Clinical Trials on Antiplatelet De-escalation

Total 304 results

Shenyang Northern Hospital

Not yet recruiting

OCT or Angiography Guided De-escalation of DAPT

ST Elevation Myocardial Infarction | Dual Antiplatelet Therapy | Optical Coherence Tomography | Antiplatelet De-escalation | Neointimal Coverage

China
Bergen University College
Helse-Bergen HF

Completed

Evaluation of Training in De-escalation

De-escalation Skills

Norway
University of Alabama at Birmingham
American Cancer Society, Inc.

Completed

Enhancing Shared Decision-Making in Metastatic Breast Cancer (Qualitative Study)

Decision Making ,Shared | De-escalation

United States
Seoul National University Bundang Hospital

Completed

Does Pantoprazole Reduce the Anti-platelet Effect of Clopidogrel?

Antiplatelet Effect

Korea, Republic of
AstraZeneca

Completed

Study to Investigate Safety and Tolerability of a Single Dose of AZD6482

Antiplatelet Effect
Lee's Pharmaceutical Limited

Suspended

Antiplatelet Thrombolysin (Anfibatide) Phase 1 Clinical Trial in Healthy Volunteers

Antiplatelet Drug

China
Beijing Anzhen Hospital

Unknown

The Influence of Gene Polymorphism on Clinical Outcomes in Patients Undergoing PCI

Antiplatelet Therapy | CYP2C19 Polymorphism

China
Fudan University

Recruiting

Toripalimab Based Induction Chemotherapy Followed by De-escalation Protocols in HPV-related OPSCC

Oropharyngeal Carcinoma | Immune Checkpoint Inhibitor | De-escalation

China
Fudan University

Unknown

De-escalation Protocols in HPV-related Oropharyngeal Carcinoma in Chinese Populations

Oropharyngeal Carcinoma | De-escalation

China
Chiang Mai University

Unknown

Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.

Antiplatelet Agents | Dental Diseases | Antiplatelet Drugs
Brigham and Women's Hospital

Completed

Replication of the PLATO Antiplatelet Trial in Healthcare Claims Data

Antiplatelet

United States
Brigham and Women's Hospital

Completed

Replication of the TRITON-TIMI Antiplatelet Trial in Healthcare Claims Data

Antiplatelet

United States
Rabin Medical Center

Unknown

Is There a Transient Rebound Effect of Platelet Reactivity Following Cessation of Dual Antiplatelet Therapy With Ticagrelor - a Single Center Prospective Observational Trial

Platelet Reactivity | Dual Antiplatelet Therapy

Israel
Jung-min Ahn
CardioVascular Research Foundation, Korea

Active, not recruiting

Perioperative Antiplatelet Therapy in Patients With Drug-eluting Stent Undergoing Noncardiac Surgery (ASSURE-DES)

Antiplatelet Drugs

Korea, Republic of, India, Turkey
Bristol-Myers Squibb
Sanofi

Completed

A Study to Evaluate the Discontinuation Effect of Clopidogrel After Drug Eluting Stent Implantation in Non-diabetic Patients (DECADES)

Antiplatelet Aggregation

France, Germany, Netherlands, United Kingdom
Ruijin Hospital

Completed

DACAB Trial: Follow-up Extension (DACAB-FE)

Coronary Artery Bypass Grafting | Antiplatelet Therapy

China
Chinese Academy of Medical Sciences, Fuwai Hospital

Completed

A Single-center, Prospective,Randomized Study of Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting (ATCCC)

Antiplatelet Therapy of Coronary Artery Bypass

China
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaborators

Recruiting

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy

Nasopharyngeal Carcinoma | De-escalation Therapy

China
Ruijin Hospital

Completed

Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery (DACAB)

Coronary Artery Bypass | Antiplatelet Agents

China
Hotel Dieu de France Hospital

Unknown

Ticagrelor and Endothelial Function

Antiplatelet Agents; Endothelial Function; Pleotropic Effects

Lebanon
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern... and other collaborators

Recruiting

Reduced-target Resection After Induction Chemotherapy in Resectable Recurrent Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | De-escaltion Therapy

China
Riphah International University

Recruiting

Mobilization With Movement Versus Soft Tissue Mobilization in Patients With De Quervain Tenosynovitis

De Quervain Syndrome

Pakistan
AstraZeneca

Completed

Bleeding Time Study With AZD6482, Clopidogrel and ASA

Antiplatelet Effect

Sweden
University Children's Hospital Basel
Swiss National Science Foundation; Fondation Botnar

Completed

Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis (D2OBREATH)

De Novo Lipogenesis (DNL)

Switzerland
Cairo University

Not yet recruiting

Phonophoresis Versus Low-Level Laser on Dequervain

de Quervain Tenosynovitis

Egypt
The University of Hong Kong

Completed

Sinew Acupuncture for de Quervain's Tenosynovitis

de Quervain's Tenosynovitis

Hong Kong
Taipei City Hospital

Completed

Platelet Reactivity (High On-Treatment Platelet Reactivity) as Guidance for APT (Antiplatelet Therapy) Adjustment After PCI (Percutaneous Coronary Intervention)

PRU(Platelet Reactivity Unit) | APT(Antiplatelet Therapy) | HOTPR(High on Treat Platelet Reactivity)

Taiwan
Novartis

Completed

Pharmacokinetic Study of AEB071 in Patients Following Liver Transplantation

de Novo Liver Transplantation

Germany, Italy, Switzerland
University Hospital, Tours
Astellas Pharma Inc

Unknown

Efficacy and Safety Study of a 4-Month Post-Renal Transplant Dose Reduction of Tacrolimus(ADEQUATE) (ADEQUATE)

De Novo Transplant Disease

France
Laboratorios Sophia S.A de C.V.

Completed

Phase IV Study to Evaluate the Efficacy of Lagricel® Ofteno PF Compared to Thealoz® Duo After Photorefractive Keratectomy (PRK) (PRO-037)

Photorefractive Keratectomy | Corneal De-epithelialization

Mexico
Esperion Therapeutics, Inc.

Completed

A Multiple Ascending Dose Study of ETC-1002 in Healthy Subjects

Safety Evaluation of Escalating Doses

United States
Novartis

Completed

Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients

De Novo Kidney Transplant Recipients
Rigshospitalet, Denmark

Completed

Early Detection of de Novo Cancer in Liver Transplant Recipients (DETECT)

Liver Transplant Disorder | De Novo Cancer
Guangdong Provincial People's Hospital
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Zhongshan People's... and other collaborators

Unknown

Long-term MOno-Antiplatelet Drug Strategy After PerCutanEous CoronAry InterveNtion (RESCIND-OCEAN)

Antiplatelet Drug-related Gastrointestinal Injury

China
Icahn School of Medicine at Mount Sinai
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Treatments of Mal de Debarquement Syndrome (MdDS) by Habituation of Velocity Storage

Mal de Debarquement Syndrome (MdDS)

United States
Novartis Pharmaceuticals

Completed

Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients

De Novo Renal Transplantation

Norway
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients

De Novo Kidney Transplantation

Belgium, France, Netherlands, Spain, Sweden, Austria, Italy, Germany, United Kingdom, Hungary, Poland, Czech Republic
Novartis

Completed

Extension Study on the Efficacy and Safety of Enteric-coated Mycophenolate Sodium Administered in de Novo Kidney Transplant Patients

De Novo Kidney Transplantation
University of California, Davis

Recruiting

Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis

De Quervain Tenosynovitis

United States
Azienda Ospedaliero Universitaria Maggiore della...
Abbott Medical Devices

Recruiting

Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study (ARMYDA-AMULET)

Left Atrial Appendage Occlusion | Antiplatelet Therapy

Italy
Astellas Pharma Inc

Completed

Efficacy and Safety of Two Anti-T-lymphocyte Immune Globulin (ATG-F) Induction Regimens in Anew Kidney Transplant Patients

De Novo Kidney Transplant Patients

China
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Effect of Advagraf Conversion From Prograf in Liver Transplant Subjects (Maple)

de Novo Liver Transplant Subjects

Korea, Republic of
Erasmus Medical Center
Hoffmann-La Roche

Completed

Fixed Dose MMF vs Concentration Controlled MMF After Renal Transplantation

De Novo Renal Transplant Recipient.

France, Spain, Taiwan, Denmark, Australia, United Kingdom, Germany, Canada, Belgium, China, Sweden, Netherlands, Austria, Brazil, Estonia, Lithuania, Norway, Poland, Venezuela
Icahn School of Medicine at Mount Sinai
New York University; National Institute on Deafness and Other Communication... and other collaborators

Recruiting

DevRobust Treatment for Mal de Débarquement Syndrome

Mal de Débarquement Syndrome

United States
Medinol Ltd.

Completed

NIRTRAKS Post-Market Study (NIRTRAKS) (NIRTRAKS)

de Novo Stenotic Lesions in Native Coronary Arteries

United States
China Medical University Hospital

Recruiting

Using Ultrasound and Acupuncture to Explore the De-qi Location and Reaction of Specific Acupoints

Ultrasound Imaging | de qi of Acupuncture

Taiwan
NYU Langone Health

Completed

Effectiveness of Astym Treatment For de Quervain's Tenosynovitis

de Quervain's Disease

United States
Icahn School of Medicine at Mount Sinai
Daiichi Sankyo, Inc.; Accumetrics, Inc.

Completed

Patients Undergoing Percutaneous Coronary Intervention (PCI) Through Optimal Platelet Inhibition (TRIAGE)

Aspirin | Percutaneous Coronary Intervention | Dual Antiplatelet Therapy | Clopidogrel

United States
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Ottawa Heart Institute Research Corporation

Terminated

A Novel Strategy For Personalized Long-Term Dual Antiplatelet Therapy (RAPID EXTEND PILOT STUDY)

Percutaneous Coronary Intervention | Ticagrelor | Antiplatelet Therapy | Stable Coronary Syndrome

Canada

Clinical Trials on Antiplatelet De-escalation

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