Clinical Trials on Anus Diseases

Total 377477 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Assessment of Symptom-Related Cytokines in Lung and Gastrointestinal (GI) Cancer Patients

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Lung Cancer | Anal Cancer

United States
Imperial College London

Recruiting

Anal Intraepithelial Neoplasia and Anal Squamous Cell Carcinoma

Anal Cancer | Anal Squamous Intraepithelial Neoplasia

United Kingdom
University of Erlangen-Nürnberg Medical School

Unknown

Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy (HYCAN)

Anal Carcinoma

Germany
Ventrus Biosciences, Inc

Completed

Efficacy and Safety Study With Diltiazem Hydrochloride Cream to Treat Anal Fissures

Chronic Anal Fissures

United States
RDD Pharma Ltd

Completed

An Open Label Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing in Human Subjects

Chronic Anal Fissure

Israel
Hospital General Universitario Elche

Completed

Glyceryl Trinitrate Ointment vs Posterior Tibial Nerve Stimulation in the Treatment of Anal Fissure

Pain
University of Maryland, College Park
National Cancer Institute (NCI)

Completed

A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination

Cervical Cancer | Anal Cancer | Penile Cancer

United States
European Institute of Oncology

Recruiting

Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens

Anal Cancer | High-Risk Cancer | Anal Intraepithelial Neoplasia 2 | Anal Intraepithelial Neoplasia 1

Italy
Sheba Medical Center

Not yet recruiting

Effectiveness of Anal Enlargement by Dilators as a Therapeutic Physical Tool in Acute Anal Fissure

Acute Anal Fissure
Shiraz University of Medical Sciences

Completed

The Efficacy of Asacol (Mesalazine) Suppository on the Treatment of Diarrhea-Induced Acute Fissure

Diarrhea | Fissure in Ano

Iran, Islamic Republic of
RDD Pharma Ltd

Completed

The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients With Anal Fissure

Chronic Anal Fissure

Bulgaria, Moldova, Republic of, Poland, Romania
AIDS Malignancy Consortium
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; University of Arkansas and other collaborators

Completed

Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males

Precancerous Condition | Anal Cancer | Penile Cancer | Nonneoplastic Condition

United States, Puerto Rico
University of Maryland, College Park

Completed

A Chatbot Intervention for Reducing HPV Vaccine Hesitancy

Cervical Cancer | Anal Cancer | Penile Cancer

United States
University Health Network, Toronto
Canadian Foundation for AIDS Research (CANFAR); Ontario HIV Treatment Network

Completed

Screening for HIV-Associated Anal Cancer (TRACE)

HIV Infections | Papillomavirus Infections | Anal Cancer | Anal Dysplasia

Canada
John M. Buatti
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

[F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers

Uterine Cervical Neoplasms | Prostatic Neoplasms | Rectal Neoplasms | Endometrial Neoplasms | Anus Neoplasms

United States
University Health Network, Toronto
Merck Sharp & Dohme LLC

Not yet recruiting

HPV-SAVE_Merck_Sub-Study for Preventing Recurrence of HSIL

Anal Cancer | Human Papilloma Virus | Anal Intraepithelial Neoplasia

Canada
State Scientific Centre of Coloproctology, Russian...
St. Petersburg State Pavlov Medical University; Astrakhan State Medical University and other collaborators

Recruiting

Complex Treatment of a Chronic Anal Fissure

Fissure in Ano

Russian Federation
Sun Yat-sen University

Enrolling by invitation

PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients

Anal Canal Cancer | Anal Squamous Cell Carcinoma | Anal Cancer | Anal Canal Cancer Stage I | Anal Canal Cancer Stage II | Anal Canal Cancer Stage III

China
Bell International Laboratories

Completed

SOOTHER Trial to Treat Rectal Itch

Pruritus Ani

United States
Monash University
The Alfred; University of Melbourne

Recruiting

Human Papillomavirus in Young People Epidemiological Research 4 (HYPER4)

Cancer | Anal Cancer | HPV Infection | HPV | Human Papillomavirus Infection | Men | HPV 16 Infection

Australia
amr bayoumi salama
Cairo University

Enrolling by invitation

Effect of Shock Waves Therapy on Chronic Anal Fissure

Chronic Anal Fissure

Egypt
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus

Precancerous Condition | Anal Cancer

United States
Rikshospitalet University Hospital

Unknown

Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine

Hemorrhoids | Fissure in Ano

Norway
Monash University
The Alfred; University of Melbourne

Recruiting

Human Papillomavirus in Young People Epidemiological Research 3 (HYPER3)

Cancer | Anal Cancer | HPV Infection | HPV | Human Papillomavirus Infection | Men | HPV 16 Infection

Australia
Lasse Krogsbøll

Not yet recruiting

Microbiota in Chronic Anal Fissure and Its Association With Prognosis

Microbial Colonization | Anal Fissure
Manchester University NHS Foundation Trust
University of Liverpool; University of Birmingham; National Institute for Health... and other collaborators

Completed

Packing of Perianal Abscess Cavities (PPAC2)

Perianal Abscess | Perianal Infections | Peri Rectal Abscess | Abscess; Anus | Abscess Anorectal

United Kingdom
University of Palermo

Completed

Oligo-antigenic Diet in the Treatment of Chronic Anal Fissures.

Anal Fissures Treatment and Oligoantigenic Diet

Italy
All India Institute of Medical Sciences, Bhubaneswar

Completed

Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial (PEGASIS)

Constipation | Anal Fissure

India
State Scientific Centre of Coloproctology, Russian...

Recruiting

Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure (BTATCAF)

Chronic Anal Fissure

Russian Federation
AHS Cancer Control Alberta
EMD Serono

Active, not recruiting

Avelumab With Valproic Acid in Virus-associated Cancer (LATENT)

Squamous Cell Carcinoma of the Cervix | Cancer That is Associated With a Chronic Viral Infection | p16 Positive SCCHN | p16 Positive Squamous Cell Carcinoma of the Vagina or Vulva | p16 Positive Squamous Cell Carcinoma of the Penis | p16 Positive Squamous Cell Carcinoma of the Anus or Anal... and other conditions

Canada
National Cancer Institute (NCI)

Active, not recruiting

Extended Follow Up of Young Women in Costa Rica Who Received Vaccine for Human Papillomavirus Types 16 and 18 and Unvaccinated Controls

Cervical Carcinoma | Oral Cavity Carcinoma | Human Papillomavirus Infection | Anal Carcinoma | Human Papillomavirus-Related Cervical Carcinoma

Costa Rica
Tarveda Therapeutics

Recruiting

PEN-866 in Patients With Advanced Solid Malignancies

Neoplasms | Carcinoma | Small Cell Lung Carcinoma | Gastric Cancer | Pancreatic Adenocarcinoma | Solid Tumor | Gastric Adenocarcinoma | Small-cell Lung Cancer | Advanced Cancer | Pancreatic Ductal Adenocarcinoma | Adenocarcinoma of the Pancreas | Endometrial Adenocarcinoma | Squamous Cell Carcinoma of the Penis | Gastroesophageal... and other conditions

United States
University of Roma La Sapienza

Completed

Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments (PBSAAF)

Acute Anal Fissure

Italy
Hadassah Medical Organization

Unknown

Treatment of Anal Fissure by Activated Human Macrophages

Interventional Study | Biological Therapy for Chronic Anal Fissure | Treatment by Biological Factors - Activated Macrophages

Israel
Antiva Biosciences

Terminated

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Anus Neoplasm

United States, Australia
RDD Pharma Ltd

Withdrawn

RDD1609 as a Treatment for Idiopathic Pruritus Ani

Idiopathic Pruritus Ani

United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Vulvar, Vaginal, Penile, Rectal Cancer | HPV Positive Cancer

United States
University Hospital, Basel, Switzerland

Completed

Perianal Nerval Block in Proctological Interventions

Hemorrhoids | Perianal Fistula | Fissure in Ano

Switzerland
Institut de Cancérologie de Lorraine

Completed

Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery (GASVERT)

Head and Neck Cancer | Breast Carcinoma | Cervix Cancer | Melanoma (Skin) | Ovary Cancer | Rectum Cancer | Endometrium Cancer | Vulva Cancer | Squamous Cell Carcinoma, Skin | Anus Cancer

France
Aarhus University Hospital

Recruiting

Circulating Biomarkers in Patients With Anal Cancer Treated With Induction Chemotherapy

Anal Cancer | Circulating Tumor Cell | Oligometastatic Disease | Human Papilloma Virus | Locally Advanced Squamous Cell Carcinoma

Denmark
Solvay Pharmaceuticals

Terminated

Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures

Hemorrhoids | Anal Fissures

Spain
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | HPV Cancers | Vulvar, Vaginal, Penile, Rectal Cancer

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Anal Basaloid Carcinoma | Anal Canal Cloacogenic Carcinoma | Anal Canal Squamous Cell Carcinoma | Anal Margin Squamous Cell Carcinoma | Stage I Anal Cancer AJCC v8 | Stage IIA Anal Cancer AJCC v8

United States
Shattuck Labs, Inc.

Active, not recruiting

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Melanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditions

United States, Canada, Belgium, Spain
Hvidovre University Hospital

Unknown

Ultrasound Guided Lateral Sphincterotomy: Long Term Results

Focus: Anal Incontinence After Lateral Sphincterotomy for Chronic Anal Fissure

Denmark
Karolinska Institutet
Merck Sharp & Dohme LLC

Enrolling by invitation

Education, Immigration and HPV Vaccination: an Informational Randomized Trial

Cervical Cancer | Vulvar Cancer | Head Cancer | Neck Cancer | Genital Wart | Anus Cancer | Penis Cancer | Mouse Papilloma

Sweden
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer

Anal Canal Cloacogenic Carcinoma | Stage III Anal Cancer AJCC v8 | Anal Margin Squamous Cell Carcinoma | Stage IIB Anal Cancer AJCC v8 | Anal Basaloid Squamous Cell Carcinoma

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Anal Cytology Collection Procedures in Predicting High-Grade Anal Dysplasia in Men Who Have Sex With Men

HIV Infection | Human Papillomavirus Infection | Anal Carcinoma

United States
SB Istanbul Education and Research Hospital
Tabriz University of Medical Sciences

Unknown

Effects of Sodium Pentaborat Based Gel on Perianal Benign Diseases

Hemorrhoids | Perianal Fistula | Anal Fissure

Clinical Trials on Anus Diseases

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