recruiting

The MANTRA Trial (MANdibular TRauma and Antibiotic Use) (MANTRA)

Mandible Fracture | Post-operative Antibiotics

United Kingdom
University of Oslo

Completed

Respiratory Tract Infections and Prescription Drugs in Children and in Pregnancy

Respiratory Tract Diagnoses (ICPC-2) | Prescriptions of Antibiotics by General Practitioners | Prescriptions of ATC J01 and R Drugs in Participants

Norway
Technical University of Munich

Recruiting

Helicobacter Pylori Local Prevalence and Antibiotic Resistance (HelicoPTER)

Gastric Cancer | Microbial Colonization | Helicobacter Pylori Infection | Antibiotic Resistant Infection | Helicobacter Pylori Gastritis | Drug Resistant Bacterial Infection

Germany
Genzyme, a Sanofi Company

Completed

A Study of the Absorption of GT267-004 in Patients With Clostridium Difficile-Associated Diarrhea

Antibiotic-Associated Diarrhea | Pseudomembranous Colitis | Clostridium Difficile Diarrhea

Canada
University of Southern Denmark
Hospital of South West Jutland

Not yet recruiting

Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients

Recurrent Urinary Tract Infections | Antibiotic Treatment | Chronic Urinary-catheter-carrier | Biofilm Infection | Replacement of Urinary Catheter
McMaster University

Completed

Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT)

Infections | Diarrhea | Ventilator Associated Pneumonia | Antibiotic-associated Diarrhea | C-Difficile

Canada, United States, Saudi Arabia
Central Hospital, Nancy, France
Reims University Hospital

Unknown

FilmArray and Management of ICU Patients With Pneumonia in the Covid-19 Context (FAP-REA)

Pneumonia | Covid-19 | Infectious Disease | Antibiotic Stewardship | Molecular Diagnosis
University of Monastir

Completed

Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation

Sepsis | Chronic Obstructive Pulmonary Disease | Antibiotics
Vestre Viken Hospital Trust
University of Bergen; Haukeland University Hospital

Recruiting

Comprehensive Molecular Diagnosis and Management of Hospital- and Ventilator-associated Pneumonia in Norway (HVAPNOR)

Infectious Disease | Hospital-acquired Pneumonia | Pneumonia, Ventilator-Associated | Antibiotic Resistant Infection | Infection, Hospital

Norway
University Hospital, Caen

Not yet recruiting

An Antibiotic Protocol Guided by a Multimodal Approach in AECOPD With Pneumonia in Intensive Care (BPCTréa2)

To Reduce Duration of Antibiotics Exposure in Patients With COPD Hospitalized in Intensive Care Unit With Pneumonia

France
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Pediatric Sepsis (CHAMPIONS)

Sepsis | Microbial Colonization | Infection, Bacterial | Antibiotic Side Effect | Sepsis Bacterial | Sepsis, Neonatal

Netherlands
Semmelweis University

Unknown

Ceftolozane-tazobactam for the Treatment of Respiratory Infections Due to Extensively Drug-resistant Pseudomonas Aeruginosa Among Critically Ill Patients: a Retrospective Study.

Ventilator Associated Pneumonia | Antibiotic Resistant Infection

Hungary
Sunnybrook Health Sciences Centre

Enrolling by invitation

Use of Preoperative and Postoperative Antimicrobial Treatment

Surgical Site Infection | Antibiotic Side Effect | Ear Infection Bacterial

Canada
University of California, Los Angeles
LAC+USC Medical Center; Los Angeles County Department of Public Health

Completed

Use of a Behavioral Economic Intervention to Reduce Antibiotic Prescription for Upper Respiratory Infections

Behavioral Economics | Antibiotics | Upper Respiratory Infections | Safety-Net Hospitals | Choosing Wisely

United States
Bolan Medical Complex Hospital Quetta Pakistan

Completed

Predictors of Foot Amputation in Diabetic Foot Ulcers

Diabetic Foot | Amputation | Diabetic Foot Ulcer | Antibiotic Resistant Strain

Pakistan
Cwm Taf University Health Board (NHS)
Cardiff University

Recruiting

The Antibiotic Guardian Study- Clinical Evaluation of a Novel, Rapid Diagnostic for Gonorrhoea and Mycoplasma Infections. (Guardian)

Sexually Transmitted Diseases, Bacterial | Antibiotic Resistant Infection

United Kingdom
National and Kapodistrian University of Athens

Unknown

Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery (MECCA)

Colorectal Cancer | Surgical Site Infection | Bowel Cancer | Antibiotic

Greece
Mikkel Herly
Odense University Hospital; Zealand University Hospital; Aarhus University Hospital and other collaborators

Recruiting

Local Antibiotics for Breast Implants (BREAST-AB)

Antibiotic Side Effect | Implant Complication | Implant Site Infection | Implant Infection | Implant Capsular Contracture | Implant Site Pocket Infection | Implant Expulsion

Denmark
Fariba Nayeri

Unknown

Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.

Meningitis, Bacterial | Infection, Bacterial | Antibiotic Resistant Infection | Nosocomial Infection | Diagnostic Self Evaluation

Sweden
Synspira, Inc.

Terminated

A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis

Lung Diseases | Cystic Fibrosis | Pulmonary Disease | Antibiotic Resistant Infection | Respiratory Tract Disease | Cystic Fibrosis Pulmonary Exacerbation | Lung Inflammation | Burkholderia Infections | Lung Infection | Multi-antibiotic Resistance | Pulmonary Inflammation | Lung Infection Pseudomonal | Cystic Fibrosis... and other conditions

United Kingdom
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
University of Oxford
The Hospital for Sick Children; Oregon Health and Science University; University... and other collaborators

Unknown

Childhood Acute Illness and Nutrition Network (CHAIN)

Pneumonia | Sepsis | Diarrhea | HIV/AIDS | Malnutrition | Bacteremia | Enteropathy | Antibiotic Resistant Strain | TB

Bangladesh, Uganda, Malawi, Pakistan, Kenya
University of California, San Diego

Recruiting

Researchers at UC San Diego Are Learning About the Benefits of Human Milk and How it Influences Infant and Child Health

COVID-19 Vaccine | Breastfeeding | COVID-19 Infection | Antibiotics | Remdesivir

United States
Lund University

Recruiting

Pivmecillinam With Amoxicillin/Clavulanic Acid for Step Down Oral Therapy in ESBL UTIs (PACUTI)

Bacteremia | Urinary Tract Infections | Antibiotic Resistant Infection

Sweden
Association Clinique Thérapeutique Infantile du...
Pfizer

Recruiting

National Bacterial Meningitis Study

Meningitis | Children, Only | Neonatal Infection | Meningococcal Vaccines | Pneumococcal Conjugate Vaccine | Antibiotic Treatment | H. Influenzae Vaccine | Case Fatality Rate

France
Yale University
Brown University; National Institute on Aging (NIA); Advarra

Withdrawn

Electronic Consultation for AD/ADRD Residents Experiencing Infectious Diseases (eCARE-ID)

Dementia | Antibiotics | Nursing Homes | Alzheimer's Dementia
University of Utah
University of Michigan

Enrolling by invitation

Reducing Overuse of Antibiotics at Discharge Home (ROAD Home)

Pneumonia | Urinary Tract Infection | Antibiotic Stewardship | Care Transition

United States
University of Bergen
Haukeland University Hospital; Helse Vest; Muhimbili University of Health and...

Completed

Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant Bacteria (CoTrimResist)

Opportunistic Infections | HIV-1-infection | Antibiotic Side Effect | Pneumocystis Pneumonia | Preventive Therapy

Tanzania
Balgrist University Hospital

Recruiting

Optimal Antibiotics for Operated Diabetic Foot Infections

Surgical Wound | Infection | Antibiotic Side Effect | Diabetic Foot Infection

Switzerland
University of Padova
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Ospedaliera Mater... and other collaborators

Completed

Multi-drug Resistant Gram-negative Bacteria and Veno-venous Extracorporeal Membrane Oxygenation (ECMO) (MDR-ECMO)

Respiratory Distress Syndrome, Adult | Multi-antibiotic Resistance

Italy

Clinical Trials on Antibiotic Misuse

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in New Zealand

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations