Clinical Trials on Aortic Rupture in United States

Total 1383 results

Ad scientiam

Recruiting

Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD (OPTIS)

Neuromyelitis Optica

United States, France
Washington University School of Medicine

Enrolling by invitation

I-Tracking Neurodegeneration in Early Wolfram Syndrome (I-TRACK)

Wolfram Syndrome

United States
Barts & The London NHS Trust
Queen Mary University of London

Completed

Muscle Recovery Following Aortic Surgery Induced ICUAW. (VARIANCE)

Surgery | Critical Illness Myopathy | Aortic Diseases | Intensive Care Unit Syndrome | Intensive Care (ICU) Myopathy | Intensive Care Neuropathy

United Kingdom
Hoffmann-La Roche
Chugai Pharmaceutical Co.

Terminated

A Study In Neuromyelitis Optica Spectrum Disorder (NMOSD) With Satralizumab As An Intervention (SAkuraBonsai)

Neuromyelitis Optica Spectrum Disorder | NMOSD

United States, Korea, Republic of, Italy, Canada, Japan, Turkey
Amylyx Pharmaceuticals Inc.

Active, not recruiting

AMX0035 in Adult Patients With Wolfram Syndrome

Wolfram Syndrome

United States
Mayo Clinic
Terumo BCT

Completed

Maintenance Plasma Exchange for Neuromyelitis Optica (MultiPLEX)

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorder | Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis

United States
Kovach Eye Institute

Recruiting

Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.

Vitrectomy | Retinal Edema | Macular Pucker

United States
University of Washington

Completed

Sugammadex Titration in Cardiac Surgery Patients

Coronary Artery Disease | Heart Failure | Valvular Heart Disease | Aorta Disease

United States
University of Pennsylvania
University of South Florida; Duke University

Recruiting

Vasculitis Pregnancy Registry (V-PREG)

Vasculitis | Wegener's Granulomatosis | Systemic Vasculitis | Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Churg-Strauss Syndrome (CSS) | Cryoglobulinemic Vasculitis | Behcet's Disease | CNS Vasculitis | IgA Vasculitis | Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA) | Polyarteritis... and other conditions

United States
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
University of Pennsylvania

Recruiting

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis (LoDoNaVasc)

Giant Cell Arteritis | Microscopic Polyangiitis | Polyarteritis Nodosa | Granulomatosis With Polyangiitis | Takayasu Arteritis | Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Churg-Strauss Syndrome (CSS)

United States, Canada
University of Pennsylvania

Completed

Journey of Patients With Vasculitis From First Symptom to Diagnosis

Vasculitis | Giant Cell Arteritis | Microscopic Polyangiitis | Polyarteritis Nodosa | Systemic Vasculitis | Granulomatosis With Polyangiitis | Takayasu Arteritis | Cryoglobulinemic Vasculitis | Behcet's Disease | CNS Vasculitis | Temporal Arteritis | IgA Vasculitis | Urticarial Vasculitis | Wegener Granulomatosis | Eosinophilic... and other conditions

United States
Sanofi

Completed

Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis

Multiple Sclerosis | Neuritis | Optic Nerve

United States
University of Texas Southwestern Medical Center

Completed

PEDIATRIC SONICS: Pediatric Study of Neuropsychology and Imaging in CNS Demyelinating Syndromes. (SONICS)

Multiple Sclerosis, Relapsing-Remitting | Neuromyelitis Optica | Transverse Myelitis | Acute Disseminated Encephalomyelitis

United States
Janssen Research & Development, LLC

Terminated

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Rupture | Abdominal Pain | Appendicitis | Peritonitis | Abdominal Abscess | Infection | Ileus | Intestinal Perforation | Abdomen, Acute | Abscess, Intra-Abdominal

United States, Argentina, Colombia, Chile, Panama, Lithuania, Latvia, Brazil
Cedars-Sinai Medical Center

Recruiting

MS-ResearchBiomarkerS (MS-ReBS)

Multiple Sclerosis | Clinically Isolated Syndrome | Multiple Sclerosis, Relapsing-Remitting | Healthy Aging | Neurologic Disorder | Neuromyelitis Optica Spectrum Disorders | Radiologically Isolated Syndrome | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive | Neurologic... and other conditions

United States
St. Jude Children's Research Hospital

Recruiting

Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma

Glioma | Ganglioglioma | Pleomorphic Xanthoastrocytoma | Diffuse Astrocytoma | Pilocytic Astrocytoma | Optic Pathway Glioma | Pilomyxoid Astrocytoma

United States
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

VCRC Tissue Repository

Giant Cell Arteritis | Microscopic Polyangiitis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Eosinophilic Granulomatosis With Polyangiitis | Henoch-Schonlein Purpura | Takayasu Arteritis | Aortitis | IgA Vasculitis | Granulomatosis With Polyangiitis (Wegener's) | Cutaneous Vasculitis

United States, Canada
GenSight Biologics

Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation (RESCUE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, France, Germany, Italy
NYU Langone Health
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

neurofibromatosis1 (NF1) | Recurrent or Progressive Optic Pathway Gliomas (OPG) | Recurrent or Progressive Low-grade Glioma

United States
Oxford Brookes University
Guy's and St Thomas' NHS Foundation Trust; Oxford University Hospitals NHS... and other collaborators

Recruiting

Lifestyle Weight Management Program: Interviews and Stakeholder Meetings.

Multiple Sclerosis | Neuromyelitis Optica

United Kingdom
GenSight Biologics

Completed

Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE) (REVERSE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, Germany, Italy, France
Centre hospitalier de l'Université de Montréal...
Centre Hospitalier Régional et Universitaire de Brest

Recruiting

Treatment of Brain AVMs (TOBAS) Study (TOBAS)

Arteriovenous Malformations | Unruptured Brain Arteriovenous Malformation | Ruptured Brain Arteriovenous Malformation | AVM | BAVM

France, United States, Canada, Brazil, Chile, Colombia
University of Oxford
Multiple Sclerosis Society of Great Britain and Northern Ireland

Completed

Amiloride Clinical Trial In Optic Neuritis (ACTION)

Multiple Sclerosis | Optic Neuritis

United Kingdom
Children's National Research Institute

Completed

Accuracy of the Red Reflex Test in the Pediatric Population

Optic Nerve Diseases | Retinal Disease | Retinal Hemorrhage | Abnormal Vitreous Humor Morphology | Abnormal Choroid Morphology

United States
Northwell Health

Enrolling by invitation

Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System (OGS)

Pressure Injury | Barotrauma | Otic Barotrauma | Ear Injury | Barotitis

United States
Cook Group Incorporated

Completed

PRESERVE-Zenith® Iliac Branch System Clinical Study

Aorto-iliac Aneurysms | Iliac Aneurysms

United States
University of British Columbia
University of Oxford; BC Childrens Hospital Research Institute

Recruiting

Pediatric Vasculitis Initiative (PedVas)

Microscopic Polyangiitis | Polyarteritis Nodosa | Eosinophilic Granulomatosis With Polyangiitis | Takayasu Arteritis | Wegeners Granulomatosis (Granulomatosis With Polyangiitis) | Primary CNS Vasculitis | Unclassified Vasculitis

Canada, United States, Thailand, United Kingdom, Germany, India, Denmark
Birmingham Women's and Children's NHS Foundation...

Recruiting

Recurrent Nerve Monitoring During Aortic Arch Repair (PREMAR)

Recurrent Laryngeal Nerve Injuries | Aortic Arch Hypoplasia

United Kingdom
University College, London
National Multiple Sclerosis Society; Multiple Sclerosis Society of Great Britain...

Completed

Neuroprotection With Phenytoin in Optic Neuritis

Multiple Sclerosis | Optic Neuritis

United Kingdom
Cook Group Incorporated

No longer available

PRESERVE-Zenith® Iliac Branch System Clinical Extended Study

Aorto-iliac Aneurysms | Iliac Aneurysms

United States
National Eye Institute (NEI)

Unknown

Longitudinal Optic Neuritis Study (LONS)

Multiple Sclerosis | Optic Neuritis

United States
National Eye Institute (NEI)

Unknown

Optic Neuritis Treatment Trial (ONTT)

Multiple Sclerosis | Optic Neuritis

United States
Cook Group Incorporated

Terminated

Zenith(R) Connection Endovascular Covered Stent Clinical Study

Aorto-iliac Aneurysms | Iliac Aneurysms

Hong Kong, United Kingdom, Germany
Southeast Clinical Research Associates, LLC
Genentech, Inc.

Completed

Efficacy of Biweekly Ranibizumab (0.5 mg) for Exudative Macular Degeneration Retinal Edema Refractory to Anti-VEGF

Exudative Age Related Macular Degeneration

United States
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

Efficacy and Safety Study of Satralizumab (SA237) as Add-on Therapy to Treat Participants With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD)

Neuromyelitis Optica (NMO) | NMO Spectrum Disorder (NMOSD)

Spain, Italy, United States, Japan, Poland, Taiwan, Germany, United Kingdom, Hungary, France, Ukraine
Exactech

Recruiting

Exactech Shoulder Post Market Clinical Follow-up Study

Infections | Rheumatoid Arthritis | Post-traumatic Osteoarthritis | Osteonecrosis | Rotator Cuff Tears | Ankylosing Spondylitis | Fracture | Osteo Arthritis Shoulders | Rotator Cuff Tear Arthropathy

United States, United Kingdom, France, Italy
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Recruiting

One-Time DNA Study for Vasculitis

Giant Cell Arteritis | Microscopic Polyangiitis | Polyarteritis Nodosa | Takayasu's Arteritis | Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) | Granulomatosis With Polyangiitis (Wegener's)

United States, Canada, Turkey
Cambridge University Hospitals NHS Foundation Trust

Active, not recruiting

Biologics in Refractory Vasculitis (BIOVAS)

Giant Cell Arteritis | Polyarteritis Nodosa | Takayasu Arteritis | Cryoglobulinemic Vasculitis | IgA Vasculitis | Cogan Syndrome | Relapsing Polychondritis | Cutaneous Polyarteritis Nodosa | Primary Angiitis of Central Nervous System

United Kingdom
Alexion Pharmaceuticals, Inc.

Recruiting

Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD

Neuromyelitis Optica Spectrum Disorder

United States, Italy, Korea, Republic of, Japan, France, Germany, Spain, Canada
Valley Retina Institute

Completed

Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study (PRESERVE)

Diabetic Macular Edema

United States
University of Colorado, Denver
National Institute on Aging (NIA)

Completed

Advancing Understanding of Transportation Options (AUTO)

Stroke | Multiple Sclerosis | Glaucoma | Brain Injuries | Macular Degeneration | Arthritis | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Restless Legs Syndrome | Diabetic Retinopathy | Insomnia | Retinitis Pigmentosa | Obstructive Sleep Apnea | Dementia | End Stage Renal Disease | Sleep Apnea | Syncope | Seizures and other conditions

United States
Alexion Pharmaceuticals, Inc.

Terminated

A Study of the Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorder

United States, Italy, Canada, Japan, Spain, Korea, Republic of, Germany
Hoffmann-La Roche

Completed

A Study to Evaluate the Safety and Efficacy of Satralizumab in Participants With Neuromyelitis Optica Spectrum Disorder (NMOSD)

Neuromyelitis Optica Spectrum Disorder

United States, Spain, United Kingdom, Taiwan, Hungary, Korea, Republic of, Japan, Croatia, Bulgaria, Canada, Germany, Italy, Poland, Puerto Rico, Romania, Turkey, Ukraine, Malaysia
Northwell Health

Not yet recruiting

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

Obstructive Sleep Apnea | Normal Tension Glaucoma

United States
Great Ormond Street Hospital for Children NHS Foundation...
AstraZeneca

Completed

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT)

Neurofibromatosis Type 1 | Optic Nerve Glioma | Plexiform Neurofibroma

United Kingdom
Targeted Therapy Technologies, LLC

Recruiting

Phase I Study of Episcleral Celecoxib for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole

Macula Edema | Epiretinal Membrane | Branch Retinal Vein Occlusion | Radiation Retinopathy | Central Serous Retinopathy With Pit of Optic Disc | Commotio Retinae | Vitritis

United States
Alexion

Active, not recruiting

An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD

Neuromyelitis Optica | Neuromyelitis Optica Spectrum Disorder

United States, Australia, Austria, Canada, Denmark, France, Germany, Italy, Japan, Korea, Republic of, Poland, Spain, United Kingdom
National Institute of Arthritis and Musculoskeletal...

Terminated

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

Nervous System Malformations | Urticaria | Papilledema | Arthropathy, Neurogenic

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Avutometinib for People With Solid Tumor Cancers

Solid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene Mutation

United States

Clinical Trials on Aortic Rupture in United States

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